Soares S, Sousa J, Pais A, Vitorino C. Nanomedicine: principles, properties, and regulatory issues. Front Chem. 2018;6:360. https://doi.org/10.3389/fchem.2018.00360.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tinkle S, McNeil SE, Mühlebach S, Bawa R, Borchard G, Barenholz YC, Tamarkin L, Desai N. Nanomedicines: addressing the scientific and regulatory gap. Ann N Y Acad Sci. 2014;1313:35–56. https://doi.org/10.1111/nyas.12403.

Article  PubMed  CAS  Google Scholar 

Patra JK, Das G, Fraceto LF, Campos EVR, Rodriguez-Torres MDP, Acosta-Torres LS, Diaz-Torres LA, Grillo R, Swamy MK, Sharma S, Habtemariam S, Shin HS. Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnol. 2018;16(1):71. https://doi.org/10.1186/s12951-018-0392-8.

Article  CAS  Google Scholar 

Singh A, Amiji MM. Application of nanotechnology in medical diagnosis and imaging. Curr Opin Biotechnol. 2022;74:241–6. https://doi.org/10.1016/j.copbio.2021.12.011.

Article  PubMed  CAS  Google Scholar 

Dong Y, Wu X, Chen X, Zhou P, Xu F, Liang W. Nanotechnology shaping stem cell therapy: recent advances, application, challenges, and future outlook. Biomed Pharmacother. 2021;137:111236. https://doi.org/10.1016/j.biopha.2021.111236.

Article  PubMed  CAS  Google Scholar 

Qamar Z, Qizilbash FF, Iqubal MK, Ali A, Narang JK, Ali J, Baboota S. Nano-based drug delivery system: recent strategies for the treatment of ocular disease and future perspective. Recent Pat Drug Deliv Formul. 2019;13(4):246–54. https://doi.org/10.2174/1872211314666191224115211.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Khiev D, Mohamed ZA, Vichare R, Paulson R, Bhatia S, Mohapatra S, Lobo GP, Valapala M, Kerur N, Passaglia CL, Mohapatra SS, Biswal MR. Emerging nano-formulations and nanomedicines applications for ocular drug delivery. Nanomaterials (Basel, Switzerland). 2021;11(1):173. https://doi.org/10.3390/nano11010173Shen.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Shen Y, Sun J, Sun X. Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress. J Nanobiotechnol. 2023;21(1):84. https://doi.org/10.1186/s12951-023-01838-x.

Article  Google Scholar 

Sanap SN, Bisen AC, Agrawal S, Kedar A, Bhatta RS. Ophthalmic nano-bioconjugates: critical challenges and technological advances. Ther Deliv. 2023;14(7):419–41. https://doi.org/10.4155/tde-2023-0031.

Article  PubMed  CAS  Google Scholar 

Liu LC, Chen YH, Lu DW. Overview of recent advances in nano-based ocular drug delivery. Int J Mol Sci. 2023;24(20):15352. https://doi.org/10.3390/ijms242015352.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wu KY, Ashkar S, Jain S, Marchand M, Tran SD. Breaking barriers in eye treatment: polymeric nano-based drug-delivery system for anterior segment diseases and glaucoma. Polymers. 2023;15(6):1373. https://doi.org/10.3390/polym15061373.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Choi G, Song Y, Lim H, Lee SH, Lee HK, Lee E, Choi BG, Lee JJ, Im SG, Lee KG. Antibacterial nanopillar array for an implantable intraocular lens. Adv Healthc Mater. 2020;9(18): e2000447. https://doi.org/10.1002/adhm.202000447.

Article  PubMed  CAS  Google Scholar 

Fang Y, Zhuo L, Yuan H, Zhao H, Zhang L. Construction of graphene quantum dot-based dissolving microneedle patches for the treatment of bacterial keratitis. Int J Pharm. 2023;639: 122945. https://doi.org/10.1016/j.ijpharm.2023.122945.

Article  PubMed  CAS  Google Scholar 

Huang K, Liu X, Lv Z, Zhang D, Zhou Y, Lin Z, Guo J. MMP9-responsive graphene oxide quantum dot-based nano-in-micro drug delivery system for combinatorial therapy of choroidal neovascularization. Small. 2023;19(39): e2207335. https://doi.org/10.1002/smll.202207335.

Article  PubMed  CAS  Google Scholar 

Wei J, Mu J, Tang Y, Qin D, Duan J, Wu A. Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy. J Nanobiotechnol. 2023;21(1):282. https://doi.org/10.1186/s12951-023-01974-4.

Article  Google Scholar 

Luo L, Yang J, Oh Y, Hartsock MJ, Xia S, Kim YC, Ding Z, Meng T, Eberhart CG, Ensign LM, Thorne JE, Stark WJ, Duh EJ, Xu Q, Hanes J. Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis. J Control Release: Off J Control Release Soc. 2019;296:68–80. https://doi.org/10.1016/j.jconrel.2019.01.018.

Article  CAS  Google Scholar 

Chen F, Si P, de la Zerda A, Jokerst JV, Myung D. Gold nanoparticles to enhance ophthalmic imaging. Biomater Sci. 2021;9(2):367–90. https://doi.org/10.1039/d0bm01063d.

Article  PubMed  CAS  Google Scholar 

Kumar VB, Sher I, Rencus-Lazar S, Rotenstreich Y, Gazit E. Functional carbon quantum dots for ocular imaging and therapeutic applications. Small. 2023;19(7): e2205754. https://doi.org/10.1002/smll.202205754.

Article  PubMed  CAS  Google Scholar 

Sarwat S, Stapleton F, Willcox M, Roy M. Quantum dots in ophthalmology: a literature review. Curr Eye Res. 2019;44(10):1037–46. https://doi.org/10.1080/02713683.2019.1660793.

Article  PubMed  CAS  Google Scholar 

Li Y, Lu S, Zhang Y, Li J, Xiong L. High-resolution imaging of the ocular vasculature of conjunctivitis in mice using highly bright polymer dots. Adv Healthc Mater. 2022;11(21): e2200978. https://doi.org/10.1002/adhm.202200978.

Article  PubMed  CAS  Google Scholar 

Sakpal D, Gharat S, Momin M. Recent advancements in polymeric nanofibers for ophthalmic drug delivery and ophthalmic tissue engineering. Biomater Adv. 2022;141: 213124. https://doi.org/10.1016/j.bioadv.2022.213124.

Article  PubMed  CAS  Google Scholar 

Gusev AA, Zakharova OV, Vasyukova IA, Osmanov RE, Al-Makhdar YM. Nanotekhnologii v oftal’mologii [Nanotechnologies in ophthalmology]. Vestn oftalmol. 2023;139(4):107–14. https://doi.org/10.17116/oftalma2023139041107.

Article  PubMed  CAS  Google Scholar 

Sahle FF, Kim S, Niloy KK, Tahia F, Fili CV, Cooper E, Hamilton DJ, Lowe TL. Nanotechnology in regenerative ophthalmology. Adv Drug Deliv Rev. 2019;148:290–307. https://doi.org/10.1016/j.addr.2019.10.006. (oftal'mologii [Nanotechnologies in ophthalmology]. Vestnik oftalmologii, 139(4), 107–114. https://doi.org/10.17116/oftalma2023139041107 ).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang J, Tao Z, Deng H, Cui Y, Xu Z, Lyu Q, Zhao J. Therapeutic implications of nanodrug and tissue engineering for retinal pigment epithelium-related diseases. Nanoscale. 2022;14(15):5657–77. https://doi.org/10.1039/d1nr08337f.

Article  PubMed  CAS  Google Scholar 

Chen H, Yang J, Sun L, Zhang H, Guo Y, Qu J, Jiang W, Chen W, Ji J, Yang YW, Wang B. Synergistic chemotherapy and photodynamic therapy of endophthalmitis mediated by zeolitic imidazolate framework-based drug delivery systems. Small. 2019;15(47): e1903880. https://doi.org/10.1002/smll.201903880.

Article  PubMed  CAS  Google Scholar 

Zhang H, Jiang W, Peng Y, Yang J, Chu X, Long Z, Li R, Liang Q, Suo H, Wang S, Yang M, Qi J, Ding D, Yang YW, Wang B. Killing three birds with one stone: near-infrared light triggered nitric oxide release for enhanced photodynamic and anti-inflammatory therapy in refractory keratitis. Biomaterials. 2022;286: 121577. https://doi.org/10.1016/j.biomaterials.2022.121577.

Article  PubMed  CAS  Google Scholar 

Zheng X, Shi Y, Tang D, Xiao H, Shang K, Zhou X, Tan G. Near-Infrared-II Nanoparticles for Vascular Normalization Combined with Immune Checkpoint Blockade via Photodynamic Immunotherapy Inhibit Uveal Melanoma Growth and Metastasis. Adv Sci (Weinheim, Baden-Wurttemberg, Germany). 2023;10(35): e2206932. https://doi.org/10.1002/advs.202206932.

Article  CAS