Alexopoulos N, Raggi P (2009) Calcification in atherosclerosis. Nat Rev Cardiol 6(11):681–688

Article  CAS  PubMed  Google Scholar 

Bakhshian Nik A, Hutcheson JD, Aikawa E (2017) Extracellular vesicles as mediators of cardiovascular calcification. Front Cardiovasc Med 4:78

Article  PubMed  PubMed Central  Google Scholar 

Basak T, Tanwar VS, Bhardwaj G, Bhardwaj N, Ahmad S, Garg GVS, Karthikeyan G, Seth S, Sengupta S (2016) Plasma proteomic analysis of stable coronary artery disease indicates impairment of reverse cholesterol pathway. Sci Rep 6:28042

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q (2011) Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression. Mol Cancer 10:106

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blaha M, Budoff MJ, Shaw LJ, Khosa F, Rumberger JA, Berman D, Callister T, Raggi P, Blumenthal RS, Nasir K (2009) Absence of coronary artery calcification and all-cause mortality. JACC Cardiovasc Imaging 2(6):692–700

Article  PubMed  Google Scholar 

Bowman MAH, McNally EM (2012) Genetic pathways of vascular calcification. Trends Cardiovasc Med 22(4):93–98

Article  PubMed Central  Google Scholar 

Broeders W, Bekkering S, El Messaoudi S, Joosten LA, van Royen N, Riksen NP (2022) Innate immune cells in the pathophysiology of calcific aortic valve disease: lessons to be learned from atherosclerotic cardiovascular disease? Basic Res Cardiol 117(1):1–22

Article  Google Scholar 

Bu-Chun Z, Xiangdong K, GuangQuan Q, LongWei L, Lian M (2022) Proteomic analysis of serum proteins from patients with severe coronary artery calcification. Rev Cardiovasc Med 6:66

Google Scholar 

Budoff M (2006) Aged garlic extract retards progression of coronary artery calcification. J Nutr 136(3):741S-744S

Article  CAS  PubMed  Google Scholar 

Carracedo M, Witasp A, Qureshi A, Laguna-Fernandez A, Brismar T, Stenvinkel P, Bäck M (2019) Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease. J Intern Med 286(4):449–457

Article  CAS  PubMed  PubMed Central  Google Scholar 

Coelho R, Ricardo S, Amaral AL, Huang Y-L, Nunes M, Neves JP, Mendes N, López MN, Bartosch C, Ferreira V et al (2020) Regulation of invasion and peritoneal dissemination of ovarian cancer by mesothelin manipulation. Oncogenesis 9(6):61

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ding D, Min W, Dongfang S, Chang-jiang H, Xinrui L, Yuan Z, Gang H, Wenhua L (2015) Abstract P255: body mass index, C-reactive protein and mortality among coronary artery disease patients. Circulation 6:66

Google Scholar 

Egaña-Gorroño L, López-Díez R, Yepuri G, Ramirez LS, Reverdatto S, Gugger PF, Shekhtman A, Ramasamy R, Schmidt AM (2020) Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human subjects and animal models. Front Cardiovasc Med 7:37

Article  PubMed  PubMed Central  Google Scholar 

Ekdahl KN, Soveri I, Hilborn J, Fellström B, Nilsson B (2017) Cardiovascular disease in haemodialysis: role of the intravascular innate immune system. Nat Rev Nephrol 13(5):285–296

Article  CAS  PubMed  Google Scholar 

Genest J Jr, Bard JM, Fruchart JC, Ordovas JM, Schaefer EJ (1993) Familial hypoalphalipoproteinemia in premature coronary artery disease. Arterioscler Thromb 13(12):1728–1737

Article  PubMed  Google Scholar 

Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR (1977) High density lipoprotein as a protective factor against coronary heart disease: the Framingham study. Am J Med 62(5):707–714

Article  CAS  PubMed  Google Scholar 

Gupta A, Lau E, Varshney R, Hulten EA, Cheezum M, Bittencourt MS, Blaha MJ, Wong ND, Blumenthal RS, Budoff MJ (2017) The identification of calcified coronary plaque is associated with initiation and continuation of pharmacological and lifestyle preventive therapies: a systematic review and meta-analysis. JACC Cardiovasc Imaging 10(8):833–842

Article  PubMed  PubMed Central  Google Scholar 

Hansson GK, Holm J, Jonasson L (1989) Detection of activated T lymphocytes in the human atherosclerotic plaque. Am J Pathol 135(1):169–175

CAS  PubMed  PubMed Central  Google Scholar 

Jamila K-L, Giuseppina C, Emilie G, Tupin E, Anh-Thu G, Bruno P, Mitchell K, José LC, David K, Srini VK et al (2006) The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease. Arterioscler Thrombos Vasc Biol 6:66

Google Scholar 

Karin PMvG, Tuinenburg A, Emma MS, Roger EGS (2012) Von Willebrand factor deficiency and atherosclerosis. Blood Rev 6:66

Google Scholar 

Kopp A, Bala M, Buechler C, Falk W, Gross P, Neumeier M, Scholmerich J, Schaffler A (2010) C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue. Endocrinology 151(11):5267–5278

Article  CAS  PubMed  Google Scholar 

Kyavar M, Alemzadeh-Ansari MJ (2022) Chapter 24—stable ischemic heart disease. In: Maleki M, Alizadehasl A, Haghjoo M (eds) Practical cardiology, 2nd edn. Elsevier, Amsterdam, pp 429–453

Chapter  Google Scholar 

Laakmann K, Eckersberg JM, Hapke M, Wiegand M, Bierwagen J, Beinborn I, Preußer C, Pogge von Strandmann E, Heimerl T, Schmeck B et al (2023) Bacterial extracellular vesicles repress the vascular protective factor RNase1 in human lung endothelial cells. Cell Commun Signal 21(1):111

Article  CAS  PubMed  PubMed Central  Google Scholar 

Laura H, Trang TDL, Beate B, Jaber M, Markus PS, Sebastian B, Florian L, Burkert P, Andreas P, Kai-Uwe E et al (2019) Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. Aging 6:66

Google Scholar 

Lin X, Li S, Wang Y-J, Wang Y, Zhong J-Y, He J-Y, Cui X-J, Zhan J-K, Liu Y-S (2019) Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging. Life Sci 232:116582

Article  CAS  PubMed  Google Scholar 

Lindsey ML, Mayr M, Gomes AV, Delles C, Arrell DK, Murphy AM, Lange RA, Costello CE, Jin YF, Laskowitz DT et al (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation 132(9):852–872

Article  CAS  PubMed  Google Scholar 

Liu Y, Wang T, Yan J, Jiagbogu N, Heideman DA, Canfield AE, Alexander MY (2011) HGF/c-Met signalling promotes Notch3 activation and human vascular smooth muscle cell osteogenic differentiation in vitro. Atherosclerosis 219(2):440–447

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Z, Li J, Liu H, Tang Y, Zhan Q, Lai W, Ao L, Meng X, Ren H, Xu D (2019) The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease. Atherosclerosis 284:121–128

Article  CAS  PubMed  Google Scholar 

Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ (2006) Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367(9524):1747–1757

Article  PubMed  Google Scholar 

Mahmoud AM, Jones AM, Sidgwick GP, Arafat AM, Alexander YM, Wilkinson FL (2019) Small molecule glycomimetics inhibit vascular calcification via c-Met/Notch3/HES1 signalling. Cell Physiol Biochem 53(2):323–336

Article  CAS  PubMed  Google Scholar 

Martin SS, Qasim AN, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N, Schutta M, Bagheri R, Reilly MP (2009) Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites. Diabetes 58(8):1887–1892

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martínez-López D, Roldan-Montero R, García-Marqués F, Nuñez E, Jorge I, Camafeita E, Minguez P, Rodriguez de Cordoba S, López-Melgar B, Lara-Pezzi E (2020) Complement C5 protein as a marker of subclinical atherosclerosis. J Am Coll Cardiol 75(16):1926–1941

Article  PubMed  Google Scholar 

Members WC, Virani SS, Newby LK, Arnold SV, Bittner V, Brewer LC, Demeter SH, Dixon DL, Fearon WF, Hess B (2023) 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary disease: a report of the American Heart Association/America