Effect of subanesthetic dose of esketamine on early postoperative depression in elderly patients with Sarcopenia

Yuan S, Larsson SC. Epidemiology of Sarcopenia: prevalence, risk factors, and consequences. Metabolism. 2023;144:155533.

Article  CAS  PubMed  Google Scholar 

Sanad HT, Hamza SA, Metwaly RG, Elbehery HM. Sarcopenia and related functional outcomes following hip surgery among Egyptian geriatric patients with hip fracture. Cureus. 2023;15(8):e43166.

PubMed  PubMed Central  Google Scholar 

Williams GR, Dunne RF, Giri S, Shachar SS, Caan BJ. Sarcopenia in the older adult with Cancer. J Clin Oncol. 2021;39(19):2068–78.

Article  PubMed  PubMed Central  Google Scholar 

Li Z, Tong X, Ma Y, Bao T, Yue J. Prevalence of depression in patients with Sarcopenia and correlation between the two diseases: systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2022;13(1):128–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhong Q, Jiang L, An K, Zhang L, Li S, An Z. Depression and risk of Sarcopenia: a national cohort and mendelian randomization study. Front Psychiatry. 2023;14:1263553.

Article  PubMed  PubMed Central  Google Scholar 

Stubbs B, Aluko Y, Myint PK, Smith TO. Prevalence of depressive symptoms and anxiety in osteoarthritis: a systematic review and meta-analysis. Age Ageing. 2016;45(2):228–35.

Article  PubMed  Google Scholar 

Guo J, Qiu D, Gu HW, et al. Efficacy and safety of perioperative application of ketamine on postoperative depression: a meta-analysis of randomized controlled studies. Mol Psychiatry. 2023;28(6):2266–76.

CAS  PubMed  PubMed Central  Google Scholar 

Mashour GA, Ben Abdallah A, Pryor KO, et al. Intraoperative ketamine for prevention of depressive symptoms after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial. Br J Anaesth. 2018;121(5):1075–83.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xia CY, Guo YX, Lian WW, et al. The NLRP3 inflammasome in depression: potential mechanisms and therapies. Pharmacol Res. 2023;187:106625.

Article  CAS  PubMed  Google Scholar 

Jiang J, Shi Y, Cao J, Lu Y, Sun G, Yang J. Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation. Lipids Health Dis. 2021;20(1):19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lyu D, Wang F, Zhang M, et al. Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway. Psychopharmacology. 2022;239(10):3201–12.

Article  CAS  PubMed  Google Scholar 

Moaddel R, Zanos P, Farmer CA, et al. Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration. Transl Psychiatry. 2022;12(1):179.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Subramanian S, Haroutounian S, Palanca BJA, Lenze EJ. Ketamine as a therapeutic agent for depression and pain: mechanisms and evidence. J Neurol Sci. 2022;434:120152.

Article  CAS  PubMed  Google Scholar 

Jawad MY, Di Vincenzo JD, Badulescu S, et al. The therapeutic role of ketamine and esketamine in treating psychopathological domains of depression. Neuropharmacology. 2023;223:109299.

Article  CAS  PubMed  Google Scholar 

Popova V, Daly EJ, Trivedi M, et al. Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression: a Randomized double-blind active-controlled study. Am J Psychiatry. 2019;176(6):428–38.

Article  PubMed  Google Scholar 

Dwyer JB, Landeros-Weisenberger A, Johnson JA, et al. Efficacy of intravenous ketamine in adolescent treatment-resistant depression: a randomized midazolam-controlled trial. Am J Psychiatry. 2021;178(4):352–62.

Article  PubMed  Google Scholar 

Chen Y, Guo Y, Wu H, et al. Perioperative Adjunctive Esketamine for Postpartum Depression among women undergoing Elective Cesarean Delivery: a Randomized Clinical Trial. JAMA Netw Open. 2024;7(3):e240953.

Article  PubMed  PubMed Central  Google Scholar 

Nemec U, Heidinger B, Sokas C, Chu L, Eisenberg RL. Diagnosing Sarcopenia on thoracic computed tomography: quantitative Assessment of skeletal muscle Mass in patients undergoing transcatheter aortic valve replacement. Acad Radiol. 2017;24(9):1154–61.

Article  PubMed  Google Scholar 

Lučiūnaitė A, McManus RM, Jankunec M, et al. Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia. J Neurochem. 2020;155(6):650–61.

Article  PubMed  Google Scholar 

Liu P, Li P, Li Q, et al. Effect of pretreatment of S-Ketamine on postoperative depression for breast Cancer patients. J Invest Surg. 2021;34(8):883–8.

Article  PubMed  Google Scholar 

Li S, Zhuo Z, Li R, Guo K. Efficacy of esketamine for the treatment of postpartum depression and pain control following cesarean section: a randomized, double-blind, controlled clinical trial. BMC Anesthesiol. 2024;24(1):52.

Article  PubMed  PubMed Central  Google Scholar 

Min M, Du C, Chen X, Xin W. Effect of subanesthetic dose of esketamine on postoperative rehabilitation in elderly patients undergoing hip arthroplasty. J Orthop Surg Res. 2023;18(1):268.

Article  PubMed  PubMed Central  Google Scholar 

Zhang Z, Zhang WH, Lu YX et al. Intraoperative Low-Dose S-Ketamine Reduces Depressive Symptoms in Patients with Crohn’s Disease Undergoing Bowel Resection: A Randomized Controlled Trial. J Clin Med. 2023;12(3).

Vu T, Smith JA. The pathophysiology and management of depression in cardiac surgery patients. Front Psychiatry. 2023;14:1195028.

Article  PubMed  PubMed Central  Google Scholar 

Wang H, He Y, Sun Z, et al. Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression. J Neuroinflammation. 2022;19(1):132.

Article  PubMed  PubMed Central  Google Scholar 

Li Y, Song W, Tong Y, et al. Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis. J Neuroinflammation. 2021;18(1):1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu F, Han L, Wang Y, et al. Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors. BMC Med. 2023;21(1):7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vandanmagsar B, Youm YH, Ravussin A, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17(2):179–88.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang M, Li Q, Mao M, et al. Evaluation of clinical effects of esketamine on depression in patients with missed miscarriage: a randomized, controlled, double-blind trial. J Affect Disord. 2023;329:525–30.

Article  CAS  PubMed  Google Scholar 

Lepping P, Whittington R, Sambhi RS, et al. Clinical relevance of findings in trials of CBT for depression. Eur Psychiatry. 2017;45:207–11.

Article  CAS  PubMed  Google Scholar 

Ma F, Cao G, Lu L, Zhu Y, Li W, Chen L. Electroacupuncture versus Escitalopram for mild to moderate Post-stroke Depression: a randomized non-inferiority trial. Front Psychiatry. 2024;15:1332107.

Article  PubMed  PubMed Central  Google Scholar 

Luo T, Deng Z, Ren Q, Mu F, Zhang Y, Wang H. Effects of esketamine on postoperative negative emotions and early cognitive disorders in patients undergoing non-cardiac thoracic surgery: a randomized controlled trial. J Clin Anesth. 2024;95:111447.

Comments (0)

No login
gif