Amer RM, Eltokhy AK, Elesawy RO, Barakat AN, Basha E, Eldeeb OS, Aboalsoud A, Elgharabawy NM, Ismail R (2022) The ameliorative effect of empagliflozin in vigabatrin-induced cerebellar/neurobehavioral deficits: targeting mTOR/AMPK/SIRT-1 signaling pathways. Molecules 27:3659. https://doi.org/10.3390/molecules27123659

Article  CAS  PubMed  PubMed Central  Google Scholar 

Benito-León J (2014) Essential tremor: a neurodegenerative disease? Tremor Other Hyperkinet Mov 4:252. https://doi.org/10.7916/D8765CG0

Article  Google Scholar 

Benjamin JL, Hedin CR, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG, Sanderson J, Hart AL, Kamm MA, Knight SC, Forbes A, Stagg AJ, Lindsay JO, Whelan K (2012) Smokers with active Crohn’s disease have a clinically relevant dysbiosis of the gastrointestinal microbiota. Inflamm Bowel Dis 18:1092–1100. https://doi.org/10.1002/ibd.21864

Article  PubMed  Google Scholar 

De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, Lionetti P (2010) Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 107:14691–14696. https://doi.org/10.1073/pnas.1005963107

Article  PubMed  PubMed Central  Google Scholar 

Dusart I, Guenet JL, Sotelo C (2006) Purkinje cell death: differences between developmental cell death and neurodegenerative death in mutant mice. Cerebellum 5:163–173. https://doi.org/10.1080/14734220600699373

Article  PubMed  Google Scholar 

Erekat NS (2018) Autophagy precedes apoptosis among at risk cerebellar purkinje cells in the shaker mutant rat: an ultrastructural study. Ultrastruct Pathol 42:162–169. https://doi.org/10.1080/01913123.2018.1424744

Article  PubMed  Google Scholar 

Jeffery IB, O’Toole PW, Öhman L, Claesson MJ, Deane J, Quigley EMM, Simrén M (2012) An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 61:997–1006. https://doi.org/10.1136/gutjnl-2011-301501

Article  PubMed  Google Scholar 

Kuo SH, Tang G, Ma K, Babij R, Cortes E, Vonsattel JPG, Faust PL, Sulzer D, Louis ED (2012) Macroautophagy abnormality in essential tremor. PLoS ONE 7:e53040. https://doi.org/10.1371/journal.pone.0053040

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu XJ, Wu LH, Xie WR, He XX (2020) Faecal microbiota transplantation simultaneously ameliorated patient’s essential tremor and irritable bowel syndrome. Psychogeriatrics 20:796–798. https://doi.org/10.1111/psyg.12583

Article  PubMed  PubMed Central  Google Scholar 

Louis ED, Faust PL (2020) Essential tremor pathology: neurodegeneration and reorganization of neuronal connections. Nat Rev Neurol 16:69–83. https://doi.org/10.1038/s41582-019-0302-1

Article  CAS  PubMed  Google Scholar 

Magistretti PJ (2006) Neuron-glia metabolic coupling and plasticity. J Exp Biol 209:2304–2311. https://doi.org/10.1242/jeb.02208

Article  CAS  PubMed  Google Scholar 

Mariño G, Niso-Santano M, Baehrecke EH, Kroemer G (2014) Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol 15:81–94. https://doi.org/10.1038/nrm3735

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marizzoni M, Provasi S, Cattaneo A, Frisoni GB (2017) Microbiota and neurodegenerative diseases. Curr Opin Neurol 30:630–638. https://doi.org/10.1097/WCO.0000000000000496

Article  PubMed  Google Scholar 

Matey-Hernandez ML, Williams FMK, Potter T, Valdes AM, Spector TD, Menni C (2018) Genetic and microbiome influence on lipid metabolism and dyslipidemia. Physiol Genomics 50:117–126. https://doi.org/10.1152/physiolgenomics.00053.2017

Article  CAS  PubMed  Google Scholar 

Mayer EA, Nance K, Chen S (2022) The gut-brain axis. Annu Rev Med 73:439–453. https://doi.org/10.1146/annurev-med-042320-014032

Article  CAS  PubMed  Google Scholar 

Moloney RD, Desbonnet L, Clarke G, Dinan TG, Cryan JF (2014) The microbiome: stress, health and disease. Mamm Genome 25:49–74. https://doi.org/10.1007/s00335-013-9488-5

Article  CAS  PubMed  Google Scholar 

Ng SK, Hamilton IR (1973) Carbon dioxide fixation by Veillonella parvula M 4 and its relation to propionic acid formation. Can J Microbiol 19:715–723. https://doi.org/10.1139/m73-116

Article  CAS  PubMed  Google Scholar 

Rizzatti G, Lopetuso LR, Gibiino G, Binda C, Gasbarrini A (2017) Proteobacteria: a common factor in human diseases. Biomed Res Int 2017:9351507. https://doi.org/10.1155/2017/9351507

Article  CAS  PubMed  PubMed Central  Google Scholar 

Scheiman J, Luber JM, Chavkin TA et al (2019) Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. Nat Med 25:1104–1109. https://doi.org/10.1038/s41591-019-0485-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen N, Caixàs A, Ahlers M, Patel K, Gao Z, Dutia R, Blaser MJ, Clemente JC, Laferrère B (2019) Longitudinal changes of microbiome composition and microbial metabolomics after surgical weight loss in individuals with obesity. Surg Obes Relat Dis 15:1367–1373. https://doi.org/10.1016/j.soard.2019.05.038

Article  PubMed  PubMed Central  Google Scholar 

Simpson CA, Diaz-Arteche C, Eliby D, Schwartz OS, Simmons JG, Cowan CSM (2021) The gut microbiota in anxiety and depression - a systematic review. Clin Psychol Rev 83:101943. https://doi.org/10.1016/j.cpr.2020.101943

Article  PubMed  Google Scholar 

Sun QY, He RC, Huang HY et al (2022) Age and sex affect essential tremor (ET) plus: clinical heterogeneity in ET based on the national survey in China. Aging Dis 14:1360–1373. https://doi.org/10.14336/AD.2022.1205

Article  Google Scholar 

Wahlström A, Sayin SI, Marschall H-U et al (2016) Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metab 24:41–50. https://doi.org/10.1016/j.cmet.2016.05.005

Article  CAS  PubMed  Google Scholar 

Weiss GA, Chassard C, Hennet T (2014) Selective proliferation of intestinal Barnesiella under fucosyllactose supplementation in mice. Br J Nutr 111:1602–1610. https://doi.org/10.1017/S0007114513004200

Article  CAS  PubMed  Google Scholar 

Welton T, Cardoso F, Carr JA, Chan LL, Deuschl G, Jankovic J, Tan EK (2021) Essential tremor. Nat Rev Dis Primers 7:83. https://doi.org/10.1038/s41572-021-00314-w

Article  PubMed  Google Scholar 

Wood H (2023) Gut microbiome changes linked to Parkinson disease. Nat Rev Neurol 19:3. https://doi.org/10.1038/s41582-022-00755-1

Article  PubMed  Google Scholar 

Zhang P, Huang P, Du J, He Y, Liu J, He G, Cui S, Zhang W, Li G, Chen S (2022) Specific gut microbiota alterations in essential tremor and its difference from Parkinson’s disease. NPJ Parkinsons Dis 8:98. https://doi.org/10.1038/s41531-022-00359-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou X, Zhang B, Zhao X, Lin Y, Wang J, Wang X, Hu N, Wang S (2021) Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis. Food Funct 12:5637–5649. https://doi.org/10.1039/d0fo03199b

Article  CAS  PubMed  Google Scholar