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A mimic targets intracellular Staphylococcus aureus
In this study, Ge et al. develop a mimic of natural killer cells to target and eliminate intracellular Staphylococcus aureus.
Gut microbiota clocks in stress
Gut microbiota clocks in stress
In this study, Tofani et al. demonstrate that the gut microbiota regulates stress responsiveness in mice via the circadian...
Waning resistance
This study provides insights into how adaptive changes in evolved microbial communities can affect pathogen invasion.
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant infections, defined as the prolonged carriage of pathogenic bacteria even in the presence of antib...
Predicting phage–host specificity
In a recent study, Gaborieau, Vaysset, Tesson et al. developed a method to predict phage–host specificity using geno...
Designer viral receptors
In a recent study, Liu, Huang, Guo, McCallum et al. present a method to create functional, customized coronavirus receptor...
Iron gatekeeper in malaria
Loveridge and Sigala uncover a divalent metal transporter that is required for cellular iron metabolism in Plasmodium falc...
Hepatitis B and D virus entry
Hepatitis B and D virus entry
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of covalently closed circul...
Highly pathogenic H5N1 avian influenza virus outbreak in cattle: the knowns and unknowns
Competing interests Y.K. has received grant support from Daiichi Sankyo Ph...
Targeting the spread of antimicrobial resistance plasmids
Targeting the spread of antimicrobial resistance plasmids
A recent study demonstrates targeting plasmid-encoded bacterial proteins containing immunoglobulin-like domains to prevent...
Harnessing the plant microbiome for sustainable crop production
Harnessing the plant microbiome for sustainable crop production
Global research on the plant microbiome has enhanced our understanding of the complex interactions between plants and micr...
Tagging for degradation — bacteria do it too
In this Journal Club, Francesca Ester Morreale revisits a paper reporting that arginine phosphorylation marks proteins for...
Testing fast with uRAST
Testing fast with uRAST
In this study, Kim, Kang, Jang et al. report a phenotype-based, ultra-rapid and blood culture-free antimicrobial susceptib...
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide a...
Author Correction: Conservation and similarity of bacterial and eukaryotic innate immunity
In the version of the article initially published, in the “Effector-triggered immunity” section, the sentence now reading ...
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage is a major contributor to food waste and, hence, to the negative environmental sustainability impa...
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The skin barrier protects the human body from invasion by exogenous and pathogenic microorganisms. A breach in this barrie...
Microbial adaptability in changing environments
Microbial adaptability in changing environments
This Genome Watch article highlights the recent use of large-scale monitoring of natural microbiomes to examine feedback b...
COVID-19 drug discovery and treatment options
COVID-19 drug discovery and treatment options
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ha...
Shaking up that sick feeling with biofilm sugars
Shaking up that sick feeling with biofilm sugars
In this study, Granton et al. show that biofilm-associated exopolysaccharides produced by Pseudomonas aeruginosa control s...
Phages get snappy
Phages get snappy
This study shows that a single-stranded RNA phage binds to the Pseudomonas aeruginosa type IV pilus, leading to phage entr...
A never-ending defence fight
A never-ending defence fight
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, ...
Daughters remember to swarm
The data of the study suggest that bacteria possess a physiological iron memory that persists over multiple generations.
Staphylococcus aureus gets itchy
Staphylococcus aureus gets itchy
This study reports a mechanism whereby a Staphylococcus aureus protease induces itch by activating a host receptor on sens...
The honeybee microbiota and its impact on health and disease
The honeybee microbiota and its impact on health and disease
Honeybees (Apis mellifera) are key pollinators that support global agriculture and are long-established models for develop...
Jumping between hosts
In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sar...
Machine learning sheds light on microbial dark proteins
Machine learning sheds light on microbial dark proteins
This month’s Genome Watch highlights the recent use of machine learning to uncover functional ‘dark matterR...
Antibodies versus P. aeruginosa
In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing...
Keep calm with ammonia-producing microbiota
Keep calm with ammonia-producing microbiota
In this study, Wang et al. show that bacterium-derived intestinal ammonia modulates glutamine production in the mouse brai...
Urban malaria
This study provides evidence for a role of Anopheles stephensi in driving urban malaria outbreaks.
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