Moderate-to-High 5-Year Cumulative Disease Activity and Lower Bone Mineral Density at the Proximal Femur are Major Predictors of Fragility Fractures in Women with Longstanding Rheumatoid Arthritis: An Observational Cohort Study

Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E (2008) FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 19:385–397

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adami G, Saag KG (2019) Osteoporosis pathophysiology, epidemiology, and screening in rheumatoid arthritis. Curr Rheumatol Rep 21:34

Article  PubMed  Google Scholar 

Baker R, Narla R, Baker JF, Wysham KD (2022) Risk factors for osteoporosis and fractures in rheumatoid arthritis. Best Pract Res Clin Rheumatol 36:101773

Article  PubMed  Google Scholar 

Kaz Kaz H, Johnson D, Kerry S, Chinappen U, Tweed K, Patel S (2004) Fall-related risk factors and osteoporosis in women with rheumatoid arthritis. Rheumatology (Oxford) 43:1267–1271

Article  CAS  PubMed  Google Scholar 

Phuan-Udom R, Lektrakul N, Katchamart W (2018) The association between 10-year fracture risk by FRAX and osteoporotic fractures with disease activity in patients with rheumatoid arthritis. Clin Rheumatol 37:2603–2610

Article  PubMed  Google Scholar 

Kleyer A, Finzel S, Rech J, Manger B, Krieter M, Faustini F, Araujo E, Hueber AJ, Harre U, Engelke K, Schett G (2014) Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies. Ann Rheum Dis 73:854–860

Article  PubMed  Google Scholar 

Haugeberg G, Helgetveit KB, Førre Ø, Garen T, Sommerseth H, Prøven A (2014) Generalized bone loss in early rheumatoid arthritis patients followed for ten years in the biologic treatment era. BMC Musculoskelet Disord 15:289

Article  PubMed  PubMed Central  Google Scholar 

Rossini M, Adami G, Viapiana O, Idolazzi L, Orsolini G, Fassio A, Giollo A, Gatti D (2017) Osteoporosis: an independent determinant of bone erosions in rheumatoid arthritis? J Bone Miner Res 32:2142–2143

Article  PubMed  Google Scholar 

Weitzmann MN (2013) The Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis. Scientifica (Cairo) 2013:125705

PubMed  Google Scholar 

Kanis JA, WHO Study Group (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. Osteoporos Int 4:368–381

Article  CAS  PubMed  Google Scholar 

Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK (2000) Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis: results from 394 patients in the Oslo County Rheumatoid Arthritis register. Arthritis Rheum 43:522–530

Article  CAS  PubMed  Google Scholar 

Sinigaglia L, Nervetti A, Mela Q, Bianchi G, Del Puente A, Di Munno O, Frediani B, Cantatore F, Pellerito R, Bartolone S, La Montagna G, Adami S (2000) A multicenter cross sectional study on bone mineral density in rheumatoid arthritis. Italian Study Group on Bone Mass in Rheumatoid Arthritis. J Rheumatol 27:2582–2589

CAS  PubMed  Google Scholar 

Hauser B, Riches PL, Wilson JF, Horne AE, Ralston SH (2014) Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis. Rheumatology (Oxford) 53:1759–1766

Article  CAS  PubMed  Google Scholar 

Jin S, Hsieh E, Peng L, Yu C, Wang Y, Wu C, Wang Q, Li M, Zeng X (2018) Incidence of fractures among patients with rheumatoid arthritis: a systematic review and meta-analysis. Osteoporos Int 29:1263–1275

Article  CAS  PubMed  Google Scholar 

Filho JC, Pinheiro MM, de Moura Castro CH, Szejnfeld VL (2014) Prevalence and risk factors associated with low-impact fractures in men with rheumatoid arthritis. Clin Rheumatol 33:1389–1395

Article  PubMed  Google Scholar 

Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761–1767

Article  PubMed  Google Scholar 

Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Ménard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovský J, Wolfe F, Hawker G (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581

Article  PubMed  Google Scholar 

Aletaha D, Smolen J (2005) The simplified disease activity index (SDAI) and the clinical disease activity index (CDAI): a review of their usefulness and validity in rheumatoid arthritis. Clin Exp Rheumatol 23:S100-108

CAS  PubMed  Google Scholar 

Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, Kavanaugh A, McInnes IB, Solomon DH, Strand V, Yamamoto K (2018) Rheumatoid arthritis. Nat Rev Dis Primers 4:18001

Article  PubMed  Google Scholar 

Kamarudin AN, Cox T, Kolamunnage-Dona R (2017) Time-dependent ROC curve analysis in medical research: current methods and applications. BMC Med Res Methodol 17:53

Article  PubMed  PubMed Central  Google Scholar 

Nagy G, Roodenrijs NMT, Welsing PM, Kedves M, Hamar A, van der Goes MC, Kent A, Bakkers M, Blaas E, Senolt L, Szekanecz Z, Choy E, Dougados M, Jacobs JW, Geenen R, Bijlsma HW, Zink A, Aletaha D, Schoneveld L, van Riel P, Gutermann L, Prior Y, Nikiphorou E, Ferraccioli G, Schett G, Hyrich KL, Mueller-Ladner U, Buch MH, McInnes IB, van der Heijde D, van Laar JM (2021) EULAR definition of difficult-to-treat rheumatoid arthritis. Ann Rheum Dis 80:31–35

Article  PubMed  Google Scholar 

Pinheiro MM, Ciconelli RM, Martini LA, Ferraz MB (2009) Clinical risk factors for osteoporotic fractures in Brazilian women and men: the Brazilian osteoporosis study (BRAZOS). Osteoporos Int 20:399–408

Article  CAS  PubMed  Google Scholar 

Okeke T, Anyaehie U, Ezenyeaku C (2013) Premature menopause. Ann Med Health Sci Res 3:90–95

Article  PubMed  PubMed Central  Google Scholar 

Pinheiro MM, Schuch NJ, Genaro PS, Ciconelli RM, Ferraz MB, Martini LA (2009) Nutrient intakes related to osteoporotic fractures in men and women–the Brazilian Osteoporosis Study (BRAZOS). Nutr J 8:6

Article  PubMed  PubMed Central  Google Scholar 

van Poppel MN, Chinapaw MJ, Mokkink LB, van Mechelen W, Terwee CB (2010) Physical activity questionnaires for adults: a systematic review of measurement properties. Sports Med 40:565–600

Article  PubMed  Google Scholar 

Sousa MDB, Pinheiro MM, Szejnfeld VL, Castro CHM (2013) Body composition parameters in healthy Brazilian women differ from white, black, and Hispanic American women reference range. J Clin Densitom 16:360–367

Article  PubMed  Google Scholar 

Shuhart CR, Yeap SS, Anderson PA, Jankowski LG, Lewiecki EM, Morse LR, Rosen HN, Weber DR, Zemel BS, Shepherd JA (2019) Executive summary of the 2019 ISCD position development conference on monitoring treatment, DXA cross-calibration and least significant change, spinal cord injury, peri-prosthetic and orthopedic bone health, transgender medicine, and pediatrics. J Clin Densitom 22:453–471

Article  PubMed  Google Scholar 

Genant HK, Jergas M (2003) Assessment of prevalent and incident vertebral fractures in osteoporosis research. Osteoporos Int 14(Suppl 3):S43-55

Article  PubMed  Google Scholar 

Kerkeni S, Kolta S, Fechtenbaum J, Roux C (2009) Spinal deformity index (SDI) is a good predictor of incident vertebral fractures. Osteoporos Int 20:1547–1552

Article  CAS  PubMed  Google Scholar 

Fardellone P, Salawati E, Le Monnier L, Goëb V (2020) Bone loss, osteoporosis, and fractures in patients with rheumatoid arthritis: a review. J Clin Med. https://doi.org/10.3390/jcm9103361

Article  PubMed  PubMed Central  Google Scholar 

Johnell O, Kanis J (2005) Epidemiology of osteoporotic fractures. Osteoporos Int 16(Suppl 2):S3-7

Article  PubMed  Google Scholar 

Cooper C, Cole ZA, Holroyd CR, Earl SC, Harvey NC, Dennison EM, Melton LJ, Cummings SR, Kanis JA, Epidemiology ICWGoF (2011) Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporos Int 22:1277–1288

Article  CAS 

Comments (0)

No login
gif