Novel miRNAs, miR-937-3p, miR-4536-3p, and miR-4650-5p, can Modulate Neuronal Differentiation via the Wnt/MAPK Pathway in SH-SY5Y Cells

Diener C, Keller A, Meese E (2022) Emerging concepts of miRNA therapeutics: from cells to clinic. Trends Genet 38(6):613–626

Article  CAS  PubMed  Google Scholar 

Ho PT, Clark IM, Le LT (2022) MicroRNA-Based Diagnosis and Therapy. Int J Mol Sci 23(13):7167

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kataria P, Surela N, Chaudhary A, Das J (2022) MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection. Int J Environ Res Public Health 19(4):2395

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang S, Talukder A, Cha M, Li X, Hu H (2021) Computational annotation of miRNA transcription start sites. Brief Bioinform 22(1):380–392

Article  PubMed  Google Scholar 

Chen L, Heikkinen L, Wang C, Yang Y, Sun H, Wong G (2019) Trends in the development of miRNA bioinformatics tools. Brief Bioinform 20(5):1836–1852

Article  CAS  PubMed  PubMed Central  Google Scholar 

Correia de Sousa M, Gjorgjieva M, Dolicka D, Sobolewski C, Foti M (2019) Deciphering miRNAs’ Action through miRNA Editing. Int J Mol Sci 20(24):6249

Article  PubMed  PubMed Central  Google Scholar 

Kang MJ, Park SY, Han JS (2019) MicroRNA-24-3p regulates neuronal differentiation by controlling hippocalcin expression. Cell Mol Life Sci 76(22):4569–4580

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kilikevicius A, Meister G, Corey DR (2022) Reexamining assumptions about miRNA-guided gene silencing. Nucleic Acids Res 50(2):617–634

Article  CAS  PubMed  Google Scholar 

Valihrach L, Androvic P, Kubista M (2020) Circulating miRNA analysis for cancer diagnostics and therapy. Mol Aspects Med 72:100825

Article  CAS  PubMed  Google Scholar 

Yang B, Liu Y, Li L, Deng H, Xian L (2020) MicroRNA-200a promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through extensive target genes. Mol Med Rep 21(5):2073–2084

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dobrzycka M, Sulewska A, Biecek P, Charkiewicz R, Karabowicz P, Charkiewicz A, Golaszewska K, Milewska P et al (2023) miRNA Studies in Glaucoma: A Comprehensive Review of Current Knowledge and Future Perspectives. Int J Mol Sci 24(19):14699

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li D, Zhang J, Li J (2020) Role of miRNA sponges in hepatocellular carcinoma. Clin Chim Acta 500:10–19

Article  CAS  PubMed  Google Scholar 

Xu Y, Guo B, Liu X, Tao K (2021) miR-34a inhibits melanoma growth by targeting ZEB1. Aging 13(11):15538–15547

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sanuki R, Yamamura T (2021) Tumor Suppressive Effects of miR-124 and Its Function in Neuronal Development. Int J Mol Sci 22(11):5919

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan C, Li Y, Lan T, Wang W, Long Y, Yu SY (2022) Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression. Mol Ther 30(3):1300–1314

Article  CAS  PubMed  Google Scholar 

Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horre K et al (2021) Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease. Cell Stem Cell 28(10):1805–1821

Article  CAS  PubMed  Google Scholar 

Esteves M, Serra-Almeida C, Saraiva C, Bernardino L (2020) New insights into the regulatory roles of microRNAs in adult neurogenesis. Curr Opin Pharmacol 50(38):45

Google Scholar 

Pan WL, Chopp M, Fan B, Zhang R, Wang X, Hu J, Zhang XM, Zhang ZG et al (2019) Ablation of the microRNA-17-92 cluster in neural stem cells diminishes adult hippocampal neurogenesis and cognitive function. FASEB J 33(4):5257–5267

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen LJ, Hu BB, Shi XL, Ren MM, Yu WB, Cen SD, Hu RD, Deng H (2017) Baicalein enhances the osteogenic differentiation of human periodontal ligament cells by activating the Wnt/beta-catenin signaling pathway. Arch Oral Biol 78:100–108

Article  CAS  PubMed  Google Scholar 

Haradahira T, Schwendner SW, Kojima M, Counsell RE (1989) Potential tumor- or organ-imaging agents 29 Radioiodinated esters and amides of 20-hydroxy- and 20-aminopregn-5-en-3 beta-ols. J Med Chem 32(3):609–12

Article  CAS  PubMed  Google Scholar 

Serafino A, Giovannini D, Rossi S, Cozzolino M (2020) Targeting the Wnt/beta-catenin pathway in neurodegenerative diseases: recent approaches and current challenges. Expert Opin Drug Discov 15(7):803–822

Article  CAS  PubMed  Google Scholar 

Zhao M, Tang Y, Zhou Y, Zhang J (2019) Deciphering Role of Wnt Signalling in Cardiac Mesoderm and Cardiomyocyte Differentiation from Human iPSCs: Four-dimensional control of Wnt pathway for hiPSC-CMs differentiation. Sci Rep 9(1):19389

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bengoa-Vergniory N, Kypta RM (2015) Canonical and noncanonical Wnt signaling in neural stem/progenitor cells. Cell Mol Life Sci 72(21):4157–4172

Article  CAS  PubMed  PubMed Central  Google Scholar 

Inestrosa NC, Varela-Nallar L (2015) Wnt signalling in neuronal differentiation and development. Cell Tissue Res 359(1):215–223

Article  CAS  PubMed  Google Scholar 

Oliva CA, Montecinos-Oliva C, Inestrosa NC (2018) Wnt Signaling in the Central Nervous System: New Insights in Health and Disease. Prog Mol Biol Transl Sci 153:81–130

Article  CAS  PubMed  Google Scholar 

Li X, Ortiz MA, Kotula L (2020) The physiological role of Wnt pathway in normal development and cancer. Exp Biol Med 245(5):411–426

Article  CAS  Google Scholar 

Zhang Q, Pan Y, Ji J, Xu Y, Zhang Q, Qin L (2021) Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review. Cell Death Discov 7(1):287

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arredondo SB, Guerrero FG, Herrera-Soto A, Jensen-Flores J, Bustamante DB, Oñate-Ponce A, Henny P, Varas-Godoy M et al (2020) Wnt5a promotes differentiation and development of adult-born neurons in the hippocampus by noncanonical Wnt signaling. Stem Cells 38(3):422–436

Article  CAS  PubMed  Google Scholar 

Jang S, Park JS, Jeong HS (2015) Neural Differentiation of Human Adipose Tissue-Derived Stem Cells Involves Activation of the Wnt5a/JNK Signalling. Stem Cells Int 2015:178618

Article  PubMed  PubMed Central  Google Scholar 

Choi J, Gang S, Ramalingam M, Hwang J, Jeong H, Yoo J, Cho HH, Kim BC et al (2024) BML-281 promotes neuronal differentiation by modulating Wnt/Ca(2+) and Wnt/PCP signaling pathway. Mol Cell Biochem 479(9):2391–2403

Article  CAS  PubMed 

Comments (0)

No login
gif