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A gut fungus protects the liver
A gut fungus protects the liver
This study reports that that a gut fungus produces a secondary metabolite that protects against metabolic disease in mice.
An engineered Vibrio to remediate ’em all
An engineered Vibrio to remediate ’em all
In this study, Su et al. engineered a Vibrio natriegens strain for the remediation of multiple organic pollutants.
Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses
Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses
Since their first detection in 1996, highly pathogenic avian influenza viruses with H5 haemagglutinin of the A/Goose/Guang...
Inheriting traits
This study explored the inheritance of bacterial metabolic activity at the single-cell level.
Metagenomics distilled: new k-mer-based methods
Metagenomics distilled: new k-mer-based methods
This Genome Watch highlights the advantages and limitations of k-mer approaches versus standard alignment-based methods fo...
Microbial interactions and ecology in fermented food ecosystems
Microbial interactions and ecology in fermented food ecosystems
Fermented foods and beverages, produced by the intentional growth of microorganisms, have long been among the most widely ...
Microorganisms thriving together as communities
Microorganisms thriving together as communities
This Genome Watch article discusses the dominance of uncultivated microorganisms in natural ecosystems and how the consequ...
Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility
Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility
Pseudomonas aeruginosa has long served as a model organism in microbiology, particularly for studies on gene expression, q...
A mimic targets intracellular Staphylococcus aureus
In this study, Ge et al. develop a mimic of natural killer cells to target and eliminate intracellular Staphylococcus aureus.
Gut microbiota clocks in stress
Gut microbiota clocks in stress
In this study, Tofani et al. demonstrate that the gut microbiota regulates stress responsiveness in mice via the circadian...
Waning resistance
This study provides insights into how adaptive changes in evolved microbial communities can affect pathogen invasion.
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant Salmonella during infection
Antibiotic-recalcitrant infections, defined as the prolonged carriage of pathogenic bacteria even in the presence of antib...
Predicting phage–host specificity
In a recent study, Gaborieau, Vaysset, Tesson et al. developed a method to predict phage–host specificity using geno...
Designer viral receptors
In a recent study, Liu, Huang, Guo, McCallum et al. present a method to create functional, customized coronavirus receptor...
Iron gatekeeper in malaria
Loveridge and Sigala uncover a divalent metal transporter that is required for cellular iron metabolism in Plasmodium falc...
Hepatitis B and D virus entry
Hepatitis B and D virus entry
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of covalently closed circul...
Targeting the spread of antimicrobial resistance plasmids
Targeting the spread of antimicrobial resistance plasmids
A recent study demonstrates targeting plasmid-encoded bacterial proteins containing immunoglobulin-like domains to prevent...
Harnessing the plant microbiome for sustainable crop production
Harnessing the plant microbiome for sustainable crop production
Global research on the plant microbiome has enhanced our understanding of the complex interactions between plants and micr...
Tagging for degradation — bacteria do it too
In this Journal Club, Francesca Ester Morreale revisits a paper reporting that arginine phosphorylation marks proteins for...
Testing fast with uRAST
Testing fast with uRAST
In this study, Kim, Kang, Jang et al. report a phenotype-based, ultra-rapid and blood culture-free antimicrobial susceptib...
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide a...
Author Correction: Conservation and similarity of bacterial and eukaryotic innate immunity
In the version of the article initially published, in the “Effector-triggered immunity” section, the sentence now reading ...
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage is a major contributor to food waste and, hence, to the negative environmental sustainability impa...
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The skin barrier protects the human body from invasion by exogenous and pathogenic microorganisms. A breach in this barrie...
Microbial adaptability in changing environments
Microbial adaptability in changing environments
This Genome Watch article highlights the recent use of large-scale monitoring of natural microbiomes to examine feedback b...
COVID-19 drug discovery and treatment options
COVID-19 drug discovery and treatment options
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ha...
Shaking up that sick feeling with biofilm sugars
Shaking up that sick feeling with biofilm sugars
In this study, Granton et al. show that biofilm-associated exopolysaccharides produced by Pseudomonas aeruginosa control s...
Phages get snappy
Phages get snappy
This study shows that a single-stranded RNA phage binds to the Pseudomonas aeruginosa type IV pilus, leading to phage entr...
A never-ending defence fight
A never-ending defence fight
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, ...