Adams GR, Hather BM, Baldwin KM, Dudley GA (1993) Skeletal muscle myosin heavy chain composition and resistance training. J Appl Physiol 74:911–915. https://doi.org/10.1152/jappl.1993.74.2.911

Article  PubMed  Google Scholar 

Artigas-Arias M, Curi R, Marzuca-Nassr GN (2024a) Myogenic microRNAs as therapeutic targets for skeletal muscle mass wasting in breast cancer models. Int J Mol Sci 25:6714. https://doi.org/10.3390/ijms25126714

Article  PubMed  PubMed Central  Google Scholar 

Artigas-Arias M, Alegría-Molina A, Vidal-Seguel N, Muñoz-Cofre R, Carranza-Leiva J, Sepúlveda-Lara A et al (2024b) Skeletal muscle mass, strength, and physical performance gains are similar between healthy postmenopausal women and postmenopausal breast cancer survivors after 12 weeks of resistance exercise training. Support Care Cancer 32:818. https://doi.org/10.1007/s00520-024-08973-7

Article  PubMed  PubMed Central  Google Scholar 

Avis NE, Deimling GT (2008) Cancer survivorship and aging. Cancer 113:3519–3529. https://doi.org/10.1002/cncr.23941

Article  PubMed  Google Scholar 

Barrett-O’Keefe Z, Helgerud J, Wagner PD, Richardson RS (2012) Maximal strength training and increased work efficiency: contribution from the trained muscle bed. J Appl Physiol 113:1846–1851. https://doi.org/10.1152/japplphysiol.00761.2012

Article  PubMed  PubMed Central  Google Scholar 

Beaudry RI, Kirkham AA, Thompson RB, Grenier JG, Mackey JR, Haykowsky MJ (2020) Exercise intolerance in anthracycline-treated breast cancer survivors: the role of skeletal muscle bioenergetics, oxygenation, and composition. Oncologist 25:e852–e860. https://doi.org/10.1634/theoncologist.2019-0777

Article  PubMed  PubMed Central  Google Scholar 

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74:229–263. https://doi.org/10.3322/caac.21834

Article  PubMed  Google Scholar 

Broskey NT, Boss A, Fares E-J, Greggio C, Gremion G, Schlüter L et al (2015) Exercise efficiency relates with mitochondrial content and function in older adults. Physiol Rep 3:e12418. https://doi.org/10.14814/phy2.12418

Article  PubMed  PubMed Central  Google Scholar 

But-Hadzic J, Dervisevic M, Karpljuk D, Videmsek M, Dervisevic E, Paravlic A et al (2021) Six-minute walk distance in breast cancer survivors—a systematic review with meta-analysis. Int J Environ Res Public Health 18:2591. https://doi.org/10.3390/ijerph18052591

Article  PubMed  PubMed Central  Google Scholar 

Castaneda C, Layne JE, Munoz-Orians L, Gordon PL, Walsmith J, Foldvari M et al (2002) A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes Care 25:2335–2341. https://doi.org/10.2337/diacare.25.12.2335

Article  PubMed  Google Scholar 

Committee ATS, on Proficiency Standards for Clinical Pulmonary Function Laboratories, (2002) ATS Statement. Am J Respir Crit Care Med 166(1):111–117. https://doi.org/10.1164/ajrccm.166.1.at1102

Article  Google Scholar 

Conley KE, Jubrias SA, Esselman PC (2000) Oxidative capacity and ageing in human muscle. J Physiol 526:203–210. https://doi.org/10.1111/j.1469-7793.2000.t01-1-00203.x

Article  PubMed  PubMed Central  Google Scholar 

Consitt LA, Dudley C, Saxena G (2019) Impact of endurance and resistance training on skeletal muscle glucose metabolism in older adults. Nutrients 11:2636. https://doi.org/10.3390/nu11112636

Article  PubMed  PubMed Central  Google Scholar 

Enright PL, McBurnie MA, Bittner V, Tracy RP, McNamara R, Arnold A et al (2003) The 6-min Walk Test*. Chest 123:387–398. https://doi.org/10.1378/chest.123.2.387

Article  PubMed  Google Scholar 

Ficarra S, Thomas E, Bianco A, Gentile A, Thaller P, Grassadonio F et al (2022) Impact of exercise interventions on physical fitness in breast cancer patients and survivors: a systematic review. Breast Cancer 29:402–418. https://doi.org/10.1007/s12282-022-01347-z

Article  PubMed  Google Scholar 

Foulkes SJ, Haykowsky MJ, Li T, Wang J, Kennedy M, Kirkham AA et al (2024a) Determinants of impaired peak oxygen uptake in breast cancer survivors: JACC: cardioOncology primer. JACC: Cardiooncology 6:33–37. https://doi.org/10.1016/j.jaccao.2023.11.005

Article  PubMed  Google Scholar 

Foulkes S, Haykowsky MJ, Howden EJ, Antill Y, Nightingale S, Daly RM et al (2024b) Physiological determinants underlying a meaningful improvement in VO2peak following exercise training in anthracycline-treated breast cancer survivors. Eur J Prev Cardiol. https://doi.org/10.1093/eurjpc/zwae175.021

Article  PubMed  Google Scholar 

Galiano-Castillo N, Arroyo-Morales M, Ariza-Garcia A, Sánchez-Salado C, Fernández-Lao C, Cantarero-Villanueva I et al (2016) The six-minute walk test as a measure of health in breast cancer patients. J Aging Phys Act 24:508–515. https://doi.org/10.1123/japa.2015-0056

Article  PubMed  Google Scholar 

Groennebaek T, Vissing K (2017) Impact of resistance training on skeletal muscle mitochondrial biogenesis, content, and function. Front Physiol. https://doi.org/10.3389/fphys.2017.00713

Article  PubMed  PubMed Central  Google Scholar 

Guigni BA, Callahan DM, Tourville TW, Miller MS, Fiske B, Voigt T et al (2018) Skeletal muscle atrophy and dysfunction in breast cancer patients: role for chemotherapy-derived oxidant stress. Am J Physiol Cell Physiol 315:C744–C756. https://doi.org/10.1152/ajpcell.00002.2018

Article  PubMed  PubMed Central  Google Scholar 

Haykowsky MJ, Kirkham AA, Li T, Pituskin E, Thompson RB, Paterson DI et al (2022) Determinants of oxygen utilization in breast cancer: similarities between heart failure with preserved ejection fraction. Prog Cardiovasc Dis 74:45–52. https://doi.org/10.1016/j.pcad.2022.10.005

Article  PubMed  Google Scholar 

Hill AV (1922) The maximum work and mechanical efficiency of human muscles, and their most economical speed. J Physiol 56:19–41. https://doi.org/10.1113/jphysiol.1922.sp001989

Article  PubMed  PubMed Central  Google Scholar 

Hill K, Jenkins SC, Cecins N, Philippe DL, Hillman DR, Eastwood PR (2008) Estimating maximum work rate during incremental cycle ergometry testing from six-minute walk distance in patients with chronic obstructive pulmonary disease. Arch Phys Med Rehabil 89:1782–1787. https://doi.org/10.1016/j.apmr.2008.01.020

Article  PubMed  Google Scholar 

Hoff J, Helgerud J, Wisløff U (1999) Maximal strength training improves work economy in trained female cross-country skiers. Med Sci Sports Exerc 31:870–877. https://doi.org/10.1097/00005768-199906000-00016

Article  PubMed  Google Scholar 

Hunter GR, Newcomer BR, Weinsier RL, Karapondo DL, Larson-Meyer DE, Joanisse DR et al (2002) Age is independently related to muscle metabolic capacity in premenopausal women. J Appl Physiol 93:70–76. https://doi.org/10.1152/japplphysiol.01239.2001

Article  PubMed  Google Scholar 

Hurria A, Jones L, Muss HB (2016) Cancer treatment as an accelerated aging process: assessment, biomarkers, and interventions. Amer Soci Clin Oncol Educat Book. https://doi.org/10.1200/EDBK_156160

Article  Google Scholar 

Keating NL, Nørredam M, Landrum MB, Huskamp HA, Meara E (2005) Physical and mental health status of older long-term cancer survivors. J Am Geriatr Soc 53:2145–2152. https://doi.org/10.1111/j.1532-5415.2005.00507.x

Article  PubMed  Google Scholar 

Kirkham AA, Haykowsky MJ, Beaudry RI, Grenier JG, Mackey JR, Pituskin E et al (2021) Cardiac and skeletal muscle predictors of impaired cardiorespiratory fitness post-anthracycline chemotherapy for breast cancer. Sci Rep 11:14005. https://doi.org/10.1038/s41598-021-93241-5

Article  PubMed  PubMed Central  Google Scholar 

Kubo Y, Naito T, Mori K, Osawa G, Aruga E (2017) Skeletal muscle loss and prognosis of breast cancer patients. Support Care Cancer 25:2221–2227. https://doi.org/10.1007/s00520-017-3628-5

Article  PubMed  Google Scholar 

Layec G, Hart CR, Trinity JD, Le Fur Y, Jeong E-K, Richardson RS (2015) Skeletal muscle work efficiency with age: the role of non-contractile processes. Clin Sci 128:213–223. https://doi.org/10.1042/CS20140274

Article