Vergallo R, Crea F. Atherosclerotic Plaque Healing. N Engl J Med. 2020;383(9):846–57.

Article  CAS  PubMed  Google Scholar 

Libby P. The changing landscape of atherosclerosis. Nature aprile. 2021;592(7855):524–33.

Article  CAS  Google Scholar 

Libby P. Inflammation and the pathogenesis of atherosclerosis. Vascul Pharmacol marzo. 2024;154:107255.

Article  CAS  Google Scholar 

Franceschi C, Garagnani P, Parini P, Giuliani C, Santoro A. Inflammaging: a new immune-metabolic viewpoint for age-related diseases. Nat Rev Endocrinol ottobre. 2018;14(10):576–90.

Article  CAS  Google Scholar 

Liberale L, Montecucco F, Tardif JC, Libby P, Camici GG. Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease. Eur Heart J. 2020;41(31):2974–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kraler S, Libby P, Evans PC, Akhmedov A, Schmiady MO, Reinehr M, et al. Resilience of the Internal Mammary Artery to Atherogenesis: Shifting From Risk to Resistance to Address Unmet Needs. Arterioscler Thromb Vasc Biol agosto. 2021;41(8):2237–51.

Article  CAS  Google Scholar 

Neeland IJ, Poirier P, Després JP. Cardiovascular and Metabolic Heterogeneity of Obesity: Clinical Challenges and Implications for Management. Circulation. 2018;137(13):1391–406.

Article  PubMed  PubMed Central  Google Scholar 

Ramoni D, Scuricini A, Liberale L, Montecucco F, Carbone F. Insights into beige phenotype and immune cell dynamics of human epicardial adipose tissue. Obes Silver Spring Md luglio. 2024;32(7):1231–2.

Article  CAS  Google Scholar 

Verhaar BJH, Prodan A, Nieuwdorp M, Muller M. Gut Microbiota in Hypertension and Atherosclerosis: A Review. Nutrients. 2020;12(10):2982.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liberale L, Montecucco F, Schwarz L, Lüscher TF, Camici GG. Inflammation and cardiovascular diseases: lessons from seminal clinical trials. Cardiovasc Res. 2021;117(2):411–22.

Article  CAS  PubMed  Google Scholar 

Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation. 2005;111(25):3481–8.

Article  PubMed  Google Scholar 

Chang HJ, Lin FY, Lee SE, Andreini D, Bax J, Cademartiri F, et al. Coronary Atherosclerotic Precursors of Acute Coronary Syndromes. J Am Coll Cardiol. 2018;71(22):2511–22.

Article  PubMed  PubMed Central  Google Scholar 

Bentzon JF, Otsuka F, Virmani R, Falk E. Mechanisms of plaque formation and rupture. Circ Res. 2014;114(12):1852–66.

Article  CAS  PubMed  Google Scholar 

Falk E, Nakano M, Bentzon JF, Finn AV, Virmani R. Update on acute coronary syndromes: the pathologists’ view. Eur Heart J marzo. 2013;34(10):719–28.

Article  CAS  Google Scholar 

Fahed AC, Jang IK. Plaque erosion and acute coronary syndromes: phenotype, molecular characteristics and future directions. Nat Rev Cardiol ottobre. 2021;18(10):724–34.

Article  Google Scholar 

Liberale L, Carbone F, Montecucco F, Gebhard C, Lüscher TF, Wegener S, et al. Ischemic stroke across sexes: What is the status quo? Front Neuroendocrinol luglio. 2018;50:3–17.

Article  Google Scholar 

Kubo T, Imanishi T, Takarada S, Kuroi A, Ueno S, Yamano T, et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J Am Coll Cardiol. 2007;50(10):933–9.

Article  PubMed  Google Scholar 

Baaten CCFMJ, Nagy M, Bergmeier W, Spronk HMH, van der Meijden PEJ. Platelet biology and function: plaque erosion vs rupture. Eur Heart J. 2024;45(1):18–31.

Article  CAS  PubMed  Google Scholar 

Kiss MG, Binder CJ. The multifaceted impact of complement on atherosclerosis. Atherosclerosis giugno. 2022;351:29–40.

Article  CAS  Google Scholar 

Arlaud GJ, Biro A, Ling WL. Enzymatically modified low-density lipoprotein is recognized by c1q and activates the classical complement pathway. J Lipids. 2011;2011:376092.

Article  PubMed  PubMed Central  Google Scholar 

Hertle E, van Greevenbroek MM, Arts IC, van der Kallen CJ, Geijselaers SL, Feskens EJ, et al. Distinct associations of complement C3a and its precursor C3 with atherosclerosis and cardiovascular disease. The CODAM study Thromb Haemost giugno. 2014;111(6):1102–11.

Article  CAS  Google Scholar 

Speidl WS, Exner M, Amighi J, Kastl SP, Zorn G, Maurer G, et al. Complement component C5a predicts future cardiovascular events in patients with advanced atherosclerosis. Eur Heart J novembre. 2005;26(21):2294–9.

Article  CAS  Google Scholar 

Nonaka M, Kimura A. Genomic view of the evolution of the complement system. Immunogenetics settembre. 2006;58(9):701–13.

Article  CAS  Google Scholar 

Schulz K, Donat C, Punjabi M, Glatz K, Kaufmann B, Trendelenburg M. Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery. Front Immunol. 2023;14:1265387.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao W, Bobryshev YV, Lord RSA, Oakley REI, Lee SH, Lu J. Dendritic cells in the arterial wall express C1q: potential significance in atherogenesis. Cardiovasc Res. 2003;60(1):175–86.

Article  CAS  PubMed  Google Scholar 

Sasaki S, Nishihira K, Yamashita A, Fujii T, Onoue K, Saito Y, et al. Involvement of enhanced expression of classical complement C1q in atherosclerosis progression and plaque instability: C1q as an indicator of clinical outcome. PLoS ONE. 2022;17(1):e0262413.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carbone F, Valente A, Perego C, Bertolotto M, Pane B, Spinella G, et al. Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis. Pharmacol Res aprile. 2021;166:105462.

Article  CAS  Google Scholar 

Fumagalli S, Perego C, Zangari R, De Blasio D, Oggioni M, De Nigris F, et al. Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques. Front Immunol. 2017;8:288.

Article  PubMed  PubMed Central  Google Scholar 

Kraler S, Wenzl FA, Georgiopoulos G, Obeid S, Liberale L, von Eckardstein A, et al. Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes. Eur Heart J. 2022;43(19):1849–60.

Article  CAS  PubMed  Google Scholar 

Akhmedov A, Sawamura T, Chen CH, Kraler S, Vdovenko D, Lüscher TF. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1): a crucial driver of atherosclerotic cardiovascular disease. Eur Heart J. 2021;42(18):1797–807.

Article  CAS  PubMed  Google Scholar 

Bhakdi S, Torzewski M, Klouche M, Hemmes M. Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation. Arterioscler Thromb Vasc Biol ottobre. 1999;19(10):2348–54.

Article  CAS  Google Scholar 

Pilely K, Fumagalli S, Rosbjerg A, Genster N, Skjoedt MO, Perego C, et al. C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques. Front Immunol. 2017;8:1040.

Article  PubMed  PubMed Central  Google Scholar 

Garcia-Arguinzonis M, Diaz-Riera E, Peña E, Escate R, Juan-Babot O, Mata P, et al. Alternative C3 Complement System: Lipids and Atherosclerosis. Int J Mol Sci. 2021;22(10):5122.

Article  CAS  PubMed