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An in vitro model of adipose tissue-associated macrophages
An in vitro model of adipose tissue-associated macrophages
Obesity-related chronic low-grade inflammation plays a central role in the development of insulin resistance. Macrophages ...
A majority of circadian clock genes are expressed in estrogen receptor and progesterone receptor status-dependent manner in breast cancer
A majority of circadian clock genes are expressed in estrogen receptor and progesterone receptor status-dependent manner in breast cancer
Circadian clocks, biochemical oscillators that are regulated by environmental time cues including the day/night cycle, hav...
CDCA: Community detection in RNA-seq data using centrality-based approach
CDCA: Community detection in RNA-seq data using centrality-based approach
One of the integral part of the network analysis is finding groups of nodes that exhibit similar properties. Community det...
Wisdom of (molecular) crowds: How a snake’s temperature-sensing superpower separates information from misinformation
Wisdom of (molecular) crowds: How a snake’s temperature-sensing superpower separates information from misinformation
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishin...
IRF9 and STAT1 as biomarkers involved in T-cell immunity in atherosclerosis
IRF9 and STAT1 as biomarkers involved in T-cell immunity in atherosclerosis
Atherosclerosis is a common cardiovascular disease in which the arteries are thickened due to buildup of plaque. This stud...
MicroRNA dynamics in irisin-mediated signaling pathways within adipose tissue
MicroRNA dynamics in irisin-mediated signaling pathways within adipose tissue
The regulation of adipose tissue metabolism by irisin involves modulating gene expressions related to energy metabolism an...
Role of gustatory neurons opposing TGF-β in regulating nictation behavior in Caenorhabditis elegans
Role of gustatory neurons opposing TGF-β in regulating nictation behavior in Caenorhabditis elegans
The transforming growth factor beta (TGF-β) signaling pathway is implicated in various physiological processes, inclu...
Estimating protein–ligand interactions with geometric deep learning and mixture density models
Estimating protein–ligand interactions with geometric deep learning and mixture density models
Understanding the interactions between a ligand and its molecular target is crucial in guiding the optimization of molecul...
Enhancing access to treatment for Gaucher disease in India: The need for indigenous manufacturing
Enhancing access to treatment for Gaucher disease in India: The need for indigenous manufacturing
Gaucher disease (GD) is a prevalent lysosomal storage disorder (LSD) that significantly impacts individuals’ lives. ...
Finding identical sequence repeats in multiple protein sequences: An algorithm
Finding identical sequence repeats in multiple protein sequences: An algorithm
In recent years, several experimental evidences suggest that amino acid repeats are closely linked to many disease conditi...
Dynein functions in galectin-3 mediated processes of clathrin-independent endocytosis
Dynein functions in galectin-3 mediated processes of clathrin-independent endocytosis
Multiple endocytic processes operate in cells in tandem to uptake multiple cargoes involved in diverse cellular functions,...
Cobra (Naja naja) venom L-amino acid oxidase (NNLAAO70) induces apoptosis and secondary necrosis in human lung epithelial cancer cells
Cobra (Naja naja) venom L-amino acid oxidase (NNLAAO70) induces apoptosis and secondary necrosis in human lung epithelial cancer cells
Snake venom L-amino acid oxidases (LAAOs) are flavoenzymes with diverse physiological and pharmacological effects. These e...
Crosstalk between photosynthesis and respiration in microbes
Crosstalk between photosynthesis and respiration in microbes
Phototrophic organisms harbor two main bioenergetic hubs, photosynthesis and respiration, and these processes dynamically ...
From sequence to consequence: Deciphering the complex cis-regulatory landscape
From sequence to consequence: Deciphering the complex cis-regulatory landscape
Cell type-specific expression of genes plays a pivotal role in the development and evolution of multicellular organisms ov...
Tumor cell type and gene marker identification by single layer perceptron neural network on single-cell RNA sequence data
Tumor cell type and gene marker identification by single layer perceptron neural network on single-cell RNA sequence data
Tumors have drawn increasing attention recently because of their heterogeneous interior structures. Particularly, single-c...
Visual plant anatomy: From science to education and vice versa
Visual plant anatomy: From science to education and vice versa
Plant biology, mainly plant anatomy, is a less attractive area for students at high school and university, but not much re...
Predicting and reducing potential parasite infection between migratory livestock and resident Asiatic ibex of Pin valley, India
Predicting and reducing potential parasite infection between migratory livestock and resident Asiatic ibex of Pin valley, India
Disease cross-transmission between wild and domestic ungulates can negatively impact livelihoods and wildlife conservation...
Discovery of antibacterial biogenic magnetosome nanoparticles from Providencia sp. MTBPRB-1: Screening, purification and characterization
Discovery of antibacterial biogenic magnetosome nanoparticles from Providencia sp. MTBPRB-1: Screening, purification and characterization
Bacterial species referred to as magnetotactic bacteria (MTB) biomineralize iron oxides and iron sulphides inside the cell...
Mitochondrial alternative oxidase pathway helps in nitro-oxidative stress tolerance in germinating chickpea
Mitochondrial alternative oxidase pathway helps in nitro-oxidative stress tolerance in germinating chickpea
Mitochondrial alternative oxidase (AOX) is an important protein that can help in regulating reactive oxygen species and ni...
SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the PI3K/Akt signaling pathway
SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the PI3K/Akt signaling pathway
Lung cancer (LC) is the leading cause of cancer-associated deaths worldwide, among which non-small-cell lung cancer (NSCLC...
Systems biology of plant metabolic interactions
Systems biology of plant metabolic interactions
Metabolism is the key cellular process of plant physiology. Understanding metabolism and its dynamical behavior under diff...