Greb, J.E., A.M. Goldminz, J.T. Elder, M.G. Lebwohl, D.D. Gladman, J.J. Wu, N.N, et al. 2016. Psoriasis. Nature Reviews. Disease Primers 2: 16082

Boehncke, W.H., and M.P. Schön. 2015. Psoriasis. Lancet (London, England) 386: 983–994.

Article  CAS  PubMed  Google Scholar 

Song, J.K., Y. Zhang, X.Y. Fei, Y.R. Chen, Y. Luo, J.S. Jiang, et al. 2022. Classification and biomarker gene selection of pyroptosis-related gene expression in psoriasis using a random forest algorithm. Frontiers in Genetics 13: 850108.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deng, G., Y. Zhang, J. Song, Y. Zhang, Q. Zheng, Y. Luo, et al. 2024. The role and therapeutic strategies for tissue-resident memory T cells, central memory T cells, and effector memory T cells in psoriasis. Immunology 173: 470–480.

Article  CAS  PubMed  Google Scholar 

Hong, S.R., S.J. Lee, J.W. Shim, Y.S. Choi, Y.M. Lee, K.W. Song, et al. 2001. Study on gelatin-containing artificial skin IV: A comparative study on the effect of antibiotic and EGF on cell proliferation during epidermal healing. Biomaterials 22: 2777–2783.

Article  CAS  PubMed  Google Scholar 

Dai, H., Y. Zhou, C. Tong, Y. Guo, F. Shi, Y. Wang, and P. Shen. 2018. Restoration of CD3+CD56+ cell level improves skin lesions in severe psoriasis: A pilot clinical study of adoptive immunotherapy for patients with psoriasis using autologous cytokine-induced killer cells. Cytotherapy 20: 1155–1163.

Article  CAS  PubMed  Google Scholar 

Lee, M.R., and A.J. Cooper. 2006. Immunopathogenesis of psoriasis. The Australasian Journal of Dermatology 47: 151–159.

Article  PubMed  Google Scholar 

Pérez-Lorenzo, R., L. Núñez-Oreza, P. Garma-Quen, E. López-Pacheco, and G. Bricaire-Bricaire. 2006. Peripheral blood mononuclear cells proliferation and Th1/Th2 cytokine production in response to streptococcal M protein in psoriatic patients. International journal of dermatology 45: 1365–4632.

Article  Google Scholar 

Lin, Hsi-Hsien., Martin Stacey, Joan Stein-Streilein, and Siamon Gordon. 2010. F4/80: The macrophage-specific adhesion-GPCR and its role in immunoregulation. Advances in Experimental Medicine and Biology 706: 149–156.

Article  CAS  PubMed  Google Scholar 

Sun, Y., J. Zhang, R. Huo, T. Zhai, H. Li, P. Wu, et al. 2015. Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation. International Immunopharmacology 24: 392–399.

Article  CAS  PubMed  Google Scholar 

Chan, K.S., S. Sano, K. Kiguchi, J. Anders, N. Komazawa, J. Takeda, and J. DiGiovanni. 2004. Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis. The Journal of clinical investigation 114: 720–728.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sano, S., K.S. Chan, S. Carbajal, J. Clifford, M. Peavey, K. Kiguchi, et al. 2005. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nature Medicine 11: 43–49.

Article  CAS  PubMed  Google Scholar 

Zhou, M., H. Xu, D. Zhang, C. Si, X. Zhou, H. Zhao, et al. 2021. Decreased PIBF1/IL6/p-STAT3 during the mid-secretory phase inhibits human endometrial stromal cell proliferation and decidualization. Journal of Advanced Research 30: 15–25.

Article  CAS  PubMed  Google Scholar 

Brandt, D., M. Sergon, S. Abraham, K. Mäbert, and C.M. Hedrich. 2017. TCR+CD3+CD4-CD8- effector T cells in psoriasis. Clinical Immunology (Orlando, Fla.) 181: 51–59.

Koreck, A., A. Surányi, B.J. Szöny, A. Farkas, Z. Bata-Csörgö, L. Kemény, and A. Dobozy. 2002. CD3+CD56+ NK T cells are significantly decreased in the peripheral blood of patients with psoriasis. Clinical and Experimental Immunology 127: 176–182.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Niu, J., Z. Zhai, F. Hao, Y. Zhang, Z. Song, and H. Zhong. 2018. Dissection of a circulating CD3+ CD20+ T cell subpopulation in patients with psoriasis. Clinical and Experimental Immunology 192: 206–212.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ishida, Y., Y. Agata, K. Shibahara, and T. Honjo. 1992. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. The EMBO journal 11: 3887–3895.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Voudouri, D., V. Nikolaou, K. Laschos, A. Charpidou, N. Soupos, L. Triantafyllopoulou, et al. 2017. Anti-PD1/PDL1 induced psoriasis. Current Problems in Cancer 41: 407–412.

Article  PubMed  Google Scholar 

Kim, D.S., J.H. Je, S.H. Kim, D. Shin, T.G. Kim, D.Y. Kim, et al. 2015. Programmed death-ligand 1, 2 expressions are decreased in the psoriatic epidermis. Archives of Dermatological Research 307: 531–538.

Article  CAS  PubMed  Google Scholar 

Kim, J.H., Y.J. Choi, B.H. Lee, M.Y. Song, C.Y. Ban, J. Kim, et al. 2016. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. The Journal of Allergy and Clinical Immunology 137: 1466–1476.

Article  CAS  PubMed  Google Scholar 

van der Fits, L., S. Mourits, J.S.A. Voerman, M. Kant, L. Boon, J. D. Laman, et al. 2009. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. Journal of Immunology (Baltimore, Md.: 1950) 182: 5836–5845.

Lin, Z.C., P.W. Hsieh, T.L. Hwang, C.Y. Chen, C.T. Sung, and J.Y. Fang. 2018. Topical application of anthranilate derivatives ameliorates psoriatic inflammation in a mouse model by inhibiting keratinocyte-derived chemokine expression and neutrophil infiltration. FASEB journal: official publication of the Federation of American Societies for Experimental Biology: fj201800354.

Strzalka, W., and A. Ziemienowicz. 2011. Proliferating cell nuclear antigen (PCNA): A key factor in DNA replication and cell cycle regulation. Annals of Botany 107: 1127–1140.

Article  CAS  PubMed  Google Scholar 

Goldminz, A.M., S.C. Au, N. Kim, A.B. Gottlieb, and P.F. Lizzul. 2013. NF-κB: An essential transcription factor in psoriasis. Journal of Dermatological Science 69: 89–94.

Article  CAS  PubMed  Google Scholar 

Roy, T., S. Banang-Mbeumi, S.T. Boateng, E.M. Ruiz, R.N. Chamcheu, L. Kang, et al. 2023. Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation. Frontiers in immunology 13: 075804.

Article  Google Scholar 

Rajagopal, D., C. Paturel, Y. Morel, S. Uematsu, S. Akira, and S.S. Diebold. 2010. Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists. Blood 115: 1949–1957.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gilliet, M., C. Conrad, M. Geiges, A. Cozzio, W. Thürlimann, G. Burg, et al. 2004. Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Archives of Dermatology 140: 1490–1495.

Article  CAS  PubMed  Google Scholar 

Casanova, J.L., J.D. MacMicking, and C.F. Nathan. 2024. Interferon-γ and infectious diseases: Lessons and prospects. Science (New York, N.Y.) 384: eadl2016.

Tian, D., and Y. Lai. 2022. The Relapse of Psoriasis: Mechanisms and Mysteries. JID innovations: Skin science from molecules to population health 2: 100116.

Article  PubMed  PubMed Central  Google Scholar 

Zhou, J., J. Zhang, L. Tao, K. Peng, Q. Zhang, K. Yan, et al. 2022. Up-regulation of BTN3A1 on CD14+ cells promotes Vγ9Vδ2 T cell activation in psoriasis. Proceedings of the National Academy of Sciences of the United States of America 119: e2117523119.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miao, X., Y. Xiang, W. Mao, Y. Chen, Q. Li, and B. Fan. 2020. TRIM27 promotes IL-6-induced proliferation and inflammation factor production by activating STAT3 signaling in HaCaT cells. American Journal of Physiology. Cell Physiology 318: C272–C281.

Article  CAS  PubMed  Google Scholar 

Prinz, I., I. Sandrock, and U. Mrowietz. 2020. Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment. The Journal of Experimental Medicine 217: e20191397.

Article  PubMed  Google Scholar 

Butte, M.J., M.E. Keir, T.B. Phamduy, A.H. Sharpe, and G.J. Freeman. 2007. Programmed death-1 ligand 1 interacts specifically with the B7–1 costimulatory molecule to inhibit T cell responses. Immunity 27: 111–122.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keir, M.E., S.C. Liang, I. Guleria, Y.E. Latchman, A. Qipo, L.A. Albacker, et al. 2006. Tissue expression of PD-L1 mediates peripheral T cell tolerance. The Journal of Experimental Medicine 203: 883–895.