Ruxton K, Woodman RJ, Mangoni AA. Drugs with anticholinergic effects and cognitive impairment, falls and all-cause mortality in older adults: a systematic review and meta-analysis. Br J Clin Pharmacol. 2015;80:209–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salahudeen MS, Duffull SB, Nishtala PS. Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review. BMC Geriatr. 2015;15:31.

Article  PubMed  PubMed Central  Google Scholar 

Kersten H, Wyller TB. Anticholinergic drug burden in older people’s brain—how well is it measured? Basic Clin Pharmacol Toxicol. 2014;114:151–9.

Article  CAS  PubMed  Google Scholar 

Cardwell K, Hughes CM, Ryan C. The association between anticholinergic medication burden and health related outcomes in the “oldest old”: a systematic review of the literature. Drugs Aging. 2015;32:835–48.

Article  CAS  PubMed  Google Scholar 

Welsh TJ, van der Wardt V, Ojo G, Gordon AL, Gladman JRF. Anticholinergic drug burden tools/scales and adverse outcomes in different clinical settings: a systematic review of reviews. Drugs Aging. 2018;35:523–38.

Article  CAS  PubMed  Google Scholar 

Fox C, Smith T, Maidment I, Chan W-Y, Bua N, Myint PK, et al. Effect of medications with anti-cholinergic properties on cognitive function, delirium, physical function and mortality: a systematic review. Age Ageing. 2014;43:604–15.

Article  PubMed  Google Scholar 

Egberts A, Moreno-Gonzalez R, Alan H, Ziere G, Mattace-Raso FUS. Anticholinergic drug burden and delirium: a systematic review. J Am Med Dir Assoc. 2021;22:65-73.e4.

Article  PubMed  Google Scholar 

Abrams P, Andersson K-E, Buccafusco JJ, Chapple C, de Groat WC, Fryer AD, et al. Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder. Br J Pharmacol. 2006;148:565–78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salahudeen MS, Chyou T-Y, Nishtala PS. Serum anticholinergic activity and cognitive and functional adverse outcomes in older people: a systematic review and meta-analysis of the literature. PLoS ONE. 2016;11: e0151084.

Article  PubMed  PubMed Central  Google Scholar 

Villalba-Moreno AM, Alfaro-Lara ER, Pérez-Guerrero MC, Nieto-Martín MD, Santos-Ramos B. Systematic review on the use of anticholinergic scales in poly pathological patients. Arch Gerontol Geriatr. 2016;62:1–8.

Article  CAS  PubMed  Google Scholar 

Boustani M, Campbell N, Munger S, Maidment I, Fox C. Impact of anticholinergics on the aging brain: a review and practical application. Aging Health. 2008;4:311–20.

Article  CAS  Google Scholar 

Pasina L, Colzani L, Cortesi L, Tettamanti M, Zambon A, Nobili A, et al. Relation between delirium and anticholinergic drug burden in a cohort of hospitalized older patients: an observational study. Drugs Aging. 2019;36:85–91.

Article  CAS  PubMed  Google Scholar 

Pasina L, Lucca U, Tettamanti M. Relation between anticholinergic burden and cognitive impairment: results from the Monzino 80-plus population-based study. Pharmacoepidemiol Drug Saf. 2020;29:1696–702.

Article  CAS  PubMed  Google Scholar 

Michael HU, Enechukwu O, Brouillette M-J, Tamblyn R, Fellows LK, Mayo NE. The prognostic utility of anticholinergic burden scales: an integrative review and gap analysis. Drugs Aging. 2023. https://doi.org/10.1007/s40266-023-01050-4.

Article  PubMed  Google Scholar 

Katzman R, Brown T, Fuld P, Peck A, Schechter R, Schimmel H. Validation of a short Orientation-Memory-Concentration Test of cognitive impairment. Am J Psychiatry. 1983;140:734–9.

Article  CAS  PubMed  Google Scholar 

Ehrt U, Broich K, Larsen JP, Ballard C, Aarsland D. Use of drugs with anticholinergic effect and impact on cognition in Parkinson’s disease: a cohort study. J Neurol Neurosurg Psychiatry. 2010;81:160–5.

Article  PubMed  Google Scholar 

Ancelin ML, Artero S, Portet F, Dupuy A-M, Touchon J, Ritchie K. Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study. BMJ. 2006;332:455–9.

Article  PubMed  PubMed Central  Google Scholar 

Rube T, Ecorcheville A, Londos E, Modig S, Johansson P. Development of the Swedish anticholinergic burden scale (Swe-ABS). BMC Geriatr. 2023;23:518.

Article  PubMed  PubMed Central  Google Scholar 

Sittironnarit G, Ames D, Bush AI, Faux N, Flicker L, Foster J, et al. Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study. Dement Geriatr Cogn Disord. 2011;31:173–8.

Article  CAS  PubMed  Google Scholar 

Carnahan RM, Lund BC, Perry PJ, Pollock BG, Culp KR. The anticholinergic drug scale as a measure of drug-related anticholinergic burden: associations with serum anticholinergic activity. J Clin Pharm. 2006;46:1481–6.

Article  CAS  Google Scholar 

Bishara D, Harwood D, Sauer J, Taylor DM. Anticholinergic effect on cognition (AEC) of drugs commonly used in older people. Int J Geriatr Psychiatry. 2017;32:650–6.

Article  PubMed  Google Scholar 

Briet J, Javelot H, Heitzmann E, Weiner L, Lameira C, D’Athis P, et al. The anticholinergic impregnation scale: towards the elaboration of a scale adapted to prescriptions in French psychiatric settings. Therapie. 2017;72:427–37.

Article  PubMed  Google Scholar 

Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The anticholinergic risk scale and anticholinergic adverse effects in older persons. Arch Intern Med. 2008;168:508–13.

Article  PubMed  Google Scholar 

Rt N, Amm R. Development of a Brazilian anticholinergic activity drug scale. Einstein (Sao Paulo, Brazil) [Internet]. 2019 [cited 2023 Mar 2];17. Available from: https://pubmed.ncbi.nlm.nih.gov/30942279/.

Cancelli I, Valentinis L, Merlino G, Valente M, Gigli GL. Drugs with anticholinergic properties as a risk factor for psychosis in patients affected by Alzheimer’s disease. Clin Pharmacol Ther. 2008;84:63–8.

Article  CAS  PubMed  Google Scholar 

Ramos H, Moreno L, Pérez-Tur J, Cháfer-Pericás C, García-Lluch G, Pardo J. CRIDECO Anticholinergic Load Scale: an updated anticholinergic burden scale. Comparison with the ACB scale in Spanish individuals with subjective memory complaints. J Pers Med. 2022;12:207.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chew ML, Mulsant BH, Pollock BG, Lehman ME, Greenspan A, Mahmoud RA, et al. Anticholinergic activity of 107 medications commonly used by older adults. J Am Geriatr Soc. 2008;56:1333–41.

Article  PubMed  Google Scholar 

Han L, McCusker J, Cole M, Abrahamowicz M, Primeau F, Elie M. Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. Arch Intern Med. 2001;161:1099–105.

Article  CAS  PubMed  Google Scholar 

Hefner G, Shams M, K W-S. Rating the delirogenic potential of drugs for prediction of side effects in elderly psychiatric inpatients. J Pharm Pharmacovigil. 2015;1(003).

Kiesel EK, Hopf YM, Drey M. An anticholinergic burden score for German prescribers: score development. BMC Geriatr. 2018;18:239.

Article  PubMed  PubMed Central  Google Scholar 

Jun K, Hwang S, Ah Y-M, Suh Y, Lee J-Y. Development of an Anticholinergic Burden Scale specific for Korean older adults. Geriatr Gerontol Int. 2019;19:628–34.

Article  PubMed  Google Scholar 

Kable A, Fullerton A, Fraser S, Palazzi K, Hullick C, Oldmeadow C, et al. Comparison of potentially inappropriate medications for people with dementia at admission and discharge during an unplanned admission to hospital: results from the SMS dementia study. Healthcare. 2019;7:8.

Article  PubMed  PubMed Central  Google Scholar 

Joshi YB, Thomas ML, Braff DL, Green MF, Gur RC, Gur RE, et al. Anticholinergic medication burden-associated cognitive impairment in schizophrenia. Am J Psychiatry. 2021;178:838–47.

Article