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Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study
The phase III KEYNOTE-913 study was conducted to evaluate the efficacy and safety of pembrolizumab as first-line therapy i...
The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted gr...
Predictors and Management of Inadequate Response to JAK Inhibitors in Alopecia Areata
Predictors and Management of Inadequate Response to JAK Inhibitors in Alopecia Areata
Alopecia areata is a common autoimmune disorder characterized by non-scarring hair loss on the scalp or other hair-bearing...
Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments
Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments
Erythroderma, an inflammatory skin condition characterized by widespread erythema with variable degrees of exfoliation, pu...
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most severe cutaneous adverse reactions ...
A Practice Approach to Acne Fulminans in Adolescents
A Practice Approach to Acne Fulminans in Adolescents
Acne fulminans (AF) is a severe form of inflammatory acne commonly associated with adolescents. It is characterized by an ...
Image-Based Artificial Intelligence in Psoriasis Assessment: The Beginning of a New Diagnostic Era?
Image-Based Artificial Intelligence in Psoriasis Assessment: The Beginning of a New Diagnostic Era?
Psoriasis, a chronic inflammatory skin disease, affects millions of people worldwide. It imposes a significant burden on p...
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice
Intralesional corticosteroid administration (ICA) is a first-line keloid treatment. However, it faces significant variabil...
Chronic Hand Eczema
Chronic Hand Eczema
Chronic hand eczema (CHE) is a complex, challenging, and frequently multifactorial skin disease of the hands. It is very c...
Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review
Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review
Many morphological and histological changes take place in aging skin. Topical tretinoin is the gold standard anti-aging ag...
Managing Urticarial Vasculitis: A Clinical Decision-Making Algorithm Based on Expert Consensus
Managing Urticarial Vasculitis: A Clinical Decision-Making Algorithm Based on Expert Consensus
Urticarial vasculitis (UV) is a rare and difficult-to-treat, small-vessel leukocytoclastic vasculitis presenting with recu...
Intravenous Immunoglobulin Therapy for Pyoderma Gangrenosum: A Multicenter Retrospective Analysis in 81 Patients
Intravenous Immunoglobulin Therapy for Pyoderma Gangrenosum: A Multicenter Retrospective Analysis in 81 Patients
Pyoderma gangrenosum (PG) is rare neutrophil skin disease causing painful, progressively enlarging ulcers. Among the treat...
Ruxolitinib Cream Monotherapy Improved Symptoms and Quality of Life in Adults and Adolescents with Mild-to-Moderate Atopic Dermatitis: Patient-Reported Outcomes from Two Phase III Studies
Ruxolitinib Cream Monotherapy Improved Symptoms and Quality of Life in Adults and Adolescents with Mild-to-Moderate Atopic Dermatitis: Patient-Reported Outcomes from Two Phase III Studies
Atopic dermatitis (AD) is associated with itch, skin pain, sleep disturbances, and diminished quality of life (QoL). Ruxol...
Multiple Keratoacanthomas Associated with Genetic Syndromes: Narrative Review and Proposal of a Diagnostic Algorithm
Multiple Keratoacanthomas Associated with Genetic Syndromes: Narrative Review and Proposal of a Diagnostic Algorithm
Keratoacanthoma (KA) is a relatively common, fast-growing epithelial tumour, with characteristic behaviour and clinical va...
Ultrasound Surveillance in Melanoma Management: Bridging Diagnostic Promise with Real-World Adherence: A Systematic Review and Meta-Analysis
Ultrasound Surveillance in Melanoma Management: Bridging Diagnostic Promise with Real-World Adherence: A Systematic Review and Meta-Analysis
Ultrasound surveillance has become the new standard of care in stage III melanoma after the 2017 Multicenter Selective Lym...
Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates
Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates
Merkel cell carcinoma (MCC) is a rare skin cancer characterized by neuroendocrine differentiation. Its carcinogenesis is b...
Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
Early and Sustained Improvements in Symptoms and Quality of Life with Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: 52-Week Results from Two Phase III Randomized Clinical Trials (Measure Up 1 and Measure Up 2)
Atopic dermatitis is a chronic inflammatory disease characterized by increased itch, skin pain, poor sleep quality, and ot...
Expert Panel Review of Skin and Hair Dermatophytoses in an Era of Antifungal Resistance
Expert Panel Review of Skin and Hair Dermatophytoses in an Era of Antifungal Resistance
Dermatophytoses are fungal infections of the skin, hair, and nails that affect approximately 25% of the global population....
The Impact of Dermatologic Adverse Events on the Quality of Life of Oncology Patients: A Review of the Literature
The Impact of Dermatologic Adverse Events on the Quality of Life of Oncology Patients: A Review of the Literature
Dermatologic adverse events resulting from oncologic therapy are common and negatively impact patients’ quality of l...
Rapidly Evolving Pre- and Post-surgical Systemic Treatment of Melanoma
Rapidly Evolving Pre- and Post-surgical Systemic Treatment of Melanoma
With the development of effective BRAF-targeted and immune-checkpoint immunotherapies for metastatic melanoma, clinical tr...
Tree-Based Machine Learning to Identify Predictors of Psoriasis Incidence at the Neighborhood Level: A Populational Study from Quebec, Canada
Tree-Based Machine Learning to Identify Predictors of Psoriasis Incidence at the Neighborhood Level: A Populational Study from Quebec, Canada
Psoriasis is a major global health burden affecting ~ 60 million people worldwide. Existing studies on psoriasis focused o...
OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target
OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target
Atopic dermatitis (AD) is a chronic, heterogeneous, inflammatory disease characterized by skin lesions, pruritus, and pain...
Small-Molecule Inhibitors and Biologics for Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis
Small-Molecule Inhibitors and Biologics for Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis
The comparative efficacy of biologics and small-molecule inhibitors in treating palmoplantar psoriasis (PP) and palmoplant...
Therapeutic Strategies in BRAF V600 Wild-Type Cutaneous Melanoma
Therapeutic Strategies in BRAF V600 Wild-Type Cutaneous Melanoma
There have been many recent advances in melanoma therapy. While 50% of melanomas have a BRAF mutation and are a target for...
Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies
Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies
Atopic dermatitis (AD), a highly pruritic, inflammatory skin disease, affects approximately 7% of adolescents globally. A ...
Approach to the Atypical Wound
Approach to the Atypical Wound
The heterogeneity of atypical wounds can present diagnostic and therapeutic challenges; however, as the prevalence of atyp...
Dupilumab Safety and Efficacy up to 1 Year in Children Aged 6 Months to 5 Years with Atopic Dermatitis: Results from a Phase 3 Open-Label Extension Study
Dupilumab Safety and Efficacy up to 1 Year in Children Aged 6 Months to 5 Years with Atopic Dermatitis: Results from a Phase 3 Open-Label Extension Study
Pediatric patients with moderate-to-severe atopic dermatitis (AD) often experience a high disease burden and have a high r...
Managing the Patient with Psoriasis and Metabolic Comorbidities
Managing the Patient with Psoriasis and Metabolic Comorbidities
Epidemiological data demonstrate strong associations between psoriasis and metabolic comorbidities, including obesity, hyp...
Treat-to-Target in Atopic Dermatitis
Treat-to-Target in Atopic Dermatitis
Atopic dermatitis is one of the most common inflammatory skin diseases among children and adults. Over the last 5 years, t...
Author Correction: Efficacy and Safety of Apremilast for the Treatment of Japanese Patients with Palmoplantar Pustulosis: Results from a Phase 2, Randomized, Placebo-Controlled Study
Author Correction: Efficacy and Safety of Apremilast for the Treatment of Japanese Patients with Palmoplantar Pustulosis: Results from a Phase 2, Randomized, Placebo-Controlled Study
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International ...
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