Akbarinejad V, Fathi R, Shahverdi A, Esmaeili V, Rezagholizadeh A, Ghaleno LR. The relationship of mitochondrial membrane potential, reactive oxygen species, adenosine triphosphate content, sperm plasma membrane integrity, and kinematic properties in Warmblood stallions. J Equine Vet Sci. 2020;94:103267.

Article  PubMed  Google Scholar 

Aly HA, Domenech O, Banjar ZM. Effect of nonylphenol on male reproduction: analysis of rat epididymal biochemical markers and antioxidant defense enzymes. Toxicol Appl Pharmacol. 2012;261(2):134–41. https://doi.org/10.1016/j.taap.2012.02.015.

Article  CAS  PubMed  Google Scholar 

Amir S, Shah STA, Mamoulakis C, Docea AO, Kalantzi OI, Zachariou A, et al. Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review. Int J Environ Res Public Health. 2021;18(4):1464.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cargnelutti F, Di Nisio A, Pallotti F, Sabovic I, Spaziani M, Tarsitano MG, et al. Effects of endocrine disruptors on fetal testis development, male puberty, and transition age. Endocrine. 2020;72(2):358–74.

Article  PubMed  PubMed Central  Google Scholar 

Cary CM, DeLoid GM, Yang Z, Bitounis D, Polunas M, Goedken MJ, et al. Ingested polystyrene nanospheres translocate to placenta and fetal tissues in pregnant rats: potential health implications. Nanomaterials. 2023;13(4):720.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chang WH, Liu SC, Chen HL, Lee CC. Dietary intake of 4-nonylphenol and bisphenol A in Taiwanese population: integrated risk assessment based on probabilistic and sensitive approach. Environ Pollut. 2019;244:143–52.

Article  CAS  PubMed  Google Scholar 

Chen L, Wang Z, Gu W, Zhang X, Ren H, Wu B. Single-cell sequencing reveals heterogeneity effects of bisphenol A on zebrafish embryonic development. Environ Sci Technol. 2020;54(15):9537–46.

Article  CAS  PubMed  Google Scholar 

Chen K, Wei B, Hao S, Yang W. The PI3K/AKT signaling pathway: How does it regulate development of Sertoli cells and spermatogenic cells? Histol Histopathol. 2022;37:621–36. https://doi.org/10.14670/HH-18-457.

Article  CAS  PubMed  Google Scholar 

Cheng JR, Wang K, Yu J, Yu ZX, Yu XB, Zhang ZZ. Distribution and fate modeling of 4-nonylphenol, 4-t-octylphenol, and bisphenol A in the Yong River of China. Chemosphere. 2018;195:594–605.

Article  CAS  PubMed  Google Scholar 

Chianese R, Pierantoni R. Mitochondrial reactive oxygen species (ROS) production alters sperm quality. Antioxidants. 2021;10(1):92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crane JL. Distribution and toxic potential of alkylphenols, nonylphenol ethoxylates, and pyrethroids in Minnesota, USA lake sediments. Sci Total Environ. 2021;776:145974.

Article  CAS  Google Scholar 

Dai C, Zhang Z, Shan G, Chu LT, Huang Z, Moskovtsev S, et al. Advances in sperm analysis: techniques, discoveries and applications. Nat Rev Urol. 2021;18(8):447–67.

Article  PubMed  Google Scholar 

De Bruin W, Kritzinger Q, Bornman R, Korsten L. Occurrence, fate and toxic effects of the industrial endocrine disrupter, nonylphenol, on plants - a review. Ecotoxicol Environ Saf. 2019;181:419–27.

Article  PubMed  Google Scholar 

Dong F, Ping P, Ma Y, Chen XF. Application of single-cell RNA sequencing on human testicular samples: a comprehensive review. Int J Biol Sci. 2023;19(7):2167–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duan P, Hu C, Butler HJ, Quan C, Chen W, Huang W, et al. Effects of 4-nonylphenol on spermatogenesis and induction of testicular apoptosis through oxidative stress-related pathways. Reprod Toxicol. 2016;62:27–38.

Article  CAS  PubMed  Google Scholar 

Duan P, Hu C, Quan C, Yu T, Zhou W, Yuan M, et al. 4-Nonylphenol induces apoptosis, autophagy and necrosis in Sertoli cells: Involvement of ROS-mediated AMPK/AKT-mTOR and JNK pathways. Toxicology. 2016b;341–343:28–40. https://doi.org/10.1016/j.tox.2016.01.004.

Article  CAS  PubMed  Google Scholar 

Duan P, Hu C, Butler HJ, Quan C, Chen W, Huang W, et al. 4-Nonylphenol induces disruption of spermatogenesis associated with oxidative stress-related apoptosis by targeting p53-Bcl-2/Bax-Fas/FasL signaling. Environ Toxicol. 2017a;32(3):739–53. https://doi.org/10.1002/tox.22274.

Article  CAS  PubMed  Google Scholar 

Duan P, Hu C, Quan C, Yu T, Huang W, Chen W, et al. 4-nonylphenol induces autophagy and attenuates mTOR-p70S6K/4EBP1 signaling by modulating AMPK activation in Sertoli cells. Toxicol Lett. 2017b;267:21–31.

Article  CAS  PubMed  Google Scholar 

Duan P, Liu B, Morais CLM, Zhao J, Li X, Tu J, et al. 4-nonylphenol effects on rat testis and sertoli cells determined by spectrochemical techniques coupled with chemometric analysis. Chemosphere. 2019;218:64–75.

Article  CAS  PubMed  Google Scholar 

Durairajanayagam D, Singh D, Agarwal A, Henkel R. Causes and consequences of sperm mitochondrial dysfunction. Andrologia. 2021;53(1):e13666.

Article  CAS  PubMed  Google Scholar 

Foutouhi A, Meyers S. Comparative oxidative metabolism in mammalian sperm. Anim Reprod Sci. 2022;247:107095. https://doi.org/10.1016/j.anireprosci.2022.107095.

Article  CAS  PubMed  Google Scholar 

Fu J, Akat KM, Sun Z, Zhang W, Schlondorff D, Liu Z, et al. Single-cell RNA profiling of glomerular cells shows dynamic changes in experimental diabetic kidney disease. J Am Soc Nephrol. 2019;30(4):533–45.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gallo A, Esposito MC, Tosti E, Boni R. Sperm motility, oxidative status, and mitochondrial activity: exploring correlation in different species. Antioxidants. 2021;10(7):1131.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gewaily MS, Kassab M, Farrag FA, Almadaly EA, Atta MS, Abd-Elmaksoud A, et al. Comparative expression of cell adhesion molecule1 (CADM1) in the testes of experimental mice and some farm animals. Acta Histochem. 2020. https://doi.org/10.1016/j.acthis.2019.151456.

Article  PubMed  Google Scholar 

Ghosh K, Chatterjee B, Maheswari U, Athifa M, Kanade SR. 4-nonylphenol-enhanced EZH2 and RNF2 expression, H3K27me3 and H2AK119ub1marks resulting in silencing of p21CDKN1A in vitro. Epigenomics. 2019;11(8):899–916.

Article  CAS  PubMed  Google Scholar 

Ghosh A, Tripathy A, Ghosh D. Impact of endocrine disrupting chemicals (EDCs) on reproductive health of human. Proc Zool Soc. 2022;75(1):16–30.

Article  CAS  Google Scholar 

Green CD, Q Ma, GL Manske, AN Shami, X Zheng, S Marini, et al (2018) A comprehensive roadmap of murine spermatogenesis defined by single-Cell RNA-Seq. Dev Cell 46(5): 651–667 e610. https://doi.org/10.1016/j.devcel.2018.07.025.

Gu NH, Zhao WL, Wang GS, Sun F. Comparative analysis of mammalian sperm ultrastructure reveals relationships between sperm morphology, mitochondrial functions and motility. Reprod Biol Endocrinol. 2019;17(1):66.

Article  PubMed  PubMed Central  Google Scholar 

Hamad MF. Quantification of histones and protamines mRNA transcripts in sperms of infertile couples and their impact on sperm’s quality and chromatin integrity. Reprod Biol. 2019;19(1):6–13.

Article  PubMed  Google Scholar 

Hermann BP, Cheng K, Singh A, Roa De La Cruz L, Mutoji KN, Chen IC, et al (2018) The mammalian spermatogenesis single-cell transcriptome, from spermatogonial stem cells to spermatids. Cell Rep 25(6): 1650–1667 e1658. https://doi.org/10.1016/j.celrep.2018.10.026

Huang K, Lui WY. Nectins and nectin-like molecules (Necls): Recent findings and their role and regulation in spermatogenesis. Semin Cell Dev Biol. 2016;59:54–61.

Article  CAS  PubMed  Google Scholar 

Huang P, Zhou Z, Shi F, Shao G, Wang R, Wang J, et al. Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress. Mol Med Rep. 2016;14(6):5116–24.