Tsimpiris A, Tsolianos I, Grigoriadis A, et al. Association of chronic periodontitis with multiple sclerosis: a systematic review and meta-analysis. Multiple Scler Relat Disord. 2023;77: 104874.

Google Scholar 

Stringer G. Chronic periodontitis, dantamoolaroga, indicates chronic systemic inflammation and reduces longevity. J Ayurv Integr Med. 2024;15: 101048.

CAS  Google Scholar 

Cardoso EM, Reis C, Manzanares-Céspedes MC. Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases. Postgrad Med. 2018;130:98–104.

PubMed  Google Scholar 

Sayad A, Mirzajani S, Gholami L, et al. Emerging role of long non-coding RNAs in the pathogenesis of periodontitis. Biomed Pharmacother Biomedecine pharmacotherapie. 2020;129:110362.

CAS  PubMed  Google Scholar 

Suzuki S, Yamada S. Epigenetics in susceptibility, progression, and diagnosis of periodontitis. Jpn Dental Sci Rev. 2022;58:183–92.

Google Scholar 

Zhu ZX, Liu Y, Wang J, et al. A novel lncRNA-mediated epigenetic regulatory mechanism in periodontitis. Int J Biol Sci. 2023;19:5187–203.

CAS  PubMed  PubMed Central  Google Scholar 

Bao H, Jiang Y, Wang N, Su H, Han X. Long noncoding RNAs MALAT1 and HOTTIP act as serum biomarkers for hepatocellular carcinoma. Cancer Control J Moffitt Cancer Center. 2024;31:10732748241284820.

Google Scholar 

Basavarajappa DS, Padam KSR, Chakrabarty S, An NK, Radhakrishnan R. The regulatory role of HOX interacting lncRNA in oral cancer—an in silico analysis. J Oral Pathol Med. 2022;51:684–93.

CAS  PubMed  Google Scholar 

Lian Y, Cai Z, Gong H, et al. HOTTIP: a critical oncogenic long non-coding RNA in human cancers. Mol BioSyst. 2016;12:3247–53.

CAS  PubMed  Google Scholar 

Zhang C, Hu Z, Fu Y, Wang J. Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-506 pathway. Aging. 2024;16:10832–40.

CAS  PubMed  PubMed Central  Google Scholar 

Shao P, Liu H, Xue Y, Xiang T, Sun Z. LncRNA HOTTIP promotes inflammatory response in acute gouty arthritis via miR-101-3p/BRD4 axis. Int J Rheum Dis. 2023;26:305–15.

CAS  PubMed  Google Scholar 

Wang G, Xu YL, Zhang XH, Tang L, Li Y. LncRNA HOTTIP regulates TLR4 promoter methylation by recruiting H3K4 methyltransferase MLL1 to affect apoptosis and inflammatory response of fibroblast-like synoviocyte in rheumatoid arthritis. Kaohsiung J Med Sci. 2024;40:335–47.

CAS  PubMed  Google Scholar 

Lee YH, Yu CC, Hsieh PL, et al. Inhibition of lncRNA HOTTIP ameliorated myofibroblast activities and inflammatory cytokines in oral submucous fibrosis. J Formosan Med Assoc Taiwan yi zhi. 2021;120:1188–93.

CAS  PubMed  Google Scholar 

Zhang J, Zhu H, Li L, et al. New mechanism of LncRNA: In addition to act as a ceRNA. Non-coding RNA Res. 2024;9:1050–60.

CAS  Google Scholar 

Zhao X, Li S, Wang Z, Bai N, Feng Y. miR‑101‑3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF‑κB pathway. Mol Med Rep. 2021;23:359.

Google Scholar 

Wang H, Guo Y, Mi N, Zhou L. miR-101-3p and miR-199b-5p promote cell apoptosis in oral cancer by targeting BICC1. Mol Cell Probes. 2020;52: 101567.

CAS  PubMed  Google Scholar 

Vohra F, Bukhari IA, Sheikh SA, et al. Effectiveness of scaling and root planing with and without adjunct probiotic therapy in the treatment of chronic periodontitis among shamma users and non-users: a randomized controlled trial. J Periodontol. 2020;91:1177–85.

CAS  PubMed  Google Scholar 

Chatzopoulos GS, Jiang Z, Marka N, Wolff LF. Association between periodontitis extent, severity, and progression rate with systemic diseases and smoking: a retrospective study. J Pers Med. 2023;13:814.

PubMed  PubMed Central  Google Scholar 

Heidari Z, Moudi B, Mahmoudzadeh-Sagheb H. Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview. BMC Oral Health. 2019;19:29.

PubMed  PubMed Central  Google Scholar 

Mattick JS, Amaral PP, Carninci P, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol. 2023;24:430–47.

CAS  PubMed  PubMed Central  Google Scholar 

Zhang L, Lv H, Cui Y, Shi R. The role of long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) in chronic periodontitis progression. Bioengineered. 2022;13:2336–45.

CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Zhu J, Wang WH, et al. Exosomal lncRNA HCP5 derived from human bone marrow mesenchymal stem cells improves chronic periodontitis by miR-24-3p/HO1/P38/ELK1 pathway. Heliyon. 2024;10: e34203.

CAS  PubMed  PubMed Central  Google Scholar 

Yu M, Chi C. lncRNA FGD5-AS1 and miR-130a can be used for prognosis analysis of patients with chronic periodontitis. Biomed Res Int. 2021;2021:8544914.

PubMed  PubMed Central  Google Scholar 

Chen Q, Cao M, Ge H. Knockdown of MALAT1 inhibits the progression of chronic periodontitis via targeting miR-769-5p/HIF3A axis. Biomed Res Int. 2021;2021:8899863.

PubMed  PubMed Central  Google Scholar 

Wu S, Li Z, Wang J, Liu L, Pang Y. Correlation analysis of miR-1246 expression in saliva of patients with chronic periodontitis and periodontal indexes, inflammatory cytokines, and protease molecules. Evidence-based Complement Altern Med eCAM. 2022;2022:1949159.

Google Scholar 

Lu T, Zhu J, Yang S, Shen Z, Zhong L. Effects of Foxp3 gene silencing on the expression of inflammatory cytokines and the proliferation and migration of human periodontal ligament fibroblasts in an inflammatory environment. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China J Stomatol. 2023;41:269–75.

Google Scholar 

Karagkouni D, Karavangeli A, Paraskevopoulou MD, Hatzigeorgiou AG. Characterizing miRNA-lncRNA Interplay. Methods Mol Biol (Clifton, NJ). 2021;2372:243–62.

CAS  Google Scholar