The therapeutic effects of various tonic traditional Chinese medicines on demyelinating diseases

Aquilina J, Neves JB, Tran MG (2020) An overview of study designs. Br J Hosp Med (Lond) 81:1–6

Article  PubMed  Google Scholar 

Awad A, Trenfield SJ, Pollard TD, Ong JJ, Elbadawi M, McCoubrey LE, Goyanes A, Gaisford S, Basit AW (2021) Connected healthcare: improving patient care using digital health technologies. Adv Drug Deliv Rev 178:113958

Article  PubMed  CAS  Google Scholar 

Bagaev A, Kotlov N, Nomie K, Svekolkin V, Gafurov A, Isaeva O, Osokin N, Kozlov I, Frenkel F, Gancharova O, Almog N, Tsiper M, Ataullakhanov R, Fowler N (2021) Conserved pan-cancer microenvironment subtypes predict response to immunotherapy. Cancer Cell 39(6):845-865.e7

Article  PubMed  CAS  Google Scholar 

Batiha GE, Beshbishy AM, Ikram M, Mulla ZS, El-Hack MEA, Taha AE, Algammal AM, Elewa YHA (2020) The pharmacological activity, biochemical properties, and pharmacokinetics of the major natural polyphenolic flavonoid: quercetin. Foods. https://doi.org/10.3390/foods9030374

Article  PubMed  PubMed Central  Google Scholar 

Bhujbal SV, Mitra B, Jain U, Gong Y, Agrawal A, Karki S, Taylor LS, Kumar S, Zhou Q. Tony (2021) Pharmaceutical amorphous solid dispersion: a review of manufacturing strategies. Acta Pharm Sin B 11:2505–2536

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bogie JF, Stinissen P, Hellings N, Hendriks JJ (2011) Myelin-phagocytosing macrophages modulate autoreactive T cell proliferation. J Neuroinflammation 8:85

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bolleddula J, Brady K, Bruin G, Lee A, Martin JA, Walles M, Xu K, Yang TY, Zhu X, Yu H (2022) Absorption, distribution, metabolism, and excretion of therapeutic proteins: current industry practices and future perspectives. Drug Metab Dispos 50:837–845

Article  PubMed  CAS  Google Scholar 

Briel M, Müller KF, Meerpohl JJ, von Elm E, Lang B, Motschall E, Gloy V, Lamontagne F, Schwarzer G, Bassler D (2013) Publication bias in animal research: a systematic review protocol. Syst Rev 2:23

Article  PubMed  PubMed Central  Google Scholar 

Brown BL, Mitra-Majumdar M, Joyce K, Ross M, Pham C, Darrow JJ, Avorn J, Kesselheim AS (2022) Trends in the quality of evidence supporting FDA drug approvals: results from a literature review. J Health Polit Policy Law 47:649–672

Article  PubMed  Google Scholar 

Brown K, Theofanous D, Britton RG, Aburido G, Pepper C, Sri Undru S, Howells L (2024) Resveratrol for the management of human health: how far have we come? A systematic review of resveratrol clinical trials to highlight gaps and opportunities. Int J Mol Sci. 25(2):747. https://doi.org/10.3390/ijms25020747

Article  PubMed  PubMed Central  Google Scholar 

Chapman KL, Holzgrefe H, Black LE, Brown M, Chellman G, Copeman C, Couch J, Creton S, Gehen S, Hoberman A, Kinter LB, Madden S, Mattis C, Stemple HA, Wilson S (2013) Pharmaceutical toxicology: designing studies to reduce animal use, while maximizing human translation. Regul Toxicol Pharmacol 66:88–103

Article  PubMed  CAS  Google Scholar 

Chen KJ (2021) Chinese expert consensus on clinical application of oral Ginkgo biloba preparations (2020). Chin J Integr Med 27:163–169

Article  PubMed  Google Scholar 

Chen XJ, Zhang XJ, Shui YM, Wan JB, Gao JL (2016) Anticancer activities of protopanaxadiol- and protopanaxatriol-type ginsenosides and their metabolites. Evid Based Complement Alternat Med 2016:5738694

Article  PubMed  PubMed Central  Google Scholar 

Chen MH, Goverover Y, Genova HM, DeLuca J (2020) Cognitive efficacy of pharmacologic treatments in multiple sclerosis: a systematic review. CNS Drugs 34:599–628

Article  PubMed  PubMed Central  Google Scholar 

Chen L, Qin Z, Ruan ZB (2023) Hyperoside alleviates doxorubicin-induced myocardial cells apoptosis by inhibiting the apoptosis signal-regulating kinase 1/p38 pathway. PeerJ 11:e15315

Article  PubMed  PubMed Central  Google Scholar 

Chen S, Pei H, Geng J, Zong Y, Zhao Y, Li J, He Z, Du R (2025) Effects of polypeptides derived from Velvet antler on D-gal induced brain aging model. Int J Biol Macromol 320:145659

Article  PubMed  CAS  Google Scholar 

Compston A, Scolding N, Wren D, Noble M (1991) The pathogenesis of demyelinating disease: insights from cell biology. Trends Neurosci 14:175–182

Article  PubMed  CAS  Google Scholar 

de Sá Coutinho D, Pacheco MT, Frozza RL, Bernardi A (2018) Anti-inflammatory effects of resveratrol: mechanistic insights. Int J Mol Sci 19(6):1812. https://doi.org/10.3390/ijms19061812

Article  CAS  Google Scholar 

Ding X, Ma X, Meng P, Yue J, Li L, Xu L (2024) Potential effects of traditional Chinese medicine in anti-aging and aging-related diseases: current evidence and perspectives. Clin Interv Aging 19:681–693

Article  PubMed  PubMed Central  Google Scholar 

Dong C (2021) Cytokine regulation and function in T cells. Annu Rev Immunol 39:51–76

Article  PubMed  CAS  Google Scholar 

Dubey RK, Kumar B (2025) A comprehensive overview of traditional Chinese medicine (TCM). Zhongguo Ying Yong Sheng Li Xue Za Zhi 41:e20250015

PubMed  Google Scholar 

Ebnet K, Vestweber D (1999) Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines. Histochem Cell Biol 112:1–23

Article  PubMed  CAS  Google Scholar 

’EGb (2003) 761: Ginkgo Biloba extract, ginkor’. Drugs R D 4:188–193

Google Scholar 

Fang H, Hou YR, Huang HY, Wu DW, Jia SP, Tang Y, Li N (2024) [International comparison and assessment of the quality of drug clinical trial implementation in China based on scientific regulatory system]. Zhonghua Zhong Liu Za Zhi 46:987–993

PubMed  CAS  Google Scholar 

Fantacuzzi M, Amoroso R, Carradori S, De Filippis B (2022) Resveratrol-based compounds and neurodegeneration: recent insight in multitarget therapy. Eur J Med Chem 233:114242

Article  PubMed  CAS  Google Scholar 

Feng Z, Sun Q, Chen W, Bai Y, Hu D, Xie X (2019) The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review. Mol Med 25:57

Article  PubMed  PubMed Central  CAS  Google Scholar 

Foulkes R, Man E, Thind J, Yeung S, Joy A, Hoskins C (2020) The regulation of nanomaterials and nanomedicines for clinical application: current and future perspectives. Biomater Sci 8:4653–4664

Article  PubMed  CAS  Google Scholar 

Franssen H (2019) Physiology of myelinated nerve conduction and pathophysiology of demyelination. Adv Exp Med Biol 1190:85–106

Article  PubMed  CAS  Google Scholar 

Franssen H, Straver DC (2014) Pathophysiology of immune-mediated demyelinating neuropathies–Part II: neurology. Muscle Nerve 49:4–20

Article  PubMed  CAS  Google Scholar 

Frau J, Coghe G, Lorefice L, Fenu G, Cocco E (2023) The role of microorganisms in the etiopathogenesis of demyelinating diseases. Life (Basel) 13(6):1309

PubMed  CAS  Google Scholar 

Gao C, Jiang J, Tan Y, Chen S (2023) Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal Transduct Target Ther 8:359

Article  PubMed  PubMed Central  Google Scholar 

Ge H, Si L, Li C, Huang J, Sun L, Wu L, Xie Y, Xiao L, Wang G (2025) The Antidepressant Effect of Resveratrol Is Related to Neuroplasticity Mediated by the ELAVL4-Bdnf mRNA Pathway. Int J Mol Sci 26(3):1113. https://doi.org/10.3390/ijms26031113

Article  PubMed 

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