Centers for Disease Control and Prevention. National diabetes statistics report 2022. https://www.cdc.gov/diabetes/php/data-research/index.html. Accessed Feb 25, 2025.
American Diabetes Association. Economic costs of diabetes in the U.S. in 2017. Diabetes Care. 2018;41:917–28.
Article PubMed Central Google Scholar
Rowley WR, Bezold C, Arikan Y, Byrne E, Krohe S. Diabetes 2030: insights from yesterday, today, and future trends. Popul Health Manag. 2017;20:6–12.
Article PubMed PubMed Central Google Scholar
American Diabetes Association. Standards of care in diabetes—2023. Diabetes Care. 2023;46:S1–291.
ElSayed NA, Aleppo G, Aroda VR, et al. Pharmacologic approaches to glycemic treatment: standards of care in diabetes-2023. Diabetes Care. 2023;46:S140–57.
Article CAS PubMed Google Scholar
American Diabetes Association Professional Practice Committee. Pharmacologic approaches to glycemic treatment: standards of care in diabetes-2025. Diabetes Care. 2025;48:S181–206.
Buse JB, Wexler DJ, Tsapas A, et al. 2019 update to: management of hyperglycemia in type 2 diabetes, 2018—a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2020;43:487–93.
Article CAS PubMed Google Scholar
Davies MJ, D’Alessio DA, Fradkin J, et al. Management of hyperglycemia in type 2 diabetes, 2018: a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018;41:2669–701.
Article PubMed PubMed Central Google Scholar
Garber AJ, Abrahamson MJ, Barzilay JI, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm: 2019 executive summary. Endocr Pract. 2019;25:69–100.
Almandoz JP, Lingvay I, Morales J, Campos C. Switching between glucagon-like peptide-1 receptor agonists: rationale and practical guidance. Clin Diabetes. 2020;38:390–402.
Article PubMed PubMed Central Google Scholar
Divino V, Boye KS, Lebrec J, DeKoven M, Norrbacka K. GLP-1 RA treatment and dosing patterns among type 2 diabetes patients in six countries: a retrospective analysis of pharmacy claims data. Diabetes Ther. 2019;10:1067–88.
Article CAS PubMed PubMed Central Google Scholar
Divino V, DeKoven M, Khan FA, Boye KS, Sapin H, Norrbacka K. GLP-1 RA treatment patterns among type 2 diabetes patients in five European countries. Diabetes Ther. 2017;8:115–28.
Article CAS PubMed PubMed Central Google Scholar
Weiss T, Carr RD, Pal S, et al. Real-world adherence and discontinuation of glucagon-like peptide-1 receptor agonists therapy in type 2 diabetes mellitus patients in the United States. Patient Prefer Adherence. 2020;14:2337–45.
Article PubMed PubMed Central Google Scholar
Capehorn MS, Catarig AM, Furberg JK, et al. Efficacy and safety of once-weekly semaglutide 1.0 mg vs once-daily liraglutide 1.2 mg as add-on to 1–3 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 10). Diabetes Metab. 2020;46:100–9.
Article CAS PubMed Google Scholar
Alsugair HA, Alshugair IF, Alharbi TJ, Bin Rsheed AM, Tourkmani AM, Al-Madani W. Weekly semaglutide vs liraglutide efficacy profile: a network meta-analysis. Healthcare (Basel). 2021;9:1125.
Jain AB, Kanters S, Khurana R, Kissock J, Severin N, Stafford SG. Real-world effectiveness analysis of switching from liraglutide or dulaglutide to semaglutide in patients with type 2 diabetes mellitus: the retrospective REALISE-DM study. Diabetes Ther. 2021;12:527–36.
Article CAS PubMed Google Scholar
Kassem S, Khalaila B, Stein N, Saliba W, Zaina A. Efficacy, adherence and persistence of various glucagon-like peptide-1 agonists: nationwide real-life data. Diabetes Obes Metab. 2024;26:4646–52.
Article CAS PubMed Google Scholar
Marso SP, Bain SC, Consoli A, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375:1834–44.
Article CAS PubMed Google Scholar
Newsome P, Sanyal A, Kliers I, et al. Phase 3 ESSENCE trial: semaglutide in metabolic dysfunction associated steatohepatitis (MASH). The Liver Meeting; November 15–19, 2024; San Diego, CA. (AASLD abstract 5018), 2024.
Perkovic V, Tuttle KR, Rossing P, et al. Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes. N Engl J Med. 2024;391:109–21.
Article CAS PubMed Google Scholar
Buysman EK, Liu F, Hammer M, Langer J. Impact of medication adherence and persistence on clinical and economic outcomes in patients with type 2 diabetes treated with liraglutide: a retrospective cohort study. Adv Ther. 2015;32:341–55.
Article CAS PubMed PubMed Central Google Scholar
Melzer-Cohen C, Chodick G, Husemoen LLN, Rhee N, Shalev V, Karasik A. A retrospective database study of liraglutide persistence associated with glycemic and body weight control in patients with type 2 diabetes. Diabetes Ther. 2019;10:683–96.
Article CAS PubMed PubMed Central Google Scholar
Uzoigwe C, Noone J, Liang Y, Ali SN, Gamble C. Increased healthcare resource use and costs after discontinuation of liraglutide in patients with type 2 diabetes from a commercial- and Medicaid-insured claims database. Diabetes Ther. 2022;13:1861–74.
Article CAS PubMed PubMed Central Google Scholar
Buysman EK, Sikirica MV, Thayer SW, Bogart M, DuCharme MC, Joshi AV. Real-world comparison of treatment patterns and effectiveness of albiglutide and liraglutide. J Comp Eff Res. 2018;7:89–100.
Crabtree TSJ, Adamson K, Reid H, et al. Injectable semaglutide and reductions in HbA1c and weight in the real world in people switched from alternative glucagon-like peptide-1 receptor agonists. Diabetes Obes Metab. 2022;24:1398–401.
Article CAS PubMed PubMed Central Google Scholar
Lingvay I, Kirk AR, Lophaven S, Wolden ML, Shubrook JH. Outcomes in GLP-1 RA-experienced patients switching to once-weekly semaglutide in a real-world setting: the retrospective, observational EXPERT study. Diabetes Ther. 2021;12:879–96.
Article CAS PubMed PubMed Central Google Scholar
Goncalves E, Bell DS. Efficacy of semaglutide versus liraglutide in clinical practice. Diabetes Metab. 2020;46:515–7.
Article CAS PubMed Google Scholar
Evans M, Berry S, Malkin SJP, Hunt B, Sharma A. Evaluating the long-term cost-effectiveness of once-weekly semaglutide 1 mg versus liraglutide 1.8 mg: a health economic analysis in the UK. Diabetes Ther. 2023;14:1005–21.
Article CAS PubMed PubMed Central Google Scholar
Jain AB, Ali A, Gorgojo Martínez JJ, et al. Switching between GLP-1 receptor agonists in clinical practice: expert consensus and practical guidance. Int J Clin Pract. 2021;75:e13731.
American Diabetes Association Professional Practice Committee. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2020. Diabetes Care. 2020;43:S98-110.
Beyrer J, Manjelievskaia J, Bonafede M, et al. Validation of an international classification of disease, 10th revision coding adaptation for the Charlson comorbidity index in United States healthcare claims data. Pharmacoepidemiol Drug Saf. 2021;30:582–93.
Article PubMed PubMed Central Google Scholar
Glasheen WP, Renda A, Dong Y. Diabetes complications severity index (DCSI)-update and ICD-10 translation. J Diabetes Complicat. 2017;31:1007–13.
Xu S, Ross C, Raebel MA, Shetterly S, Blanchette C, Smith D. Use of stabilized inverse propensity scores as weights to directly estimate relative risk and its confidence intervals. Value Health. 2010;13:273–7.
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