Abrams P, Chapple C, Khoury S, Roehrborn C, de la Rosette J, International Scientific Committee. Evaluation and treatment of lower urinary tract symptoms in older men. J Urol. 2009;181(4):1779–87.

Article  CAS  PubMed  Google Scholar 

Lepor H. Pathophysiology of lower urinary tract symptoms in the aging male population. Rev Urol. 2005;7(Suppl 7):3–11.

Google Scholar 

Langan RC. Benign Prostatic Hyperplasia. Prim Care. 2019;46(2):223–32.

Article  PubMed  Google Scholar 

Prostate Enlargement (Benign Prostatic Hyperplasia.) - NIDDK [Internet]. [cited 2023 Apr 21]. Available from: https://www.niddk.nih.gov/health-information/urologic-diseases/prostate-problems/prostate-enlargement-benign-prostatic-hyperplasia.

Lee AJ, Garraway WM, Simpson RJ, Fisher W, King D. The natural history of untreated lower urinary tract symptoms in middle-aged and elderly men over a period of five years. Eur Urol. 1998;34(4):325–32.

Article  CAS  PubMed  Google Scholar 

Xiong Y, Zhang Y, Li X, Qin F, Yuan J. The prevalence and associated factors of lower urinary tract symptoms suggestive of Benign Prostatic Hyperplasia in aging males. Aging Male. 2020;23(5):1432–9.

Article  PubMed  Google Scholar 

Kassi E, Pervanidou P, Kaltsas G, Chrousos G. Metabolic syndrome: definitions and controversies. BMC Med. 2011;9:48.

Article  PubMed  PubMed Central  Google Scholar 

NCEP ATP-III. Cholesterol Guidelines -- Cholesterol 2.0 - SCYMED [Internet]. [cited 2023 Apr 21]. Available from: http://www.scymed.com/en/smnxdj/edzr/edzr9610.htm.

Nicholson TM, Ricke WA. Androgens and estrogens in Benign Prostatic Hyperplasia: past, present and future. Differentiation. 2011;82(4–5):184–99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiong Y, Zhang Y, Tan J, Qin F, Yuan J. The association between metabolic syndrome and lower urinary tract symptoms suggestive of Benign Prostatic Hyperplasia in aging males: evidence based on propensity score matching. Transl Androl Urol. 2021;10(1):384–96.

Article  PubMed  PubMed Central  Google Scholar 

Lee RK, Chung D, Chughtai B, Te AE, Kaplan SA. Central obesity as measured by waist circumference is predictive of severity of lower urinary tract symptoms. BJU Int. 2012;110(4):540–5.

Article  PubMed  Google Scholar 

Ferreira FT, Daltoé L, Succi G, Cunha F, Ferreira JM, Lorenzetti F, et al. Relation between glycemic levels and low tract urinary symptoms in elderly. Aging Male. 2015;18(1):34–7.

Article  CAS  PubMed  Google Scholar 

Park HK, Lee HW, Lee KS, Byun S-S, Jeong SJ, Hong SK, et al. Relationship between lower urinary tract symptoms and metabolic syndrome in a community-based elderly population. Urology. 2008;72(3):556–60.

Article  PubMed  Google Scholar 

Gupta A, Gupta S, Pavuk M, Roehrborn CG. Anthropometric and metabolic factors and risk of Benign Prostatic Hyperplasia: a prospective cohort study of Air Force veterans. Urology. 2006;68(6):1198–205.

Article  PubMed  Google Scholar 

Ohgaki K, Hikima N, Horiuchi K, Kondo Y. Association between metabolic syndrome and male lower urinary tract symptoms in Japanese subjects using three sets of criteria for metabolic syndrome and international prostate symptom score. Urology. 2011;77(6):1432–8.

Article  PubMed  Google Scholar 

Charan J, Biswas T. How to calculate sample size for different study designs in medical research? Indian J Psychol Med. 2013;35(2):121–6.

Article  PubMed  PubMed Central  Google Scholar 

Calculator. International Prostatism Symptom Score (IPSS) - UpToDate [Internet]. [cited 2023 Apr 21]. Available from: https://www.uptodate.com/contents/calculator-international-prostatism-symptom-score-ipss.

Delavari A, Forouzanfar MH, Alikhani S, Sharifian A, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable Diseases of Iran. Diabetes Care. 2009;32(6):1092–7.

Article  PubMed  PubMed Central  Google Scholar 

Abu Sham’a RAH, Darwazah AK, Kufri FH, Yassin IH, Torok NI. MetS and cardiovascular risk factors among palestinians of East Jerusalem. East Mediterr Health J. 2009;15(6):1464–73.

PubMed  Google Scholar 

Kozan O, Oguz A, Abaci A, Erol C, Ongen Z, Temizhan A, et al. Prevalence of the metabolic syndrome among Turkish adults. Eur J Clin Nutr. 2007;61(4):548–53.

Article  CAS  PubMed  Google Scholar 

Pashootan P, Ploussard G, Cocaul A, de Gouvello A, Desgrandchamps F. Association between metabolic syndrome and severity of lower urinary tract symptoms (LUTS): an observational study in a 4666 European men cohort. BJU Int. 2015;116(1):124–30.

Article  PubMed  Google Scholar 

Ozden C, Ozdal OL, Urgancioglu G, Koyuncu H, Gokkaya S, Memis A. The correlation between metabolic syndrome and prostatic growth in patients with Benign Prostatic Hyperplasia. Eur Urol. 2007;51(1):199–203. discussion 204.

Article  PubMed  Google Scholar 

Hammarsten J, Högstedt B, Holthuis N, Mellström D. Components of the metabolic syndrome-risk factors for the development of Benign Prostatic Hyperplasia. Prostate Cancer Prostatic Dis. 1998;1(3):157–62.

Article  CAS  PubMed  Google Scholar 

Li J, Peng L, Cao D, Gou H, Li Y, Wei Q. The association between metabolic syndrome and Benign Prostatic Hyperplasia: a systematic review and meta-analysis. Aging Male. 2020;23(5):1388–99.

Article  PubMed  Google Scholar 

Fu Y, Zhou Z, Yang B, Zhang K, He L, Zhang X. The relationship between the clinical progression of Benign Prostatic Hyperplasia and metabolic syndrome: a prospective study. Urol Int. 2016;97(3):330–5.

Article  PubMed  Google Scholar 

Liu SY-W, Yee CH, Chiu PK-F, Lam CC-H, Wong SK-H, Ng EK-W, et al. The effect of bariatric Surgery on the improvement of lower urinary tract symptoms in morbidly obese male patients. Prostate Cancer Prostatic Dis. 2021;24(2):380–8.

Article  PubMed  Google Scholar 

Dahle SE, Chokkalingam AP, Gao Y-T, Deng J, Stanczyk FZ, Hsing AW. Body size and serum levels of insulin and leptin in relation to the risk of Benign Prostatic Hyperplasia. J Urol. 2002;168(2):599–604.

Article  CAS  PubMed  Google Scholar 

Vital P, Castro P, Ittmann M. Oxidative stress promotes Benign Prostatic Hyperplasia. Prostate. 2016;76(1):58–67.

Article  CAS  PubMed  Google Scholar 

Nickel JC, Downey J, Young I, Boag S. Asymptomatic inflammation and/or Infection in Benign Prostatic Hyperplasia. BJU Int. 1999;84(9):976–81.

Article  CAS  PubMed  Google Scholar 

Anim JT, Udo C, John B. Characterisation of inflammatory cells in Benign Prostatic Hyperplasia. Acta Histochem. 1998;100(4):439–49.

Article  CAS  PubMed  Google Scholar 

Zhang S-J, Qian H-N, Zhao Y, Sun K, Wang H-Q, Liang G-Q, et al. Relationship between age and prostate size. Asian J Androl. 2013;15(1):116–20.

Article  PubMed  Google Scholar