Assessment of the Capability of Mesenchymal Stem Cells and/or Pyrroloquinoline Quinone in Compensating the Age-Related Dysfunctions of AMP-Activated Protein Kinase Pathway in Wistar Rats

Li, Z., Zhang, Z., Ren, Y., Wang, Y., Fang, J., Yue, H., Ma, S., & Guan, F. (2021). Aging and age‐related diseases: From mechanisms to therapeutic strategies. Biogerontology, 22(2), 165–187. https://doi.org/10.1007/s10522-021-09910-5.

Article  PubMed  PubMed Central  Google Scholar 

Li, Y., Tian, X., Luo, J., Bao, T., Wang, S., & Wu, X. (2024). Molecular mechanisms of aging and anti-aging strategies. Cell Communication and Signaling, 22(1), 285 https://doi.org/10.1186/s12964-024-01663-1.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gregg, E. W., Chen, H., Wagenknecht, L. E., Clark, J. M., Delahanty, L. M., Bantle, J., Pownall, H. J., Johnson, K. C., Safford, M. M., Kitabchi, A. E., Pi-Sunyer, F. X., Wing, R. R., Bertoni, A. G., & Look AHEAD Research Group. (2012). Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA, 308(23), 2489 https://doi.org/10.1001/jama.2012.67929. for the.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Asejeje, F. O., & Ogunro, O. B. (2024). Deciphering the mechanisms, biochemistry, physiology, and social habits in the process of aging. Archives of Gerontology and Geriatrics Plus, 1(1), 100003 https://doi.org/10.1016/j.aggp.2023.100003.

Article  Google Scholar 

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194–1217. https://doi.org/10.1016/j.cell.2013.05.039.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Rowe, J. W., & Kahn, R. L. (2015). Successful aging 2.0: Conceptual expansions for the 21st century. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 70(4), 593–596. https://doi.org/10.1093/geronb/gbv025.

Article  PubMed  Google Scholar 

Guo, J., Huang, X., Dou, L., Yan, M., Shen, T., Tang, W., & Li, J. (2022). Aging and aging-related diseases: From molecular mechanisms to interventions and treatments. Signal Transduction and Targeted Therapy, 7(1), 391 https://doi.org/10.1038/s41392-022-01251-0.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Umbayev, B., Askarova, S., Almabayeva, A., Saliev, T., Masoud, A.-R., & Bulanin, D. (2020). Galactose-induced skin aging: The role of oxidative stress. Oxidative Medicine and Cellular Longevity, 2020, 1–15. https://doi.org/10.1155/2020/7145656.

Article  CAS  Google Scholar 

Wang, S., Zhang, X., Ke, Z., Wen, X., Li, W., Liu, W., Zhuang, X.-D., & Liao, L. (2022). D‐galactose‐induced cardiac ageing: A review of model establishment and potential interventions. Journal of Cellular and Molecular Medicine, 26(21), 5335–5359. https://doi.org/10.1111/jcmm.17580.

Article  PubMed  PubMed Central  Google Scholar 

Azman, K. F., Safdar, A., & Zakaria, R. (2021). D-galactose-induced liver aging model: Its underlying mechanisms and potential therapeutic interventions. Experimental Gerontology, 150, 111372 https://doi.org/10.1016/j.exger.2021.111372.

Article  PubMed  CAS  Google Scholar 

Maldonado, E., Morales-Pison, S., Urbina, F., & Solari, A. (2023). Aging hallmarks and the role of oxidative stress. Antioxidants, 12(3), 651 https://doi.org/10.3390/antiox12030651.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yu, M., Zhang, H., Wang, B., Zhang, Y., Zheng, X., Shao, B., Zhuge, Q., & Jin, K. (2021). Key signaling pathways in aging and potential interventions for healthy aging. Cells, 10(3), 660 https://doi.org/10.3390/cells10030660.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cencioni, C., Spallotta, F., Martelli, F., Valente, S., Mai, A., Zeiher, A., & Gaetano, C. (2013). Oxidative stress and epigenetic regulation in ageing and age-related diseases. International Journal of Molecular Sciences, 14(9), 17643–17663. https://doi.org/10.3390/ijms140917643.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chen, Y., Hu, Y., Zhou, X., Zhao, Z., Yu, Q., Chen, Z., Wang, Y., Xu, P., Yu, Z., Guo, C., Zhang, X., & Shi, Y. (2022). Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing γδ T cells. Cell and Tissue Research, 388(3), 549–563. https://doi.org/10.1007/s00441-022-03616-x.

Article  PubMed  CAS  Google Scholar 

Grune, T., Jung, T., Merker, K., & Davies, K. J. A. (2004). Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and ‘aggresomes’ during oxidative stress, aging, and disease. The International Journal of Biochemistry & Cell Biology, 36(12), 2519–2530. https://doi.org/10.1016/j.biocel.2004.04.020.

Article  CAS  Google Scholar 

Schmucker, D. L. (2005). Age-related changes in liver structure and function: Implications for disease? Experimental Gerontology, 40(8–9), 650–659. https://doi.org/10.1016/j.exger.2005.06.009.

Article  PubMed  CAS  Google Scholar 

Radonjić, T., Dukić, M., Jovanović, I., Zdravković, M., Mandić, O., Popadić, V., Nikolić, N., Klašnja, S., Divac, A., Todorović, Z., & Branković, M. (2022). Aging of liver in its different diseases. International Journal of Molecular Sciences, 23(21), 13085 https://doi.org/10.3390/ijms232113085.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Jiang, M., Zheng, Z., Wang, X., Chen, Y., Qu, J., Ding, Q., Zhang, W., Liu, Y.-S., Yang, J., Tang, W., Hou, Y., He, J., Wang, L., Huang, P., Li, L.-C., He, Z., Gao, Q., Lu, Q., Wei, L., & Wang, Y. (2024). A biomarker framework for liver aging: The Aging Biomarker Consortium consensus statement. Life Medicine, 3(1), lnae004 https://doi.org/10.1093/lifemedi/lnae004.

Article  PubMed  PubMed Central  Google Scholar 

Stahl, E. C., Haschak, M. J., Popovic, B., & Brown, B. N. (2018). Macrophages in the aging liver and age-related liver disease. Frontiers in Immunology, 9, 2795 https://doi.org/10.3389/fimmu.2018.02795.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Nivukoski, U., Niemelä, M., Bloigu, A., Bloigu, R., Aalto, M., Laatikainen, T., & Niemelä, O. (2020). Combined effects of lifestyle risk factors on fatty liver index. BMC Gastroenterology, 20(1), 109 https://doi.org/10.1186/s12876-020-01270-7.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ling, Z., Zhang, C., He, J., Ouyang, F., Qiu, D., Li, L., Li, Y., Li, X., Duan, Y., Luo, D., Xiao, S., & Shen, M. (2023). Association of healthy lifestyles with non-alcoholic fatty liver disease: A prospective Cohort Study in chinese government employees. Nutrients, 15(3), 604 https://doi.org/10.3390/nu15030604.

Article  PubMed  PubMed Central  Google Scholar 

Shackelford, D. B., & Shaw, R. J. (2009). The LKB1–AMPK pathway: Metabolism and growth control in tumour suppression. Nature Reviews Cancer, 9(8), 563–575. https://doi.org/10.1038/nrc2676.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Giardiello, F. M., Brensinger, J. D., Tersmette, A. C., Goodman, S. N., Petersen, G. M., Booker, S. V., Cruz-Correa, M., & Offerhaus, J. A. (2000). Very high risk of cancer in familial Peutz–Jeghers syndrome. Gastroenterology, 119(6), 1447–1453. https://doi.org/10.1053/gast.2000.20228.

Article  PubMed  CAS  Google Scholar 

Ylikorkala, A., Rossi, D. J., Korsisaari, N., Luukko, K., Alitalo, K., Henkemeyer, M., & Mäkelä, T. P. (2001). Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science, 293(5533), 1323–1326. https://doi.org/10.1126/science.1062074.

Article  PubMed  CAS  Google Scholar 

Mihaylova, M. M., & Shaw, R. J. (2011). The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nature Cell Biology, 13(9), 1016–1023. https://doi.org/10.1038/ncb2329.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Keipert, S., Ost, M., Johann, K., Imber, F., Jastroch, M., van Schothorst, E. M., Keijer, J., & Klaus, S. (2014). Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine. American Journal of Physiology-Endocrinology and Metabolism, 306(5), E469–E482. https://doi.org/10.1152/ajpendo.00330.2013.

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