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Implementation of Alert System for Early Diagnosis of Acute Kidney Injury: Paving the Way for National Public Health Advisory in India
Implementation of Alert System for Early Diagnosis of Acute Kidney Injury: Paving the Way for National Public Health Advisory in India
This study is the first attempt to create and implement an alert system to facilitate early diagnosis and timely intervent...
Continuous Quality Enhancement in Clinical Diagnostic Laboratories Through Lean and Six Sigma Methodologies: A Narrative Review
Continuous Quality Enhancement in Clinical Diagnostic Laboratories Through Lean and Six Sigma Methodologies: A Narrative Review
Since long laboratories have been burdened heavily with the pressure of producing correct and timely reports. For the bene...
Comparison of HDL Cholesterol Efflux Capacity Assays and the Effect of Assay Selection on CEC and Coronary Heart Disease
Comparison of HDL Cholesterol Efflux Capacity Assays and the Effect of Assay Selection on CEC and Coronary Heart Disease
Recent epidemiological studies have highlighted the inverse relationship between high-density lipoprotein cholesterol (HDL...
Synergistic Effects of Platinum-Based Drugs and Curcumin on Liposomal Delivery in HSC-3 Oral Cancer Cells
Synergistic Effects of Platinum-Based Drugs and Curcumin on Liposomal Delivery in HSC-3 Oral Cancer Cells
This study delves into the potentiation of cytotoxic effects through the strategic incorporation of curcumin within two di...
The Necessity of Age Stratified Validation of Martin Hopkins Formula: Observations from a Meta-Analysis
The Necessity of Age Stratified Validation of Martin Hopkins Formula: Observations from a Meta-Analysis
Martin Hopkins formula proposed in 2013 uses a varying factor based on the triglyceride and non-HDL cholesterol values, in...
Utility and Sensitivity of Gene Polymorphism in Early Prediction and Association with Risk of Metabolic Primary Antiphospholipid Syndrome: Cohort Study
Utility and Sensitivity of Gene Polymorphism in Early Prediction and Association with Risk of Metabolic Primary Antiphospholipid Syndrome: Cohort Study
Toll-like Receptor 10 (TLR10) represents the sole member of the human toll-like receptor family that inhibits the innate i...
Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review
Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review
Cancer remains one of the most pressing global health concerns, ranking as the second leading cause of death worldwide. Ox...
Exploring the Therapeutic Potential of Esculetin in Mitigating Cyclophosphamide-Induced Hepato-Toxicity
Exploring the Therapeutic Potential of Esculetin in Mitigating Cyclophosphamide-Induced Hepato-Toxicity
Cyclophosphamide, an extensively utilized alkylating agent in oncological therapies, is correlated with considerable hepat...
Role of Vitamin-E as a Vital Nutrient in Health and Diseases
Role of Vitamin-E as a Vital Nutrient in Health and Diseases
Vitamin E, known for its antioxidant properties, has been studied extensively for its potential health benefits, particula...
Identification of Genes and Pathways Involved in Breast Cancer Subtypes through Expression Meta-analysis
Identification of Genes and Pathways Involved in Breast Cancer Subtypes through Expression Meta-analysis
Early diagnosis of breast cancer (BC), that whether it is invasive or non-invasive, is crucial in the field of breast surg...
Do the Early Pregnancy Serum Levels of VEGF & PlGF Predict the Onset of Preeclampsia: An Experience from a Tertiary Center
Do the Early Pregnancy Serum Levels of VEGF & PlGF Predict the Onset of Preeclampsia: An Experience from a Tertiary Center
This study was conducted to evaluate the utility of serum vascular endothelial growth factor (VEGF) and placental growth f...
The Implication of ENSA, K-ATP Channel Encoding Gene Variations in Type 1 Diabetes in Children of South Indian Population
The Implication of ENSA, K-ATP Channel Encoding Gene Variations in Type 1 Diabetes in Children of South Indian Population
A polygenic condition called type 1 diabetes mellitus (T1D), causes hyperglycemia inferable from insulin deficiency, invol...
Capsicum in Clinical Biochemistry: Insights into its Role in Health and Disease
Capsicum in Clinical Biochemistry: Insights into its Role in Health and Disease
Members of the Solanaceae family, also known as peppers, widely celebrate the culinary and medicinal significance of Capsi...
hsa-miR-3529-5p through F2RL3 Regulation as an Enhancer of Sensitivity to Cisplatin
hsa-miR-3529-5p through F2RL3 Regulation as an Enhancer of Sensitivity to Cisplatin
The emergence of drug resistance in gastric cancer presents a critical challenge in oncological treatments, often leading ...
Optimization of Automated Dimethylmethylene Blue Assay for Quantification of Pediatric Urine Samples
Optimization of Automated Dimethylmethylene Blue Assay for Quantification of Pediatric Urine Samples
The metachromatic dye dimethylmethylene blue is used to quantify total glycosaminoglycans in urine. Understanding the inte...
Anti-tumor Effects of Polyphenols via Targeting Cancer Driving Signaling Pathways: A Review
Anti-tumor Effects of Polyphenols via Targeting Cancer Driving Signaling Pathways: A Review
The use of drugs in chemotherapy poses numerous side effects. Hence the use of natural substances that can help in the pre...
Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer
Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer
Breast cancer is the leading cause of cancer-related mortality among women worldwide. MicroRNAs (miRNAs), short non-coding...
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
Medulloblastoma (MB), a malignant tumour arising in the brain, exhibits distinct microRNA expression patterns. One such mi...
Assessment of Oxidative Stress Levels in Women with Different Phenotypes of Polycystic Ovary Syndrome and its Correlation with Lipid and Hormonal Profile
Assessment of Oxidative Stress Levels in Women with Different Phenotypes of Polycystic Ovary Syndrome and its Correlation with Lipid and Hormonal Profile
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder and one of the leading causes of infertility in women....
Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy
Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy
Colon rectal cancer still stands as the third most common form of cancer worldwide. 90% of colorectal cancer failure is at...
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is associated with low-grade systemic inflammation and an increase in inflammation mark...
The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality
The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality
Heart failure (HF) is a life-threatening syndrome with high prevalence and mortality rates. Soluble urokinase plasminogen ...
Vitamin D in Disease Prevention and Cure-Part I: An Update on Molecular Mechanism and Significance on Human Health
Vitamin D in Disease Prevention and Cure-Part I: An Update on Molecular Mechanism and Significance on Human Health
Vitamin D, a versatile secosteroid hormone, continues to captivate scientific interest due to its multifaceted influence o...
Likelihood of a Novel Pathogenic LDLR Mutant Allele Inherited Preferentially within an Indian Family with Familial Hypercholesterolemia
Likelihood of a Novel Pathogenic LDLR Mutant Allele Inherited Preferentially within an Indian Family with Familial Hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated levels of low-density lipop...
Genetic Variants of AGO1*rs595961 and AGO2*rs4961280 with Susceptibility to Bladder Carcinoma
Genetic Variants of AGO1*rs595961 and AGO2*rs4961280 with Susceptibility to Bladder Carcinoma
The microRNA (miRNA) biogenesis mechanism remains elusive, yet various genetic variants may play a role in predicting the ...
Evaluation of Proflo-U® Platform: A Novel Fluorescence-Based Point of Care Device for Quantitative Estimation of Urine Albumin
Evaluation of Proflo-U® Platform: A Novel Fluorescence-Based Point of Care Device for Quantitative Estimation of Urine Albumin
Urine albumin estimation has a very high diagnostic significance. The scope of this assay widens if the method has potenti...
Exploring the Diagnostic Utility of Serum Cofilin-1 and 2 Levels in Patients with Acute Coronary Syndrome: A Case–Control Pilot Study
Exploring the Diagnostic Utility of Serum Cofilin-1 and 2 Levels in Patients with Acute Coronary Syndrome: A Case–Control Pilot Study
Acute coronary syndrome (ACS) is caused by decreased blood flow to the heart muscle after plaque rupture and thrombus form...
Lack of Glutamate Synthase in Streptococcus zooepidemicus makes a Natural Driving Force for Increasing Hyaluronic Acid Production
Lack of Glutamate Synthase in Streptococcus zooepidemicus makes a Natural Driving Force for Increasing Hyaluronic Acid Production
Hyaluronic acid (HA) has many applications in the pharmaceutical and cosmetic industries. Streptococcus zooepidemicus is n...
Assessing Colorectal Cancer Susceptibility in Kashmir, India: Insights from Xenobiotic Metabolism Gene Variants and Family Cancer History—A Comprehensive Case–Control Study
Assessing Colorectal Cancer Susceptibility in Kashmir, India: Insights from Xenobiotic Metabolism Gene Variants and Family Cancer History—A Comprehensive Case–Control Study
A family history of cancer(FHC) is a known risk factor for CRC with both genetic and other factors. A case–control s...
Point-of-Care Capillary Compared to Venous Bilirubin Measurement in Neonates
Point-of-Care Capillary Compared to Venous Bilirubin Measurement in Neonates
We aimed to evaluate the agreement between the point-of-care (POC) capillary bilirubin measurement with POC venous samples...
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