Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, Wang Y-T, Salter MW, Tymianski M (2002) Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions. Science 298(5594):846–850. https://doi.org/10.1126/science.1072873

Article  CAS  PubMed  Google Scholar 

Ables JL, DeCarolis NA, Johnson MA, Rivera PD, Gao Z, Cooper DC, Radtke F, Hsieh J, Eisch AJ (2010) Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. J Neurosci 30(31):10484–10492. https://doi.org/10.1523/JNEUROSCI.4721-09.2010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL et al (2023) Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer’s disease. Alzheimer’s & Dementia 19(6):2585–2594. https://doi.org/10.1002/alz.12906

Article  CAS  Google Scholar 

Ahlfeld J, Filser S, Schmidt F, Wefers AK, Merk DJ, Glas R, Herms J, Schuller U (2017) Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex. Sci Rep 7(1):6137. https://doi.org/10.1038/s41598-017-06150-x

Article  CAS  PubMed Central  Google Scholar 

Baker SA, Baker KA, Hagg T (2004) Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone. Eur J Neurosci 20(2):575–579. https://doi.org/10.1111/j.1460-9568.2004.03486.x

Article  PubMed  Google Scholar 

Bauersachs HG, Bengtson CP, Weiss U, Hellwig A, García-Vilela C, Zaremba B, Kaessmann H, Pruunsild P, Bading H (2022) N-methyl-d-aspartate receptor-mediated preconditioning mitigates excitotoxicity in human induced pluripotent stem cell-derived brain organoids. Neuroscience 484:83–97. https://doi.org/10.1016/j.neuroscience.2021.12.026

Article  CAS  PubMed  Google Scholar 

Beckervordersandforth R, Ebert B, Schäffner I, Moss J, Fiebig C, Shin J, Moore DL, Ghosh L, Trinchero MF, Stockburger C et al (2017) Role of mitochondrial metabolism in the control of early lineage progression and aging phenotypes in adult hippocampal neurogenesis. Neuron 93(3):560–573. https://doi.org/10.1016/j.neuron.2016.12.017

Article  CAS  PubMed  Google Scholar 

Belozor OS, Shuvaev AN, Fritsler YV, Shuvaev AN (2022) NMDA receptor antagonists as potential therapy in cerebellar degenerative disorders. Annals Clin Exp Neurol 16(2):58–69. https://doi.org/10.54101/ACEN.2022.2.7

Bhatnagar A et al (2023) Novel EAAT2 activators improve motor and cognitive impairment in a transgenic model of Huntington’s disease. Front Behav Neurosci 17:1176777. https://doi.org/10.3389/fnbeh.2023.1176777

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF (2018) Triheteromeric GluN1/GluN2A/GluN2C NMDARs with unique single-channel properties are the dominant receptor population in cerebellar granule cells. Neuron 99(2):315–328. https://doi.org/10.1016/j.neuron.2018.06.010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boutin C, Hardt O, Chevigny A, Core N, Goebbels S, Seidenfaden R, Bosio A, Cremer H (2010) NeuroD1 induces terminal neuronal differentiation in olfactory neurogenesis. Proc Natl Acad Sci 107(3):1201–1206. https://doi.org/10.1073/pnas.0909015107

Article  PubMed  Google Scholar 

Brorson JR, Manzolillo PA, Miller RJ (1994) Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells. J Neurosci 14(1):187–197. https://doi.org/10.1523/JNEUROSCI.14-01-00187.1994

Article  CAS  PubMed  Google Scholar 

Celio M (1990) Calbindin D-28k and parvalbumin in the rat nervous system. Neuroscience 35(2):375–475. https://doi.org/10.1016/0306-4522(90)90091-H

Article  CAS  PubMed  Google Scholar 

Chen H-L, Pistollato F, Hoeppner DJ, Ni H-T, McKay RD, Panchision DM (2007) Oxygen tension regulates survival and fate of mouse central nervous system precursors at multiple levels. Stem Cells 25(9):2291–2301. https://doi.org/10.1634/stemcells.2006-0609

Article  PubMed  Google Scholar 

Chen Q, Yamada T, Miyagawa K, Murata A, Shoji M, Nakatani K (2024) A new small molecule DoNA binding to CAG repeat RNA. Bioorganic Medicinal Chem 98:117580. https://doi.org/10.1016/j.bmc.2023.117580

Choi DW (1987) Ionic dependence of glutamate neurotoxicity. J Neurosci 7(2):369–379. https://doi.org/10.1523/JNEUROSCI.07-02-00369.1987

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi DW, Koh J-Y, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci 8(1):185–196. https://doi.org/10.1523/JNEUROSCI.08-01-00185.1988

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chuang C-S, Chang J-C, Soong B-W, Chuang S-F, Lin T-T, Cheng W-L, Orr HT, Liu C-S (2019) Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1. Kaohsiung J Med Sci 35(11):679–685. https://doi.org/10.1002/kjm2.12106

Article  CAS  PubMed  PubMed Central  Google Scholar 

Coles-Takabe BL, Brain I, Purpura KA, Karpowicz P, Zandstra PW, Morshead CM, Van der Kooy D (2008) Don’t look: growing clonal versus nonclonal neural stem cell colonies. Stem Cells 26(11):2938–2944. https://doi.org/10.1634/stemcells.2008-0558

Article  PubMed  Google Scholar 

Cooper F, Souilhol C, Haston S, Gray S, Boswell K, Gogolou A, Frith TJ, Stavish D, James BM, Bose D etal (2024) Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors. Development 151(3). https://doi.org/10.1242/dev.202098

Cougnoux A, Yerger JC, Fellmeth M, Serra-Vinardell J, Navid F, Wassif CA, Cawley NX, Porter FD (2021) Reduction of glutamate neurotoxicity: a novel therapeutic approach for Niemann-Pick disease, type C1. Mol Genet Metab 134(4):330–336. https://doi.org/10.1016/j.ymgme.2021.11.008

Article  CAS  PubMed  PubMed Central  Google Scholar 

Couillard-Despres S, Winner B, Schaubeck S, Aigner R, Vroemen M, Weidner N, Bogdahn U, Winkler J, Kuhn H-G, Aigner L (2005) Doublecortin expression levels in adult brain reflect neurogenesis. Eur J Neurosci 21(1):1–14. https://doi.org/10.1111/j.1460-9568.2004.03813.x

Article  PubMed  Google Scholar 

Cvetanovic M, Hu Y-S, Opal P (2017) Mutant ataxin-1 inhibits neural progenitor cell proliferation in SCA1. The Cerebellum 16:340–347. https://doi.org/10.1007/s12311-016-0794-9

Article  CAS  PubMed  Google Scholar 

Ding J, Shao Y, Zhou H-H, Ma Q-R, Zhang Y-W, Ding Y-X, He Y-Q, Liu J (2018) Effect of NMDA on proliferation and apoptosis in hippocampal neural stem cells treated with MK-801. Exp Ther Med 16(2):1137–1142. https://doi.org/10.3892/etm.2018.6346

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dmitriev RI, Zhdanov AV, Nolan YM, Papkovsky DB (2013) Imaging of neurosphere oxygenation with phosphorescent probes. Biomaterials 34(37):9307–9317. https://doi.org/10.1016/j.biomaterials.2013.08.065

Article  CAS  PubMed  Google Scholar 

Doetsch F, Caille I, Lim DA, García-Verdugo JM, Alvarez-Buylla A (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97(6):703–716. https://doi.org/10.1016/S0092-8674(00)80783-7

Article  CAS  PubMed  Google Scholar 

Drydale E, Rath P, Holden K, Holt G, Havins L, Johnson T, Bancroft J, Handunnetthi L (2024) Stem-cell derived neurosphere assay highlights the effects of viral infection on human cortical development. Brain Behav Immun 115:718–726. https://doi.org/10.21203/rs.3.rs-2184467/v1

Edamakanti CR, Do J, Didonna A, Martina M, Opal P et al (2018) Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1. J Clin Investig 128(6):2252–2265. https://doi.org/10.1172/JCI96765

Article  PubMed  PubMed Central  Google Scholar 

Edamakanti CR, Mohan V, Opal P (2023) Reactive Bergmann glia play a central role in spinocerebellar ataxia inflammation via the JNK pathway. J Neuroinflammation 20(1):126. https://doi.org/10.1186/s12974-023-02801-1

Article  PubMed  PubMed Central  Google Scholar 

Esclapez M, Tillakaratne N, Kaufman DL, Tobin AJ, Houser CR (1994) Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms. J Neurosci 14(3):1834–1855. https://doi.org/10.1523/JNEUROSCI.14-03-01834.1994

Article