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Spatial FAP Expression as Detected by  Ga-FAPI-46 Identifies Myofibroblasts Beyond the Infarct Scar After Reperfusion
Spatial FAP Expression as Detected by  Ga-FAPI-46 Identifies Myofibroblasts Beyond the Infarct Scar After Reperfusion
Myocardial infarction (MI) triggers complex cellular responses essential for tissue repair and remodeling, including myofi...
Dual Targeting of Neuropilin-1 and Glucose Transporter for Efficient Fluorescence Imaging of Cancer
Dual Targeting of Neuropilin-1 and Glucose Transporter for Efficient Fluorescence Imaging of Cancer
Early diagnosis and complete resection of cancer are pivotal for enhancing patient survival rates and prognosis. However, ...
Development of Anti-CEA C2 Domain-Deleted Antibody (M5A∆C2) for the PET Imaging of Colorectal Cancer
Development of Anti-CEA C2 Domain-Deleted Antibody (M5A∆C2) for the PET Imaging of Colorectal Cancer
Recombinant antibody fragments represent a novel class of in vivo biological immunoPET imaging agents. This study develope...
Development of a CT-less SPECT Acquisition Protocol for Kidney Dosimetry in Lu-PSMA-617 Radioligand Therapy
Development of a CT-less SPECT Acquisition Protocol for Kidney Dosimetry in Lu-PSMA-617 Radioligand Therapy
Targeted radioligand therapy of metastatic castration-resistant prostate cancer (mCRPC) with 177Lu-PSMA (RLT) requires suf...
Imaging Cell Surface Plectin in PDAC Patients – A First-In-Human Phase 0 Study Report
Imaging Cell Surface Plectin in PDAC Patients – A First-In-Human Phase 0 Study Report
Plectin is traditionally an intracellular cytoskeletal protein that maintains cell structure and stability. However, we an...
Synthesis and Construction of I-124 Labeled Small Molecular Probe for Noninvasive PET Imaging of CAIX Expression
Synthesis and Construction of I-124 Labeled Small Molecular Probe for Noninvasive PET Imaging of CAIX Expression
Carbonic anhydrase IX (CAIX) which is high expression in the most of hypoxic tumor than normal tissue, promoting the growt...
Assessment of Heat Stroke-Induced Brain Injury: A Preclinical Study with a Rat Model Using F-FDG Brain PET
Assessment of Heat Stroke-Induced Brain Injury: A Preclinical Study with a Rat Model Using F-FDG Brain PET
Heat stroke is the most serious heat-related illness and is recognized as a worldwide public concern as global temperature...
Physiological Uptake of Ga-FAPI-04 in Female Reproductive System
Physiological Uptake of Ga-FAPI-04 in Female Reproductive System
Since the avid uptake of 68Ga-labeled fibroblast activation protein inhibitor (68Ga-FAPI-04) observed in female reproducti...
Species-Specific Hepatic Uptake of [Cu]Cu-EOB-NOTA, A Newly Designed Hepatospecific PET Agent
Species-Specific Hepatic Uptake of [Cu]Cu-EOB-NOTA, A Newly Designed Hepatospecific PET Agent
Measuring hepatic flux rates of transportable substrates has the potential for assessing liver function. PET imaging of a ...
Radiomic Analysis of Striatal [F]FDOPA PET Imaging in Patients with Psychosis for the Identification of Antipsychotic Response
Radiomic Analysis of Striatal [F]FDOPA PET Imaging in Patients with Psychosis for the Identification of Antipsychotic Response
Schizophrenia (SCZ) is a severe psychiatric disorder marked by abnormal dopamine synthesis, measurable through [18F]FDOPA ...
Development of 52Mn Labeled Trastuzumab for Extended Time Point PET Imaging of HER2
Development of 52Mn Labeled Trastuzumab for Extended Time Point PET Imaging of HER2
Due to their long circulation time in the blood, monoclonal antibodies (mAbs) such as trastuzumab, are usually radiolabele...
Zirconium- 89 Labeled Antibody K1-70 for PET Imaging of Thyroid-stimulating Hormone Receptor Expression in Thyroid Cancer
Zirconium- 89 Labeled Antibody K1-70 for PET Imaging of Thyroid-stimulating Hormone Receptor Expression in Thyroid Cancer
Thyroid-stimulating hormone receptor (TSHR) is a G-protein coupled receptor that is highly expressed on benign and maligna...
Administration of Aripiprazole Alleviates Memory Impairment and Restores Damaged Glutamatergic System in 5xFAD Mice
Administration of Aripiprazole Alleviates Memory Impairment and Restores Damaged Glutamatergic System in 5xFAD Mice
Many patients with Alzheimer's disease (AD) also have psychosis, and it has been reported that these patients have mor...
Volume-Based Quantitative Measurement of [18F]AlF-NOTA-FAPI-04 PET/CT Uptake Reflects the Disease Activity of IgG4-Related Disease
Volume-Based Quantitative Measurement of [18F]AlF-NOTA-FAPI-04 PET/CT Uptake Reflects the Disease Activity of IgG4-Related Disease
To investigate the potential utility of quantitative parameters obtained by 18F-fibroblast activation protein inhibitor po...
Cryo-Fluorescence Tomography as a Tool for Visualizing Whole-Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers
Cryo-Fluorescence Tomography as a Tool for Visualizing Whole-Body Inflammation Using Perfluorocarbon Nanoemulsion Tracers
We explore the use of intravenously delivered fluorescent perfluorocarbon (PFC) nanoemulsion tracers and multi-spectral cr...
Differentiation Between Responders and Non-Responders to Antibiotic Treatment in Mice Using 18F-Fluorodeoxysorbitol/PET
Differentiation Between Responders and Non-Responders to Antibiotic Treatment in Mice Using 18F-Fluorodeoxysorbitol/PET
Bacterial infection causes significant mortality and morbidity worldwide despite the availability of antibiotics. Differen...
In Vivo Detection of Lymph Nodes Metastasis of ESCC Using CXCR4-Targeted Tracer [64Cu]Cu-NOTA-CP01
In Vivo Detection of Lymph Nodes Metastasis of ESCC Using CXCR4-Targeted Tracer [64Cu]Cu-NOTA-CP01
Esophageal squamous cell carcinoma (ESCC) frequently exhibits skip metastasis to lymph nodes; however, non-invasive imagin...
Optimisation of Animal Handing and Timing of 2-deoxy-2-[18F]fluoro-D-glucose PET Tumour Imaging in Mice
Optimisation of Animal Handing and Timing of 2-deoxy-2-[18F]fluoro-D-glucose PET Tumour Imaging in Mice
In humans, 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) tumour-to-background contrast continues to increase long after a typ...