Neurological Injury in Comatose Patients Following Substance-Use-Related Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study in a Safety Net Hospital

Ahmad F, Ciewski J, Rossen L, Sutton P. Provisional Drug Overdose Death Counts. National Center for Health Statistics; 2024.

Friedman J, Beletsky L, Schriger DL. Overdose-Related Cardiac Arrests Observed by Emergency Medical Services During the US COVID-19 Epidemic. JAMA Psychiat. 2021;78(5):562–4. https://doi.org/10.1001/jamapsychiatry.2020.4218.

Article  Google Scholar 

Dezfulian C, Orkin AM, Maron BA, et al. Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses: A Scientific Statement From the American Heart Association. Circulation. 2021;143(16):e836–70. https://doi.org/10.1161/CIR.0000000000000958.

Article  PubMed  Google Scholar 

Black JC, Bau GE, Iwanicki JL, Dart RC. Association of Medical Stimulants With Mortality in the US From 2010 to 2017. JAMA Intern Med. 2021;181(5):707–9. https://doi.org/10.1001/jamainternmed.2020.7850.

Article  PubMed  PubMed Central  Google Scholar 

Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep. 2018;67(5152). https://doi.org/10.15585/mmwr.mm675152e1

Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN. The Burden of Opioid-Related Mortality in the United States. JAMA Netw Open. 2018;1(2): e180217. https://doi.org/10.1001/jamanetworkopen.2018.0217.

Article  PubMed  PubMed Central  Google Scholar 

Elmer J, Lynch MJ, Kristan J, et al. Recreational drug overdose-related cardiac arrests: Break on through to the other side. Resuscitation. 2015;89:177–81. https://doi.org/10.1016/j.resuscitation.2015.01.028.

Article  PubMed  PubMed Central  Google Scholar 

Kulpanowski AM, Copen WA, Hancock BL, et al. Severe cerebral edema in substance-related cardiac arrest patients. Resuscitation. 2022;173:103–11. https://doi.org/10.1016/j.resuscitation.2022.01.033.

Article  PubMed  PubMed Central  Google Scholar 

Yogeswaran V, Drucker C, Kume K, et al. Presentation and Outcomes of Adults With Overdose-Related Out-of-Hospital Cardiac Arrest. JAMA Netw Open. 2023;6(11): e2341921. https://doi.org/10.1001/jamanetworkopen.2023.41921.

Article  PubMed  PubMed Central  Google Scholar 

Katz AZ, Grossestreuer AV, Gaieski DF, Abella BS, Kumar V, Perrone J. Outcomes of patients resuscitated from cardiac arrest in the setting of drug overdose. Resuscitation. 2015;94:23–7. https://doi.org/10.1016/j.resuscitation.2015.06.015.

Article  PubMed  Google Scholar 

Ormseth CH, Maciel CB, Zhou SE, et al. Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose. Resuscitation. 2019;139:9–16. https://doi.org/10.1016/j.resuscitation.2019.04.004.

Article  PubMed  Google Scholar 

Koller AC, Salcido DD, Callaway CW, Menegazzi JJ. Resuscitation characteristics and outcomes in suspected drug overdose-related out-of-hospital cardiac arrest. Resuscitation. 2014;85(10):1375–9. https://doi.org/10.1016/j.resuscitation.2014.05.036.

Article  PubMed  PubMed Central  Google Scholar 

Orkin AM, Zhan C, Buick JE, et al. Out-of-hospital cardiac arrest survival in drug-related versus cardiac causes in Ontario: A retrospective cohort study. PLoS ONE. 2017;12(4): e0176441. https://doi.org/10.1371/journal.pone.0176441.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salcido DD, Torres C, Koller AC, et al. Regional incidence and outcome of out-of-hospital cardiac arrest associated with overdose. Resuscitation. 2016;99:13–9. https://doi.org/10.1016/j.resuscitation.2015.11.010.

Article  PubMed  Google Scholar 

Elmer J, Torres C, Aufderheide TP, et al. Association of early withdrawal of life-sustaining therapy for perceived neurological prognosis with mortality after cardiac arrest. Resuscitation. 2016;102:127–35. https://doi.org/10.1016/j.resuscitation.2016.01.016.

Article  PubMed  PubMed Central  Google Scholar 

Epic. Published online 2024.

Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)–a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81. https://doi.org/10.1016/j.jbi.2008.08.010.

Article  PubMed  Google Scholar 

Hirsch LJ, Fong MWK, Leitinger M, et al. American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2021 Version. J Clin Neurophysiol. 2021;38(1):1–29. https://doi.org/10.1097/WNP.0000000000000806.

Article  PubMed  PubMed Central  Google Scholar 

Nolan JP, Sandroni C, Böttiger BW, et al. European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care. Intensive Care Med. 2021;47(4):369–421. https://doi.org/10.1007/s00134-021-06368-4.

Article  PubMed  PubMed Central  Google Scholar 

IBM SPSS Statistics for Windows. Published online 2020.

RStudio. Published online 2018.

Shekhar AC, Nathanson BH, Mader TJ, Coute RA. Cardiac Arrest Following Drug Overdose in the United States: An Analysis of the Cardiac Arrest Registry to Enhance Survival. J Am Heart Assoc. 2024;13(3): e031245. https://doi.org/10.1161/JAHA.123.031245.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang RC, Montoy JCC, Rodriguez RM, Menegazzi JJ, Lacocque J, Dillon DG. Trends in presumed drug overdose out-of-hospital cardiac arrests in San Francisco, 2015–2023. Resuscitation. 2024;198: 110159. https://doi.org/10.1016/j.resuscitation.2024.110159.

Article  PubMed  PubMed Central  Google Scholar 

Liu X, Carney PR, Bussing R, Segal R, Cottler LB, Winterstein AG. Stimulants Do Not Increase the Risk of Seizure-Related Hospitalizations in Children with Epilepsy. J Child Adolesc Psychopharmacol. 2018;28(2):111–6. https://doi.org/10.1089/cap.2017.0110.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elder HJ, Varshneya NB, Walentiny DM, Beardsley PM. Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner. Drug Alcohol Depend. 2023;243: 109740. https://doi.org/10.1016/j.drugalcdep.2022.109740.

Article  CAS  PubMed  Google Scholar 

National Institute on Drug Abuse. Drug Overdose Deaths: Facts and Figures. National Institute on Drug Abuse. August 21, 2024. Accessed October 13, 2024. https://nida.nih.gov/research-topics/trends-statistics/overdose-death-rates#Fig7

Smith G, Beger S, Vadeboncoeur T, et al. Trends in overdose-related out-of-hospital cardiac arrest in Arizona. Resuscitation. 2019;134:122–6. https://doi.org/10.1016/j.resuscitation.2018.10.019.

Article  PubMed  Google Scholar 

Arctaedius I, Levin H, Larsson M, et al. 2021 European Resuscitation Council/European Society of Intensive Care Medicine Algorithm for Prognostication of Poor Neurological Outcome After Cardiac Arrest-Can Entry Criteria Be Broadened? Crit Care Med. 2024;52(4):531–41. https://doi.org/10.1097/CCM.0000000000006113.

Article  PubMed  Google Scholar 

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