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Typing Brucella Species by MALDI-TOF Mass Spectrometry Combined with Machine Learning
Typing Brucella Species by MALDI-TOF Mass Spectrometry Combined with Machine Learning
Brucellosis is a highly infectious anthropozoonotic disease caused by the genus Brucella, which is the pathogenic bacteria...
On-Line Monitoring of Guizhi Fuling Capsules and Tablets Dissolution Behavior Using Near-Infrared Spectroscopy Combined with Chemometrics
On-Line Monitoring of Guizhi Fuling Capsules and Tablets Dissolution Behavior Using Near-Infrared Spectroscopy Combined with Chemometrics
To validate the feasibility of using near-infrared (NIR) spectroscopy for real-time monitoring of multiple active pharmace...
Direct in situ Measurement of Electrocatalytic Carbon Dioxide Reduction Properties using Scanning Electrochemical Microscopy
Direct in situ Measurement of Electrocatalytic Carbon Dioxide Reduction Properties using Scanning Electrochemical Microscopy
One fundamental question facing electrocatalytic CO2 reduction reaction (CO2RR) is how to identify and correlate the local...
Efficient Determination of Se(IV) with a Glassy Carbon Bismuth Film Electrode: Overcoming Cu(II) Interference
Efficient Determination of Se(IV) with a Glassy Carbon Bismuth Film Electrode: Overcoming Cu(II) Interference
The development of a simple, fast, and sensitive method for Se(IV) determination is detailed in the present work. Experime...
DNA Scaffold-Enhanced Hybrid Chain Reaction for Molecular Diagnosis of miRNAs
DNA Scaffold-Enhanced Hybrid Chain Reaction for Molecular Diagnosis of miRNAs
The hybridization chain reaction (HCR) is a widely used nucleic acid amplification technique that is essential for gene ex...
Recent Advances in Molybdenum Disulfide-Based Nanozymes for Sensing Applications
Recent Advances in Molybdenum Disulfide-Based Nanozymes for Sensing Applications
With the development of nanotechnology, “nanozymes”, a kind of nanomaterials with high enzyme-like activity, h...
Multichannel Sensor Arrays Based on Surface-Engineered Fluorescent Metal Clusterzymes for Differential Sensing of Cancer Cells
Multichannel Sensor Arrays Based on Surface-Engineered Fluorescent Metal Clusterzymes for Differential Sensing of Cancer Cells
Rapid and effective differentiation of cancerous cells is essential for early diagnosis and treatment of tumors. Here, a m...
Electrochemical Biosensor Based on Lactate Oxidase Mimic Activity of CoN/rGO for Lactate Detection
Electrochemical Biosensor Based on Lactate Oxidase Mimic Activity of CoN/rGO for Lactate Detection
The preparation of a sensitive electrochemical biosensor for lactate determination, devoid of lactate enzyme, is achieved ...
Modification of Microporous Organic Network with Amino Acid for HILIC/RPLC Mixed-Mode High-Performance Liquid Chromatography
Modification of Microporous Organic Network with Amino Acid for HILIC/RPLC Mixed-Mode High-Performance Liquid Chromatography
Microporous organic network (MON) has emerged as efficient stationary phases for high-performance liquid chromatographic (...
High-Sensitivity Detection of Tobacco Mosaic Virus RNA Based on a Ring-Opening Polymerization Fluorescent Biosensor
High-Sensitivity Detection of Tobacco Mosaic Virus RNA Based on a Ring-Opening Polymerization Fluorescent Biosensor
This study employs an N-carboxyanhydride ring-opening polymerization (NCA ROP) signal amplification strategy to construct ...
Affinity Capture Coupled with Nano-Electrospray Ionization-Mass Spectrometry for Rapid Detection of 25-hydroxyvitamin D3 in Serum
Affinity Capture Coupled with Nano-Electrospray Ionization-Mass Spectrometry for Rapid Detection of 25-hydroxyvitamin D3 in Serum
Due to the important role of vitamin D in metabolism, developing a method for rapid and high-throughput analysis of vitami...
Lipid Visualization of 3D-hetero-type Multicellular Spheroids During the Spatiotemporal Progression of Pancreatic Cancer
Lipid Visualization of 3D-hetero-type Multicellular Spheroids During the Spatiotemporal Progression of Pancreatic Cancer
Pancreatic cancer has a tough early diagnosis and awful prognosis among all human cancers. Tumor heterogeneity can hinder ...
Auto-Fluorescence Cellulose Paper Based on High Affinity of Sodium Lignosulfonate for Microfluidic Detection Platform
Auto-Fluorescence Cellulose Paper Based on High Affinity of Sodium Lignosulfonate for Microfluidic Detection Platform
The auto-fluorescence of cellulose filter paper has long been a bottleneck for its utilization as a solid-phase fluorescen...
Optimization and Implementation of Spectrophotometric and Fluorimetric Methodologies to Evaluate Pancreatic Lipase Inhibitory Using Chalcones: A Comparative Study
Optimization and Implementation of Spectrophotometric and Fluorimetric Methodologies to Evaluate Pancreatic Lipase Inhibitory Using Chalcones: A Comparative Study
This study aimed to identify new compounds capable of decreasing pancreatic lipase (PL) catalytic activity. A panel of str...
Multiway Analysis of the Electrochemical Oxidation Pathway of a Lignin Model Compound, Benzyl Phenyl Ether, with Chemometrics
Multiway Analysis of the Electrochemical Oxidation Pathway of a Lignin Model Compound, Benzyl Phenyl Ether, with Chemometrics
The economics of electrochemical depolymerization of lignin are most likely unfavorable without having control over the ox...
Separation of Rare Earth Elements Using Aromatic Sulfonic Acid-Modified Silica Chromatographic Stationary Phase
Separation of Rare Earth Elements Using Aromatic Sulfonic Acid-Modified Silica Chromatographic Stationary Phase
Ion exchange chromatography (IEC) is one of the essential methods to separate rare earth elements (REEs), which relies on ...
Tellurium Speciation via Frontal Chromatography ICP-MS: An Innovative and Effective Approach for the Ultratrace Detection in Environmental Matrices
Tellurium Speciation via Frontal Chromatography ICP-MS: An Innovative and Effective Approach for the Ultratrace Detection in Environmental Matrices
The increasing use of tellurium (Te) in electronics and renewable energy technologies has elevated its environmental conce...
Chemical Proteomics Unraveling the Contribution of Covalent Protein Modifications to Antidepressant Effects of Ketamine
Chemical Proteomics Unraveling the Contribution of Covalent Protein Modifications to Antidepressant Effects of Ketamine
Ketamine is recognized for its rapid-onset and longer-term antidepressant actions, but the molecular mechanisms underlying...
Enhanced Selectivity of Colorimetric Molecularly Imprinted Polymer Paper-based Sensor for Detection of Bisphenol-A in Plastic Bottles
Enhanced Selectivity of Colorimetric Molecularly Imprinted Polymer Paper-based Sensor for Detection of Bisphenol-A in Plastic Bottles
This research has developed a paper-based sensor incorporating molecularly imprinted polymer (MIP) technology for the dete...
Rapid and Sensitive Biosensing of Salmonella Using Mechanical Step Rotation and Gold@platinum Nanozymatic Amplification
Rapid and Sensitive Biosensing of Salmonella Using Mechanical Step Rotation and Gold@platinum Nanozymatic Amplification
Inspired by ballpoint pen, an optical biosensor is developed for detection of Salmonella using a mechanical step rotator w...
Paper Analytical Device for the Colourimetric Detection of Alkaline Phosphatase in Serum and Saliva
Paper Analytical Device for the Colourimetric Detection of Alkaline Phosphatase in Serum and Saliva
A paper analytical device (PAD) was developed for the colourimetric estimation of alkaline phosphatase (ALP). ALP catalyze...
Multifunctional Peptide-Melanin Hybrid Nanodots with Robust Anti-Cutaneous Photoaging Activity
Multifunctional Peptide-Melanin Hybrid Nanodots with Robust Anti-Cutaneous Photoaging Activity
Skin aging is a systematic and complex process, mainly including intrinsic aging caused by time change and extrinsic aging...
A High-Performance Electrochemical Analysis Platform for Ultrasensitive Detection of HTLV-1 DNA: Integrating Cascade Signal Amplification with λ-Exonuclease-Assisted Target Recycling and Enzyme Catalysis
A High-Performance Electrochemical Analysis Platform for Ultrasensitive Detection of HTLV-1 DNA: Integrating Cascade Signal Amplification with λ-Exonuclease-Assisted Target Recycling and Enzyme Catalysis
Human T-cell lymphophilic virus type 1 (HTLV-1), the known retrovirus causing cancer in humans, is closely associated with...
Cannabinoid Modulation of Monoamine Levels in Mouse Brain: Unveiling Neurochemical Dynamics through an Innovative High-performance Liquid Chromatography-Fluorescence Detection Bioanalysis
Cannabinoid Modulation of Monoamine Levels in Mouse Brain: Unveiling Neurochemical Dynamics through an Innovative High-performance Liquid Chromatography-Fluorescence Detection Bioanalysis
Homeostasis of monoaminergic pathways is compromised in aging and neurodegenerative/neurological diseases such as Alzheime...
Hydrophilic Chitosan/Covalent Organic Framework Composites for Efficient Solid-Phase Microextraction of Polar Phenolic Compounds Prior to Gas Chromatography: Mass Spectrometry Analysis
Hydrophilic Chitosan/Covalent Organic Framework Composites for Efficient Solid-Phase Microextraction of Polar Phenolic Compounds Prior to Gas Chromatography: Mass Spectrometry Analysis
Covalent organic frameworks (COFs) have been widely used to prepare solid-phase microextraction (SPME) coatings due to the...
Dual-Mode Colorimetric and Fluorescent Detection of Tumor Cells Based on Gold Nanoparticles-Loaded Phosphine Covalent Organic Frameworks
Dual-Mode Colorimetric and Fluorescent Detection of Tumor Cells Based on Gold Nanoparticles-Loaded Phosphine Covalent Organic Frameworks
Circulating tumor cells (CTCs) are important markers for cancer. The part of tumor cells that are detached from the primar...
A Highly Sensitive Electrochemical Aptasensor for Kanamycin: Leveraging RecJf Exonuclease-Assisted Target Recycling and Hybridization Chain Reaction Signal Amplification
A Highly Sensitive Electrochemical Aptasensor for Kanamycin: Leveraging RecJf Exonuclease-Assisted Target Recycling and Hybridization Chain Reaction Signal Amplification
A highly sensitive electrochemical aptasensor was developed for the detection of kanamycin, employing a DNA signal amplifi...
CRISPR-Cas12a Coupled with Universal Dual-mode Fluorescent Nanoparticles Platform for HPV Nucleic Acid Detection
CRISPR-Cas12a Coupled with Universal Dual-mode Fluorescent Nanoparticles Platform for HPV Nucleic Acid Detection
Cervical cancer is a prevalent gynecological malignancy, with approximately 90% of cases attributed to human papillomaviru...
Recent Progress in the Construction of Chiral Plasmonic Gold Nanostructures and Their Biochemical Sensing Applications
Recent Progress in the Construction of Chiral Plasmonic Gold Nanostructures and Their Biochemical Sensing Applications
Chirality, as the asymmetric property of nature, cannot fit its mirror image by translation or rotation. It is widespread ...
Polydopamine (PDA) Functionalized Eutectic Gallium–Indium (EGaIn) Nanoparticles as a Distortable Fluorescent Sensor for Pb2+ Detection
Polydopamine (PDA) Functionalized Eutectic Gallium–Indium (EGaIn) Nanoparticles as a Distortable Fluorescent Sensor for Pb2+ Detection
Fluorescent nanoparticles offer promising applications for bioimaging due to their exceptional attributes, including heigh...
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