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Assessment of anticoagulant safety and coagulation analysis in mice using the VETSCAN VSpro analyzer
Assessment of anticoagulant safety and coagulation analysis in mice using the VETSCAN VSpro analyzer
Animal models of thrombosis play a critical role in research, helping us understand the mechanisms of hemostasis and throm...
Exploring the causal inference of inflammatory bowel disease and ischemic stroke: a bidirectional two-sample Mendelian randomization study
Exploring the causal inference of inflammatory bowel disease and ischemic stroke: a bidirectional two-sample Mendelian randomization study
Growing evidence suggests inflammatory bowel disease (IBD) is linked to ischemic stroke (IS); however, the results are inc...
Efficacy and safety of anti-Xa direct oral anticoagulants vs. warfarin in patients homozygous for Factor V Leiden and prothrombin G20210A mutations
Efficacy and safety of anti-Xa direct oral anticoagulants vs. warfarin in patients homozygous for Factor V Leiden and prothrombin G20210A mutations
Factor V Leiden (FVL) and prothrombin G20210A mutation (PGM) are the most common types of inherited thrombophilia, predisp...
Hydrogen sulphide alleviates platelet dysfunction in patients with type 2 diabetes
Hydrogen sulphide alleviates platelet dysfunction in patients with type 2 diabetes
Wang L, Peng W, Zhao Z, Zhang M, Shi Z, Song Z, Zhang X, Li C, Huang Z, Sun X, Wang L, Zhou M, Wu J, Wang Y (2021) Prevale...
Renal function and adverse clinical events in anticoagulated patients with atrial fibrillation: insights from the GLORIA-AF Registry Phase III
Renal function and adverse clinical events in anticoagulated patients with atrial fibrillation: insights from the GLORIA-AF Registry Phase III
Renal function, assessed by creatinine clearance (CrCl), affects the efficacy and safety of oral anticoagulant (OAC) thera...
Predictors of futile recanalization after intravenous thrombolysis in stroke patients transferred for endovascular treatment
Predictors of futile recanalization after intravenous thrombolysis in stroke patients transferred for endovascular treatment
Some patients with large vessel occlusion (LVO) achieve insufficient clinical improvement (futile recanalization, FR) afte...
The impact of thrombophilia on in-hospital outcomes in patients with acute coronary syndrome: insights from the United States National Inpatient Sample
The impact of thrombophilia on in-hospital outcomes in patients with acute coronary syndrome: insights from the United States National Inpatient Sample
The prevalence of thrombophilia among patients who are hospitalized with acute coronary syndrome (ACS) and whether the con...
Apixaban versus warfarin for treatment of venous thromboembolism in patients with severe renal impairment: a multicenter study
Apixaban versus warfarin for treatment of venous thromboembolism in patients with severe renal impairment: a multicenter study
Limited evidence exists regarding the use of factor Xa inhibitors for the treatment of venous thromboembolism (VTE) in pat...
Unveiling the complexities of catheter-related thrombosis: risk factors, preventive strategies, and management
Unveiling the complexities of catheter-related thrombosis: risk factors, preventive strategies, and management
Catheter-related deep venous thrombosis (CR-DVT) is a common complication of central venous catheters, however optimal pro...
Comparison of the procoagulant activity between extracellular vesicles obtained from cellular monolayers and spheroids
Comparison of the procoagulant activity between extracellular vesicles obtained from cellular monolayers and spheroids
Tissue factor (TF) is the main activator of blood coagulation and is associated with thrombosis and tumor progression. It ...
Immune checkpoint inhibitors and myocardial infarction
Immune checkpoint inhibitors and myocardial infarction
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy since their first approval in 2011. By unleashing t...
Significant attenuation of fully automated thrombin generation in newly diagnosed multiple myeloma patients after induction therapy
Significant attenuation of fully automated thrombin generation in newly diagnosed multiple myeloma patients after induction therapy
Nearly 10% of newly diagnosed multiple myeloma (NDMM) patients develop a venous thromboembolism (VTE) episode during their...
Incidence of arterial and venous thromboembolism in cancer patients- insights from more than 5,000,000 patients
Incidence of arterial and venous thromboembolism in cancer patients- insights from more than 5,000,000 patients
The reported incidence of arterial thromboembolism (ATE) and venous thromboembolism (VTE) after cancer varies. A meta-anal...
Tissue factor pathway inhibitor levels and atherothrombotic events in patients with chronic kidney disease or diabetes
Tissue factor pathway inhibitor levels and atherothrombotic events in patients with chronic kidney disease or diabetes
Increased tissue factor pathway inhibitor (TFPI) has been associated with cardiovascular disease (CVD). We aim to evaluate...
Predictors of venous thromboembolic events in hospitalized patients with COVID-19
Predictors of venous thromboembolic events in hospitalized patients with COVID-19
COVID-19 is associated with an increased risk of venous thromboembolism (VTE) in hospitalized patients. Although prior stu...
Recanalization is more important than procedure time on outcome of thrombectomy in acute vertebrobasilar artery occlusion
Recanalization is more important than procedure time on outcome of thrombectomy in acute vertebrobasilar artery occlusion
Longer procedure time (PT) predicts worse prognosis after endovascular treatment (EVT) in acute vertebrobasilar artery occ...
Intravenous thrombolysis with tenecteplase versus alteplase in acute ischemic stroke tandem occlusions: a systematic review and meta-analysis of current available literature
Intravenous thrombolysis with tenecteplase versus alteplase in acute ischemic stroke tandem occlusions: a systematic review and meta-analysis of current available literature
Tandem occlusions, characterized by the simultaneous occurrence of both extracranial and ipsilateral intracranial arterial...
Management of thrombocytopenia and anticoagulant therapy in patients with hematological malignancy on chemotherapy: a binational prospective study (TAT study)
Management of thrombocytopenia and anticoagulant therapy in patients with hematological malignancy on chemotherapy: a binational prospective study (TAT study)
Anticoagulant use in patients with hematological malignancies treated on intensive chemotherapy represents a management ch...
New interest in fibrinogen as an ischemic risk factor
New interest in fibrinogen as an ischemic risk factor
Platelet-fibrin clot formation is a key process in acute arterial thrombosis. The relationship between thrombin-induced pl...
Enhanced thrombin generation induced by extracellular vesicles from severe COVID−19 cases
Enhanced thrombin generation induced by extracellular vesicles from severe COVID−19 cases
Authors and AffiliationsUniversity of Sao Paulo Medical School, Sao Paulo, BrazilBárbara Gomes Barion & Thaís Dourado ...
Growth differentiation factor-15 predicts all-cause death and major adverse cardiovascular events in patients with coronary heart disease: a prospective cohort study
Growth differentiation factor-15 predicts all-cause death and major adverse cardiovascular events in patients with coronary heart disease: a prospective cohort study
The prognostic value of growth differentiation factor-15 (GDF-15) in predicting long-term adverse outcomes in coronary hea...
Construction and validation of a nomogram prediction model for the catheter-related thrombosis risk of central venous access devices in patients with cancer: a prospective machine learning study
Construction and validation of a nomogram prediction model for the catheter-related thrombosis risk of central venous access devices in patients with cancer: a prospective machine learning study
Central venous access devices (CVADs) are integral to cancer treatment. However, catheter-related thrombosis (CRT) poses a...
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
• Hospitalized patients may exhibit discordance in aPTT and anti-Xa activities while on UFH. • In this study, ...
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
In this study, we compared whether there was any difference between the ASTRAL(Acute Stroke Registry and Analysis of Lausa...
Risk of venous thromboembolism after discontinuing prophylactic or therapeutic anticoagulation in patients with haematologic malignancies because of thrombocytopenia
Risk of venous thromboembolism after discontinuing prophylactic or therapeutic anticoagulation in patients with haematologic malignancies because of thrombocytopenia
Although the rates of thrombocytopenia in patients with hematologic malignancies are well known, clinical reports of patie...
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
Oxidized low-density lipoprotein (ox-LDL)-associated endothelial dysfunction is a critical factor in the initiation and pr...
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Accurate risk stratification in acute intermediate-risk pulmonary embolism (PE) is essential. Current prediction scores la...
3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors
3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors
Multiple agents exist for the reversal of oral Factor Xa inhibitor (FXa) associated bleeding, including Coagulation FXa Re...
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Factor XIIa (FXIIa) is a plasma serine protease within the contact activation pathway. Inhibiting FXIIa could offer a viab...
Cerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study
Cerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study
Nearly one fifth of patients with venous thromboembolism (VTE) have cancer. When both of these conditions occur, especiall...
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