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Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Systemic fungal infections caused by Candida auris have been identified since 2009, with mortality rates and drug resistan...
Virulence Traits in Commensalism and Disease
Virulence Traits in Commensalism and Disease
Candida albicans is a common constituent of the normal human microbiota of the oro-gastrointestinal and vaginal tract. The...
Agent-Based Models of Virus Infection
Agent-Based Models of Virus Infection
Agent-based modelling (ABM) is a robust computational tool for investigating the dynamics of infectious disease spread and...
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Cholangiocarcinoma (CCA) is the most lethal and common malignant tumours that occur in the bile ducts. Although it is rela...
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
This review examines machine learning methods for host–pathogen protein–protein interaction (PPI) prediction. ...
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Increasing evidence shows that the onset of the host cytoskeleton changes during the viral infection process. The attainme...
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
It is now evident that the microorganisms living on and inside the human body modulate a myriad of host responses and acti...
Human Microbiome and Bacteriophages: Impacts on Health and Disease
Human Microbiome and Bacteriophages: Impacts on Health and Disease
This review explores the direct and indirect interactions between bacteriophages and the human microbiome, aiming to clari...
Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems
Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems
This review explores the application of classical ecological theory to host-associated microbiomes during initial coloniza...
Long-Read Sequencing for the Rapid Response to Infectious Diseases Outbreaks
Long-Read Sequencing for the Rapid Response to Infectious Diseases Outbreaks
Long-read sequencing (LRS) has revolutionized pathogen surveillance by enabling real-time, high-fidelity genomic analysis ...
MPOX: Resilient Strategies in Prevention and Diagnosis
MPOX: Resilient Strategies in Prevention and Diagnosis
MPOX, a zoonotic orthopoxvirus, has resurged in recent years, culminating in extensive outbreaks in 2022 and 2024. The evo...
Models for Studying Fungal Pathogenesis
Models for Studying Fungal Pathogenesis
Fungal pathogens represent a serious cause of disease and death in immunodeficient and immunocompromised patients. The inc...
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Bacterial infections and antibiotic resistance contribute to global mortality. Despite many infections being preventable a...
Candida albicans Virulence Traits in Commensalism and Disease
Candida albicans Virulence Traits in Commensalism and Disease
Candida albicans is a common constituent of the normal human microbiota of the oro-gastrointestinal and vaginal tract. The...
Molecular Insights Into the Interplay Between Host Platelets and Fungal Pathogens
Molecular Insights Into the Interplay Between Host Platelets and Fungal Pathogens
Despite the rise in invasive fungal infections, little is understood about these illnesses, especially the relationship be...
Molecular Mechanisms of KSHV Latency Establishment and Maintenance
Molecular Mechanisms of KSHV Latency Establishment and Maintenance
This review summarizes results from recent studies that shed light on viral and cellular mechanisms that contribute to lat...
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Despite host antiviral responses and antiretroviral therapy, HIV-1 continues to persist in myeloid cell reservoirs. Hence,...
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 undergoes genetic mutations like many other viruses. Some mutations lead to the emergence of new Variants of Co...
Foodborne Helminthiasis
Foodborne Helminthiasis
This review focuses on key foodborne helminths: providing an overview of their lifecycles and major transmission routes to...
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
As the first identified human oncogenic virus, Epstein-Barr virus (EBV) is widely circulating in humans. EBV presents main...
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
The Wnt signaling pathway is one of the key pathways involved in hematopoietic progenitor cell (HPC) proliferation and dif...
Candida auris Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Candida auris Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Systemic fungal infections caused by Candida auris have been identified since 2009, with mortality rates and drug resistan...
Gut Microbiota and Autoimmune Diseases: Mechanisms, Treatment, Challenges, and Future Recommendations
Gut Microbiota and Autoimmune Diseases: Mechanisms, Treatment, Challenges, and Future Recommendations
This review provides an overview of the role of dysbiosis (imbalanced gut microbiota) in the maintenance of host homeostas...
Bringing Balance: Immune Interactions Regulating Murine Gammaherpesvirus 68 Latency
Bringing Balance: Immune Interactions Regulating Murine Gammaherpesvirus 68 Latency
Gammaherpesviruses constitute the chief virus family that is capable of exhibiting true latency. Latency allows the viral ...
The Impact of Climate Change on Human Fungal Pathogen Distribution and Disease Incidence
The Impact of Climate Change on Human Fungal Pathogen Distribution and Disease Incidence
This review aims to compile the current knowledge on the impact of climate change on human pathogenic fungi. Ongoing surve...
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
This review comprehensively examines host-vaginal microbiota interactions, the composition of the vaginal microbiota, and ...
Fish Acanthocephalans as Potential Human Pathogens
Fish Acanthocephalans as Potential Human Pathogens
Acanthocephalans attach to the gastro-intestinal mucosa of the host (mammals, birds, reptiles, amphibians, fish) by use of...
Post-COVID Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia in the Pediatric Population
Post-COVID Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia in the Pediatric Population
Long COVID, or post-COVID Condition, is increasingly recognized in children and adolescents, despite being less studied co...
Nutritional Immunity and Fungal Pathogens: A New Role for Manganese
Nutritional Immunity and Fungal Pathogens: A New Role for Manganese
Copper, zinc, iron, and manganese are essential micronutrients for all living organisms. Microbial pathogens must acquire ...
Exploring the Potential Role of the Genus Kudoa (Myxosporea: Kudoidae) as an Emerging Seafood-Borne Parasite in Humans
Exploring the Potential Role of the Genus Kudoa (Myxosporea: Kudoidae) as an Emerging Seafood-Borne Parasite in Humans
This article reviews and summarises the recent findings on emerging seafood-borne parasites, Kudoa spp., that have receive...
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