Stark, K. & Massberg, S. Interplay between inflammation and thrombosis in cardiovascular pathology. Nat. Rev. Cardiol. 18, 666–682 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Esmon, C. T. Molecular circuits in thrombosis and inflammation. Thromb. Haemost. 109, 416–420 (2013).

Article  CAS  PubMed  Google Scholar 

Engelmann, B. & Massberg, S. Thrombosis as an intravascular effector of innate immunity. Nat. Rev. Immunol. 13, 34–45 (2012).

Article  PubMed  Google Scholar 

Khorana, A. A. et al. Cancer-associated venous thromboembolism. Nat. Rev. Dis. Prim. 8, 1–18 (2022).

Google Scholar 

Mackman, N. et al. Coagulation abnormalities and thrombosis in patients infected with SARS-CoV-2 and other pandemic viruses. Arterioscler. Thromb. Vasc. Biol. 40, 2033–2044 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rittirsch, D., Flierl, M. A. & Ward, P. A. Harmful molecular mechanisms in sepsis. Nat. Rev. Immunol. 8, 776–787 (2008).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Emmi, G. et al. Thrombosis in vasculitis: from pathogenesis to treatment. Thromb. J. 13, 15 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Sherer, Y. & Shoenfeld, Y. Mechanisms of disease: atherosclerosis in autoimmune diseases. Nat. Clin. Pract. Rheumatol. 2, 99–106 (2006).

Article  CAS  PubMed  Google Scholar 

Phillip R., Luqmani, R. Mortality in systemic vasculitis: a systematic review. Clin. Exp. Rheumatol. 26, S94–104 (2008).

CAS  PubMed  Google Scholar 

Della Rossa, A., Tavoni, A. & Bombardieri, S. Hyperviscosity syndrome in cryoglobulinemia: clinical aspects and therapeutic considerations. Semin. Thromb. Hemost. 29, 473–477 (2003).

Article  PubMed  Google Scholar 

Kuramochi, Y. et al. Hemodynamic factors of thrombus formation in coronary aneurysms associated with Kawasaki disease. Pediatrics Int. 42, 470–475 (2000).

Article  CAS  Google Scholar 

Du, L. et al. Multisystemic manifestations of IgA vasculitis. Clin. Rheumatol. 40, 43–52 (2021).

Article  CAS  PubMed  Google Scholar 

Kitching, A. R. et al. ANCA-associated vasculitis. Nat. Rev. Dis. Prim. 6, 71 (2020).

Article  PubMed  Google Scholar 

Rathmann, J. et al. Stable incidence but increase in prevalence of ANCA-associated vasculitis in southern Sweden: a 23-year study. RMD Open 9, e002949 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Hellmich, B. et al. EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. Ann. Rheum. Dis. 83, 30–47 (2024).

Article  PubMed  Google Scholar 

Moiseev, S. et al. Traditional and disease-specific risk factors for cardiovascular events in antineutrophil cytoplasmic antibody-associated vasculitis: a multinational retrospective study. J. Rheumatol. 50, 1145–1151 (2023).

Article  PubMed  Google Scholar 

Mohammad, A. J. et al. Rate of comorbidities in giant cell arteritis: a population-based study. J. Rheumatol. 44, 84–90 (2017).

Article  PubMed  Google Scholar 

Kronbichler, A. et al. Comorbidities in ANCA-associated vasculitis. Rheumatology 59 (Suppl. 3), iii79–iii83 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sánchez Álamo, B. et al. Long-term outcomes and prognostic factors for survival of patients with ANCA-associated vasculitis. Nephrol. Dial. Transplant. 38, 1655–1665 (2023).

Article  PubMed  Google Scholar 

Tan, J. A. et al. Mortality in ANCA-associated vasculitis: a meta-analysis of observational studies. Ann. Rheum. Dis. 76, 1566–1574 (2017).

Article  PubMed  Google Scholar 

Flossmann, O. et al. Long-term patient survival in ANCA-associated vasculitis. Ann. Rheum. Dis. 70, 488–494 (2011).

Article  PubMed  Google Scholar 

Bettiol, A. et al. Risk of acute arterial and venous thromboembolic events in eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome). Eur. Respir. J. 57, 2004158 (2021).

Article  CAS  PubMed  Google Scholar 

Allenbach, Y. et al. High frequency of venous thromboembolic events in Churg-Strauss syndrome, Wegener’s granulomatosis and microscopic polyangiitis but not polyarteritis nodosa: a systematic retrospective study on 1130 patients. Ann. Rheum. Dis. 68, 564–567 (2009).

Article  CAS  PubMed  Google Scholar 

Clifford, A. H. & Cohen Tervaert, J. W. Cardiovascular events and the role of accelerated atherosclerosis in systemic vasculitis. Atherosclerosis 325, 8–15 (2021).

Article  CAS  PubMed  Google Scholar 

Go, A. S. Cardiovascular disease consequences of CKD. Semin. Nephrol. 36, 293–304 (2016).

Article  PubMed  Google Scholar 

Moiseev, S. et al. End-stage renal disease in ANCA-associated vasculitis. Nephrol. Dial. Transplant. 32, 248–253 (2017).

CAS  PubMed  Google Scholar 

Liapi, M. et al. Venous thromboembolism in ANCA-associated vasculitis: a population-based cohort study. Rheumatology 60, 4616–4623 (2021).

Article  CAS  PubMed  Google Scholar 

Tabakovic, D. et al. High risk of stroke in ANCA-associated vasculitis-a population-based study. Rheumatology 62, 2806–2812 (2023).

Article  PubMed  Google Scholar 

Armbruster, A. L. et al. The role of inflammation in the pathogenesis and treatment of arrhythmias. Pharmacotherapy 42, 250–262 (2022).

Article  CAS  PubMed  Google Scholar 

Vegting, Y. et al. Traditional and disease-related cardiovascular risk factors in ANCA-associated vasculitis: a prospective, two-centre cohort study. Joint Bone Spine 90, 105540 (2023).

Article  PubMed  Google Scholar 

Moiseev, S. et al. Association of venous thromboembolic events with skin, pulmonary and kidney involvement in ANCA-associated vasculitis: a multinational study. Rheumatology 60, 4654–4661 (2021).

Article  CAS  PubMed  Google Scholar 

Busch, M. H. et al. The intrinsic coagulation pathway plays a dominant role in driving hypercoagulability in ANCA-associated vasculitis. Blood Adv. 8, 1295–1304 (2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Go, E. et al. Von Willebrand factor antigen as a marker of disease activity in childhood-onset antineutrophil cytoplasmic antibody–associated vasculitis. Rheumatology 63 (SI2), SI228–SI232 (2024).

Article  PubMed  Google Scholar 

van Zaane, B. et al. Systematic review on the effect of glucocorticoid use on procoagulant, anti‐coagulant and fibrinolytic factors. J. Thromb. Haemost. 8, 2483–2493 (2010).

Article  PubMed  Google Scholar 

Sartorelli, S. et al. Revisiting characteristics, treatment and outcome of cardiomyopathy in eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss). Rheumatology 61, 1175–1184 (2022).

Article  CAS