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Should a borderline negative HER2 result in a core biopsy of invasive carcinoma of the breast have HER2 assessment repeated in the excision specimen?
Should a borderline negative HER2 result in a core biopsy of invasive carcinoma of the breast have HER2 assessment repeated in the excision specimen?
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PD-L1 protein expression in breast cancer
PD-L1 protein expression in breast cancer
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Cross-sectional study to evaluate the utility of elastic tissue staining in primary cicatricial alopecia
Cross-sectional study to evaluate the utility of elastic tissue staining in primary cicatricial alopecia
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Correlation of low numbers of intratumoral FOXP3+ cells with worse progression-free survival in angioimmunoblastic T cell lymphoma
Correlation of low numbers of intratumoral FOXP3+ cells with worse progression-free survival in angioimmunoblastic T cell lymphoma
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Molecular diagnosis of tuberous sclerosis complex in fetuses and infants: an institutional case series
Molecular diagnosis of tuberous sclerosis complex in fetuses and infants: an institutional case series
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Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma
Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma
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Phaeochromocytoma and paraganglioma
Phaeochromocytoma and paraganglioma
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Comparing the diagnostic efficacy of optical coherence tomography and frozen section for margin assessment in breast-conserving surgery: a meta-analysis
Comparing the diagnostic efficacy of optical coherence tomography and frozen section for margin assessment in breast-conserving surgery: a meta-analysis
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Does an electronic pathology ordering system change the volume and pattern of routine testing in hospital? An interrupted time series analysis
Does an electronic pathology ordering system change the volume and pattern of routine testing in hospital? An interrupted time series analysis
IntroductionWith increasing healthcare costs and an ageing population, identifying and resolving causes of low-value care ...
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
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Intraoperative evaluation of sentinel lymph nodes in patients with breast cancer treated with systemic neoadjuvant therapy
Intraoperative evaluation of sentinel lymph nodes in patients with breast cancer treated with systemic neoadjuvant therapy
WHAT IS ALREADY KNOWN ON THIS TOPICTouch preparation (TP) is an easy and rapid method to detect metastasis during intraope...
The Impact of potential 'confounders on the diagnostic sensitivity of circulating free DNA in management of FIT+ patients: a pilot study
The Impact of potential 'confounders on the diagnostic sensitivity of circulating free DNA in management of FIT+ patients: a pilot study
IntroductionMetastatic colorectal cancer (mCRC) is still one of the leading causes of death worldwide.1 Despite improvemen...
Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a clinicopathological study of three cases
Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a clinicopathological study of three cases
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Sample suitability and stability in different blood collection tubes for methanol, ethanol, isopropanol, acetone and glycols analysis
Sample suitability and stability in different blood collection tubes for methanol, ethanol, isopropanol, acetone and glycols analysis
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Performances of the Idylla GeneFusion Assay: contribution to a rapid diagnosis of targetable gene fusions in tumour samples
Performances of the Idylla GeneFusion Assay: contribution to a rapid diagnosis of targetable gene fusions in tumour samples
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Stability of porphyrins and porphyrin precursors in urine and plasma samples: implications for sample handling and storage
Stability of porphyrins and porphyrin precursors in urine and plasma samples: implications for sample handling and storage
The porphyrias are rare disorders of haem biosynthesis. Diagnosis requires demonstrating increased porphyrins or porphyrin...
Gene of the month: DDIT3
Gene of the month: DDIT3
DNA damage-inducible transcript 3 (DDIT3) gene, mapped to the human chromosome 12q13.3, encodes a protein that belongs to ...
Gender distribution in pathology journal editorial boards: a call to action
Gender distribution in pathology journal editorial boards: a call to action
The article by Nguyen et al reveals that Pathology, like other medical specialties, has an underrepresentation of women au...
Gender distribution in surgical pathology journal publications and editorial boards
Gender distribution in surgical pathology journal publications and editorial boards
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Risk assessment in pT1 colorectal cancer
Risk assessment in pT1 colorectal cancer
IntroductionColorectal cancer (CRC) is one of the most common malignancies, resulting in 16 800 deaths in the UK annually....
Expression and correlation of PD-L1 and HER2 in oesophageal squamous cell carcinoma
Expression and correlation of PD-L1 and HER2 in oesophageal squamous cell carcinoma
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Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma
Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma
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Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens
Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionTriple-negative bre...
Tumour-to-tumour metastasis of breast cancer (donor) and clear cell renal cell carcinoma (recipient): a case report
Tumour-to-tumour metastasis of breast cancer (donor) and clear cell renal cell carcinoma (recipient): a case report
A woman in her late 70s was referred to urology clinic to consider intervention for a biopsy-proven 24 mm WHO/Internationa...
Kinase expression in angiomatoid fibrous histiocytoma: panTRK is commonly expressed in the absence of NTRK rearrangement
Kinase expression in angiomatoid fibrous histiocytoma: panTRK is commonly expressed in the absence of NTRK rearrangement
Angiomatoid fibrous histiocytoma (AFH) is a soft tissue tumour of intermediate (rarely metastasising) malignant potential,...
Efficacy of postmortem CT and tissue sampling in establishing the cause of death in clinical practice: a prospective observational study
Efficacy of postmortem CT and tissue sampling in establishing the cause of death in clinical practice: a prospective observational study
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Non-deletional haemoglobin H (Hb H) disease morphologically masquerading as congenital dyserythropoietic anaemia type II: a diagnostic pitfall
Non-deletional haemoglobin H (Hb H) disease morphologically masquerading as congenital dyserythropoietic anaemia type II: a diagnostic pitfall
Haemoglobin H (Hb H) disease is a form of alpha (α)-thalassaemia where three of the four α-globin gene alleles are deleted...
Implementation of an ISO15189 accredited next-generation sequencing service with the fully automated Ion Torrent Genexus: the experience of a clinical diagnostic laboratory
Implementation of an ISO15189 accredited next-generation sequencing service with the fully automated Ion Torrent Genexus: the experience of a clinical diagnostic laboratory
WHAT IS ALREADY KNOWN ON THIS TOPICThis is a new concept, the implementation of an ISO15189 accredited next-generation seq...
Successful demand management in diagnostic immunology testing
Successful demand management in diagnostic immunology testing
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Modes of assay interference and the effectiveness of serum pretreatment approaches in detection of anti-HLA antibodies
Modes of assay interference and the effectiveness of serum pretreatment approaches in detection of anti-HLA antibodies
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