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Continuous Electroencephalography in Acute Liver Failure: Findings and Prognostic Value
Continuous Electroencephalography in Acute Liver Failure: Findings and Prognostic Value
Neurologic complications contribute significantly to morbidity and mortality in acute liver failure (ALF). However, clinic...
System for Predicting Neurological Outcomes Following Cardiac Arrest Based on Clinical Predictors Using a Machine Learning Method: The Neurological Outcomes After Cardiac Arrest Method
System for Predicting Neurological Outcomes Following Cardiac Arrest Based on Clinical Predictors Using a Machine Learning Method: The Neurological Outcomes After Cardiac Arrest Method
A multimodal approach may prove effective for predicting clinical outcomes following cardiac arrest (CA). We aimed to deve...
Prognostic Significance of Preoperative Perihematomal Edema in Spontaneous Cerebellar Hemorrhage After Minimally Invasive Surgery
Prognostic Significance of Preoperative Perihematomal Edema in Spontaneous Cerebellar Hemorrhage After Minimally Invasive Surgery
Minimally invasive surgery (MIS), including endoscopic evacuation and minimally invasive catheter (MIC) evacuation, has be...
Palliative General Anesthesia at Terminal Extubation: “Go Gentle into that Good Night”
Palliative General Anesthesia at Terminal Extubation: “Go Gentle into that Good Night”
Withdrawal of life-sustaining treatments in the intensive care unit most often culminates into the discontinuation of mech...
Utility and Value of Movement Recording with Combined EEG-EMG Monitoring in the Intensive Care Unit
Utility and Value of Movement Recording with Combined EEG-EMG Monitoring in the Intensive Care Unit
Continuous electroencephalographic (EEG) monitoring has become a standard of care in several contexts in the intensive car...
Anticoagulant Therapy for Cerebral Venous Sinus Thrombosis: A Propensity Score Matching Study and Inverse Probability Weighting
Anticoagulant Therapy for Cerebral Venous Sinus Thrombosis: A Propensity Score Matching Study and Inverse Probability Weighting
New oral anticoagulants (NOACs) offer potential advantages for patients with cerebral venous sinus thrombosis (CVST). Ther...
Evolution of EEG Findings in Patients with Acute Brain Injury
Evolution of EEG Findings in Patients with Acute Brain Injury
Increasing use of continuous electroencephalography (cEEG) provides the opportunity to observe temporal trends in EEG patt...
Inhibition of C3a/C3aR by SB290157 Attenuates Neuroinflammation via PKC/P38/NLRP3 Signaling Pathway After Intracerebral Hemorrhage
Inhibition of C3a/C3aR by SB290157 Attenuates Neuroinflammation via PKC/P38/NLRP3 Signaling Pathway After Intracerebral Hemorrhage
The C3a/C3aR axis has been shown to play an important role in a variety of neurological diseases. The aim of this study wa...
Neurological Injury in Comatose Patients Following Substance-Use-Related Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study in a Safety Net Hospital
Neurological Injury in Comatose Patients Following Substance-Use-Related Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study in a Safety Net Hospital
Substance-use-related cardiac arrest (SURCA) is a public health crisis, contributing to high mortality and severe neurolog...
Fatal Grade V Immune Effector Cell–Associated Neurotoxicity Syndrome After Chimeric Antigen Receptor T Cell Therapy Leading to Brain Death
Fatal Grade V Immune Effector Cell–Associated Neurotoxicity Syndrome After Chimeric Antigen Receptor T Cell Therapy Leading to Brain Death
Conflicts of Interest The authors declare that they have no conflict of interest...
Eculizumab as a Rescue Therapy in Prolonged Myasthenic Crisis in the Intensive Care Unit: A Case Series
Eculizumab as a Rescue Therapy in Prolonged Myasthenic Crisis in the Intensive Care Unit: A Case Series
Three female patients with AChR + gMG who were intubated due to myasthenic crises (Myasthenia Gravis Foundation of America...
Clinical Consequences of Disproportionate Free Valproate Elevation in Critically Ill Adult Patients: A Multicenter Retrospective Cohort Study
Clinical Consequences of Disproportionate Free Valproate Elevation in Critically Ill Adult Patients: A Multicenter Retrospective Cohort Study
Valproate has a narrow therapeutic index and unpredictable protein binding, and critically ill patients may experience une...
Effects of ‘Head Up’ Prone Position on Transcranial Color Doppler–Based Estimators of Intracranial Pressure in Moderate to Severe Acute Respiratory Distress Syndrome Without Brain Injury: A Cross-Over, Longitudinal, Physiological Study
Effects of ‘Head Up’ Prone Position on Transcranial Color Doppler–Based Estimators of Intracranial Pressure in Moderate to Severe Acute Respiratory Distress Syndrome Without Brain Injury: A Cross-Over, Longitudinal, Physiological Study
Prone positioning is recommended in acute respiratory distress syndrome (ARDS) to ensure adequate gas exchange. However, i...
A Novel, Interpretable Machine Learning Model to Predict Neurological Outcomes Following Venoarterial Extracorporeal Membrane Oxygenation
A Novel, Interpretable Machine Learning Model to Predict Neurological Outcomes Following Venoarterial Extracorporeal Membrane Oxygenation
We used machine learning models incorporating rich electronic medical record (EMR) data to predict neurological outcomes a...
Aneurysmal Subarachnoid Hemorrhage Risk Assessment Model Identifies Patients for Safe Early Discharge at Day 15-The SAFE-SaH Score
Aneurysmal Subarachnoid Hemorrhage Risk Assessment Model Identifies Patients for Safe Early Discharge at Day 15-The SAFE-SaH Score
Patients with aneurysmal subarachnoid hemorrhage (aSAH) are often hospitalized for 21 days after aneurysm rupture due to t...
Which Intravenous Isotonic Fluid Offers Better Outcomes for Patients with a Brain Injury?
Which Intravenous Isotonic Fluid Offers Better Outcomes for Patients with a Brain Injury?
Administering intravenous fluids is a common therapy for critically ill patients. Isotonic crystalloid solutions, such as ...
Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis
Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis
Factor Xa inhibitors (FXaI) are increasingly used for anticoagulation therapy, yet their association with intracranial hem...
Contribution of an Automatic Algorithm for Quantifying the Volume of Aneurysmal Subarachnoid Hemorrhage to the Evaluation of the Risk of Occurrence of Delayed Cerebral Ischemia: A Cohort Study
Contribution of an Automatic Algorithm for Quantifying the Volume of Aneurysmal Subarachnoid Hemorrhage to the Evaluation of the Risk of Occurrence of Delayed Cerebral Ischemia: A Cohort Study
This study focuses on aneurysmal subarachnoid hemorrhage (aSAH) with a high risk of delayed cerebral ischemia (DCI) and ac...
Liberalization of the Systemic Glucose Management is Associated with a Reduced Frequency of Neuroglucopenia in Subarachnoid Hemorrhage Patients: An Observational Cohort Study
Liberalization of the Systemic Glucose Management is Associated with a Reduced Frequency of Neuroglucopenia in Subarachnoid Hemorrhage Patients: An Observational Cohort Study
Pathologically low brain glucose levels, referred to as neuroglucopenia, are associated with unfavorable outcomes in neuro...
Acute Traumatic Coma Awakening Induced by Median Nerve Electrical Stimulation: A Systematic Review and Meta-Analysis
Acute Traumatic Coma Awakening Induced by Median Nerve Electrical Stimulation: A Systematic Review and Meta-Analysis
Traumatic brain injury (TBI) is widely recognized as a major cause of death and disability. Optimizing recovery from coma ...
Iodine-Based Dual-Energy Computed Tomography After Mechanical Thrombectomy Predicts Secondary Neurologic Decline from Cerebral Edema After Severe Stroke
Iodine-Based Dual-Energy Computed Tomography After Mechanical Thrombectomy Predicts Secondary Neurologic Decline from Cerebral Edema After Severe Stroke
Patients with severe stroke are at high risk of secondary neurologic decline (ND) from the development of malignant cerebr...
Continuous Blood Pressure Indices During the First 72 Hours and Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage
Continuous Blood Pressure Indices During the First 72 Hours and Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage
Management of intracerebral hemorrhage (ICH) is challenged by limited therapeutic options and a complex relationship betwe...
Ethically Translating Advanced Neurotechnologies for Disorders of Consciousness: A Survey of Clinicians’ Perspectives
Ethically Translating Advanced Neurotechnologies for Disorders of Consciousness: A Survey of Clinicians’ Perspectives
Although evaluation of disorders of consciousness (DoC) following brain injury has traditionally relied on bedside behavio...
Intracranial Pressure Thresholds for Cerebral Autoregulation Impairment: Age-Stratified Analysis of Ultra-Low-Frequency Pressure Reactivity Index (UL-PRx) in Traumatic Brain Injury
Intracranial Pressure Thresholds for Cerebral Autoregulation Impairment: Age-Stratified Analysis of Ultra-Low-Frequency Pressure Reactivity Index (UL-PRx) in Traumatic Brain Injury
The study investigated the effectiveness of low-frequency sampling in detecting alterations in cerebrovascular reactivity ...
Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis
Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis
In intensive care, delirium is frequent, prolongs the stay, increases health care costs, and worsens patient outcome. Seve...
Early Versus Late Initiation of Endovascular Therapy in Patients with Severe Cerebral Venous Sinus Thrombosis
Early Versus Late Initiation of Endovascular Therapy in Patients with Severe Cerebral Venous Sinus Thrombosis
Endovascular therapy (EVT) for severe cerebral venous sinus thrombosis (CVST) is controversial in terms of indication and ...
Risk Factors for Cerebral Vasospasm After Subarachnoid Hemorrhage: A Systematic Review of Observational Studies
Risk Factors for Cerebral Vasospasm After Subarachnoid Hemorrhage: A Systematic Review of Observational Studies
Cerebral vasospasm (CV) following subarachnoid hemorrhage (SAH) remains one of the leading causes of high mortality and po...
Early Burst Suppression Similarity Association with Structural Brain Injury Severity on MRI After Cardiac Arrest
Early Burst Suppression Similarity Association with Structural Brain Injury Severity on MRI After Cardiac Arrest
Identical bursts on electroencephalography (EEG) are considered a specific predictor of poor outcomes in cardiac arrest, b...
Mismatch Negativity and P300 in the Diagnosis and Prognostic Assessment of Coma and Other Disorders of Consciousness
Mismatch Negativity and P300 in the Diagnosis and Prognostic Assessment of Coma and Other Disorders of Consciousness
The objective of this study was to investigate the value of mismatch negativity (MMN) and P300 event-related potentials fo...
Development and Validation of a Risk Score for Predicting ICU Admission in Adults with New-Onset Encephalitis
Development and Validation of a Risk Score for Predicting ICU Admission in Adults with New-Onset Encephalitis
Timely intensive care unit (ICU) admission for patients with encephalitis is associated with better prognosis. Therefore, ...
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