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Identification and validation of autophagy-related genes in sepsis based on bioinformatics studies
Identification and validation of autophagy-related genes in sepsis based on bioinformatics studies
We identified 14 key genes associated with mitochondrial autophagy in sepsis through differential analysis of the dataset ...
Genomic and proteomic characterization of four novel Schitoviridae family phages targeting uropathogenic Escherichia coli strain
Genomic and proteomic characterization of four novel Schitoviridae family phages targeting uropathogenic Escherichia coli strain
Escherichia coli-associated urinary tract infections (UTIs) are among the most prevalent bacterial infections in humans. T...
Increase of VEGF and Fibronectin expression and ultrastructural alterations of intercellular junctions in a swab negative patient after SARS-COV-2 infection
Increase of VEGF and Fibronectin expression and ultrastructural alterations of intercellular junctions in a swab negative patient after SARS-COV-2 infection
SARS-CoV-2 infection has been responsible of COrona VIrus Disease (COVID-19) pandemia and can cause a variety of symptoms ...
Epidemiology and genetic diversity of human respiratory syncytial virus in Belgium between 2011 and 2019
Epidemiology and genetic diversity of human respiratory syncytial virus in Belgium between 2011 and 2019
Human respiratory syncytial virus (HRSV) is worldwide one of the leading causes of acute respiratory tract infections in y...
Metabolomic alterations in the plasma of patients with various clinical manifestations of COVID-19
Metabolomic alterations in the plasma of patients with various clinical manifestations of COVID-19
The metabolomic profiles of individuals with different clinical manifestations of severe acute respiratory syndrome corona...
Application prospects of the 2BS cell-adapted China fixed rabies virus vaccine strain 2aG4-B40
Application prospects of the 2BS cell-adapted China fixed rabies virus vaccine strain 2aG4-B40
Rabies is a fatal zoonotic disease whose pathogenesis has not been fully elucidated, and vaccination is the only effective...
Application prospects of the 2BS cell-adapted China fixed rabies virus vaccine strain 2aG4-B40
Application prospects of the 2BS cell-adapted China fixed rabies virus vaccine strain 2aG4-B40
Rabies is a fatal zoonotic disease whose pathogenesis has not been fully elucidated, and vaccination is the only effective...
A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China
A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China
Canine enteric coronavirus (CECoV) is a prevalent infectious disease among dogs worldwide, yet its epidemiology in mainlan...
A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China
A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China
Canine enteric coronavirus (CECoV) is a prevalent infectious disease among dogs worldwide, yet its epidemiology in mainlan...
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells
Newborn piglets’ health is seriously threatened by the porcine epidemic diarrhea virus (PEDV), which also has a sign...
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells
Butyrate induces higher host transcriptional changes to inhibit porcine epidemic diarrhea virus strain CV777 infection in porcine intestine epithelial cells
Newborn piglets’ health is seriously threatened by the porcine epidemic diarrhea virus (PEDV), which also has a sign...
CD11b maintains West Nile virus replication through modulation of immune response in human neuroblastoma cells
CD11b maintains West Nile virus replication through modulation of immune response in human neuroblastoma cells
West Nile virus (WNV) is a rapidly spreading mosquito-borne virus accounted for neuroinvasive diseases. An insight into WN...
CD11b maintains West Nile virus replication through modulation of immune response in human neuroblastoma cells
CD11b maintains West Nile virus replication through modulation of immune response in human neuroblastoma cells
West Nile virus (WNV) is a rapidly spreading mosquito-borne virus accounted for neuroinvasive diseases. An insight into WN...
Early administration of nirmatrelvir/ritonavir leads to faster negative SARS-CoV-2 nasal swabs than monoclonal antibodies in COVID 19 patients at high-risk for severe disease
Early administration of nirmatrelvir/ritonavir leads to faster negative SARS-CoV-2 nasal swabs than monoclonal antibodies in COVID 19 patients at high-risk for severe disease
Besides the well-established efficacy in preventing severe COVID-19, the impact of early treatments, namely antivirals and...
Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B
Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B
Hepatitis B virus (HBV) infection is a public health problem that seriously threatens human health. This study aimed to in...
Cross-neutralizing antibody against emerging Omicron subvariants of SARS-CoV-2 in infection-naïve individuals with homologous BNT162b2 or BNT162b2(WT + BA.4/5) bivalent booster vaccination
Cross-neutralizing antibody against emerging Omicron subvariants of SARS-CoV-2 in infection-naïve individuals with homologous BNT162b2 or BNT162b2(WT + BA.4/5) bivalent booster vaccination
Since the emergence of SARS-CoV-2, different variants and subvariants successively emerged to dominate global virus circul...
Epidemiology, clinical features and outcomes of hospitalized patients with COVID-19 by vaccination status: a multicenter historical cohort study
Epidemiology, clinical features and outcomes of hospitalized patients with COVID-19 by vaccination status: a multicenter historical cohort study
COVID-19 disease resulted in over six million deaths worldwide. Although vaccines against SARS-CoV-2 demonstrated efficacy...
Identification of the protein coding capability of coronavirus defective viral genomes by mass spectrometry
Identification of the protein coding capability of coronavirus defective viral genomes by mass spectrometry
During coronavirus infection, in addition to the well-known coronavirus genomes and subgenomic mRNAs, an abundance of defe...
HIV transmission and associated factors under the scale-up of HIV antiretroviral therapy: a population-based longitudinal molecular network study
HIV transmission and associated factors under the scale-up of HIV antiretroviral therapy: a population-based longitudinal molecular network study
To evaluate the prevention efficacy of scaling up HIV/AIDS antiretroviral therapy (ART) on HIV transmission at the populat...
Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
Human papillomaviruses (HPVs) induce a subset of head and neck squamous cell carcinomas (HNSCC) and anogenital cancers, pa...
Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis
Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis
Cervical cancer (CC) is one of the most common gynecologic tumors among women around the world. Although the etiological r...
Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses
Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share t...
Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.
Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.
We have recently identified a novel virus detected in alfalfa seed material. The virus was tentatively named alfalfa-assoc...
HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population
HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population
Human leucocyte antigen (HLA)-DR plays a crucial role in the immune response against hepatitis B virus (HBV). We aimed to ...
Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants
Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has challenged the effectiveness of...
Genome characteristics of atypical porcine pestivirus from abortion cases in Shandong Province, China
Genome characteristics of atypical porcine pestivirus from abortion cases in Shandong Province, China
Atypical porcine pestivirus (APPV) is a novel, highly variable porcine pestivirus. Previous reports have suggested that th...
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells
Promyelocytic leukemia protein (PML) is a primary component of PML nuclear bodies (PML-NBs). PML and PML-NBs play critical...
Screening for viral pathogens in the gastrointestinal tract from cases of sudden unexpected death in infancy at the Tygerberg Medico-legal Mortuary
Screening for viral pathogens in the gastrointestinal tract from cases of sudden unexpected death in infancy at the Tygerberg Medico-legal Mortuary
Sudden and unexpected death in infancy (SUDI) may be triggered by an external risk or exposure. Intestinal infections with...
HIV viral suppression at different thresholds and duration of treatment in the dolutegravir treatment era in Sierra Leone: a nationwide survey
HIV viral suppression at different thresholds and duration of treatment in the dolutegravir treatment era in Sierra Leone: a nationwide survey
Viral load assessment for people living with HIV is key for monitoring treatment and achieving the 95-95-95. In this study...
Phylogenomic assessment of 23 equid alphaherpesvirus 1 isolates obtained from USA-based equids
Phylogenomic assessment of 23 equid alphaherpesvirus 1 isolates obtained from USA-based equids
Equid alphaherpesvirus 1 (EHV-1) is a global viral pathogen of domestic equids which causes reproductive, respiratory and ...
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