Dalbeth N, Gosling AL, Gaffo A, Abhishek A (2021) Gout Lancet 397:1843–1855. https://doi.org/10.1016/S0140-6736(21)00569-9

Article  CAS  PubMed  Google Scholar 

Tan Y, Fu Y, Yao H et al (2023) Relationship between phthalates exposures and hyperuricemia in U.S. general population, a multi-cycle study of NHANES 2007–2016. Sci Total Environ 859:160208. https://doi.org/10.1016/j.scitotenv.2022.160208

Article  CAS  PubMed  Google Scholar 

Chen-Xu M, Yokose C, Rai SK et al (2019) Contemporary prevalence of gout and Hyperuricemia in the United States and Decadal trends: the National Health and Nutrition Examination Survey, 2007–2016. Arthritis Rheumatol 71:991–999. https://doi.org/10.1002/art.40807

Article  PubMed  PubMed Central  Google Scholar 

He H, Pan L, Ren X et al (2022) The Effect of Body Weight and Alcohol Consumption on Hyperuricemia and their Population attributable fractions: a National Health Survey in China. Obes Facts 15:216–227. https://doi.org/10.1159/000521163

Article  CAS  PubMed  Google Scholar 

Ben-Dov IZ, Kark JD (2011) Serum uric acid is a GFR-independent long-term predictor of acute and chronic renal insufficiency: the Jerusalem Lipid Research Clinic cohort study. Nephrol Dialysis Transplantation 26:2558–2566. https://doi.org/10.1093/ndt/gfq740

Article  CAS  Google Scholar 

Borghi C, Agabiti-Rosei E, Johnson RJ et al (2020) Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease. Eur J Intern Med 80:1–11. https://doi.org/10.1016/j.ejim.2020.07.006

Article  CAS  PubMed  Google Scholar 

Yu K, See L, Huang Y et al (2008) Dietary factors associated with hyperuricemia in adults. Semin Arthritis Rheum 37:243–250. https://doi.org/10.1016/j.semarthrit.2007.04.007

Article  CAS  PubMed  Google Scholar 

Yokose C, McCormick N, Choi HK (2021) The role of diet in hyperuricemia and gout. Curr Opin Rheumatol 33:135–144. https://doi.org/10.1097/BOR.0000000000000779

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gaffo AL, Saag KG (2008) Management of hyperuricemia and gout in CKD. Am J Kidney Dis 52:994–1009. https://doi.org/10.1053/j.ajkd.2008.07.035

Article  PubMed  Google Scholar 

Guo H, Wang S, Peng H et al (2023) Dose-response relationships of tea and coffee consumption with gout: a prospective cohort study in the UK Biobank. Rheumatology (Oxford) 62:3043–3050. https://doi.org/10.1093/rheumatology/kead019

Article  PubMed  Google Scholar 

ALRashdi BM, Elgebaly HA, Germoush MO et al (2022) A flavonoid-rich fraction of Monolluma quadrangula inhibits xanthine oxidase and ameliorates potassium oxonate-induced hyperuricemia in rats. Environ Sci Pollut Res Int 29:63520–63532. https://doi.org/10.1007/s11356-022-20274-2

Article  CAS  PubMed  Google Scholar 

Chen Y, Luo L, Hu S et al (2022) The chemistry, processing, and preclinical anti-hyperuricemia potential of tea: a comprehensive review. Crit Rev Food Sci Nutr 1–26. https://doi.org/10.1080/10408398.2022.2040417

Dobrijević D, Pastor K, Nastić N et al (2023) Betaine as a functional ingredient: metabolism, Health-promoting attributes, Food sources, applications and analysis methods. Molecules 28:4824. https://doi.org/10.3390/molecules28124824

Article  CAS  PubMed  PubMed Central  Google Scholar 

Craig SAS (2004) Betaine in human nutrition. Am J Clin Nutr 80:539–549. https://doi.org/10.1093/ajcn/80.3.539

Article  CAS  PubMed  Google Scholar 

Ueland PM (2011) Choline and betaine in health and disease. J Inherit Metab Dis 34:3–15. https://doi.org/10.1007/s10545-010-9088-4

Article  CAS  PubMed  Google Scholar 

Lewis AS, Murphy L, McCalla C et al (1984) Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin. J Biol Chem 259:12–15

Article  CAS  PubMed  Google Scholar 

Fan C-Y, Wang M-X, Ge C-X et al (2014) Betaine supplementation protects against high-fructose-induced renal injury in rats. J Nutr Biochem 25:353–362. https://doi.org/10.1016/j.jnutbio.2013.11.010

Article  CAS  PubMed  Google Scholar 

Jorgačević B, Stanković S, Filipović J et al (2022) Betaine modulating MIF-Mediated oxidative stress, inflammation and fibrogenesis in Thioacetamide-Induced Nephrotoxicity. Curr Med Chem 29:5254–5267. https://doi.org/10.2174/0929867329666220408102856

Article  CAS  PubMed  Google Scholar 

Liu Y-L, Pan Y, Wang X et al (2014) Betaine reduces serum uric acid levels and improves kidney function in hyperuricemic mice. Planta Med 80:39–47. https://doi.org/10.1055/s-0033-1360127

Article  CAS  PubMed  Google Scholar 

Al Za’abi M, Ali H, Al Sabahi M, Ali BH (2021) The salutary action of melatonin and betaine, given singly or concomitantly, on cisplatin-induced nephrotoxicity in mice. Naunyn Schmiedebergs Arch Pharmacol 394:1693–1701. https://doi.org/10.1007/s00210-021-02097-z

Article  CAS  PubMed  Google Scholar 

Zhao G, He F, Wu C et al (2018) Betaine in inflammation: mechanistic aspects and applications. Front Immunol 9:1070. https://doi.org/10.3389/fimmu.2018.01070

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng Y, Guo M, Fang X et al (2021) Gut microbiota-derived trimethylamine N-Oxide and kidney function: a systematic review and Meta-analysis. Adv Nutr 12:1286–1304. https://doi.org/10.1093/advances/nmab010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ling C-W, Zhong H, Zeng F-F et al (2024) Cohort Profile: Guangzhou Nutrition and Health Study (GNHS): a Population-based Multi-omics Study. J Epidemiol 34:301–306. https://doi.org/10.2188/jea.JE20230108

Article  PubMed  PubMed Central  Google Scholar 

Chen Y-M, Liu Y, Liu Y-H et al (2015) Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults. Int J Obes (Lond) 39:465–471. https://doi.org/10.1038/ijo.2014.158

Article  CAS  PubMed  Google Scholar 

Zhang Z, Deng J, He L et al (2013) Comparison of various Anthropometric and Body Fat indices in identifying Cardiometabolic disturbances in Chinese men and women. PLoS ONE 8:e70893. https://doi.org/10.1371/journal.pone.0070893

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C-X, Ho SC (2009) Validity and reproducibility of a food frequency questionnaire among Chinese women in Guangdong Province. Asia Pac J Clin Nutr 18:240–250

CAS  PubMed  Google Scholar 

Yuan Y-Q, Li F, Wu H et al (2018) Evaluation of the validity and reliability of the Chinese healthy eating index. Nutrients 10:114. https://doi.org/10.3390/nu10020114

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen P-Y, Fang A-P, Wang X-Y et al (2018) Adherence to the Chinese or American Dietary Guidelines is Associated with a lower risk of primary Liver Cancer in China: a case-control study. Nutrients 10:1113. https://doi.org/10.3390/nu10081113

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ainsworth BE, Haskell WL, Herrmann SD et al (2011) 2011 Compendium of Physical activities: a second update of codes and MET values. Med Sci Sports Exerc 43:1575–1581. https://doi.org/10.1249/MSS.0b013e31821ece12

Article  PubMed