Fricke J, Ávila G, Keller T, Weller K, Lau S, Maurer M, et al. Prevalence of chronic urticaria in children and adults across the Globe: systematic review with meta-analysis. Allergy. 2020;75:423–32.
Gonçalo M, Gimenéz-Arnau A, Al-Ahmad M, Ben-Shoshan M, Bernstein JA, Ensina LF, et al. The global burden of chronic urticaria for the patient and society. Br J Dermatol. 2021;184:226–36.
Kocatürk E, Grattan C. Is chronic urticaria more than skin deep? Clin Transl Allergy. 2019;9:48.
Article PubMed PubMed Central Google Scholar
He L, Yi W, Huang X, Long H, Lu Q. Chronic urticaria: advances in Understanding of the disease and clinical management. Clin Rev Allergy Immunol. 2021;61:424–48.
Baudy A, Raison-Peyron N, Serrand C, Crépy M-N, Du-Thanh A. Impact of chronic spontaneous or inducible urticaria on occupational activity. Acta Derm Venereol. 2024;104:adv36122.
Zuberbier T, Abdul Latiff AH, Abuzakouk M, Aquilina S, Asero R, Baker D, et al. The international EAACI/GA2LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy. 2022;77:734–66.
Hon KL, Leung AKC, Ng WGG, Loo SK. Chronic urticaria: an overview of treatment and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2019;13:27–37.
Article CAS PubMed PubMed Central Google Scholar
Kolkhir P, Giménez-Arnau AM, Kulthanan K, Peter J, Metz M, Maurer M, Urticaria. Nat Rev Dis Primers. 2022;8:61.
Szymanski K, Schaefer P. Urticaria and angioedema. Prim Care. 2023;50:237–52.
Church MK, Kolkhir P, Metz M, Maurer M. The role and relevance of mast cells in urticaria. Immunol Rev. 2018;282:232–47.
Article CAS PubMed Google Scholar
Schaefer P. Acute and chronic urticaria: evaluation and treatment. Am Fam Physician. 2017;95:717–24.
Iriarte Sotés P, Armisén M, Usero-Bárcena T, Rodriguez Fernández A, Otero Rivas MM, Gonzalez MT, et al. Efficacy and safety of Up-dosing antihistamines in chronic spontaneous urticaria: A systematic review of the literature. J Investig Allergol Clin Immunol. 2021;31:282–91.
Giménez-Arnau AM, Manzanares N, Podder I. Recent updates in urticaria. Med Clin (Barc). 2023;161:435–44.
Altrichter S, Staubach P, Pasha M, Singh B, Chang AT, Bernstein JA, et al. An open-label, proof-of-concept study of lirentelimab for antihistamine-resistant chronic spontaneous and inducible urticaria. J Allergy Clin Immunol. 2022;149:1683–e16907.
Article CAS PubMed Google Scholar
Wedi B. Emerging treatments for chronic urticaria. Expert Opin Investig Drugs. 2022;31:281–90.
Article CAS PubMed Google Scholar
Jafferany M, Franca K, Psychodermatology. Basics concepts. Acta Derm Venereol. 2016;96:35–7.
Gieler U, Gieler T, Peters EMJ, Linder D. Skin and Psychosomatics - Psychodermatology today. J Dtsch Dermatol Ges. 2020;18:1280–98.
PubMed PubMed Central Google Scholar
Konstantinou GN, Konstantinou GN. Psychiatric comorbidity in chronic urticaria patients: a systematic review and meta-analysis. Clin Transl Allergy. 2019;9:42.
Article PubMed PubMed Central Google Scholar
Staubach P, Dechene M, Metz M, Magerl M, Siebenhaar F, Weller K, et al. High prevalence of mental disorders and emotional distress in patients with chronic spontaneous urticaria. Acta Derm Venereol. 2011;91:557–61.
Bangera A, Singh M, Godse K, Patil S. The incidence of depression and anxiety disorders in spontaneous chronic urticaria patients. Qatar Med J. 2023;2023:16.
PubMed PubMed Central Google Scholar
Dortas Junior SD, Azizi GG, Moret RN, Bastos Junior RM, Valle SOR. Spiritual well-being and quality of life are impaired in chronic urticaria. Eur Ann Allergy Clin Immunol. 2021;53:221–7.
Article CAS PubMed Google Scholar
Pyatilova P, Hackler Y, Aulenbacher F, Asero R, Bauer A, Bizjak M, et al. Non-Skin related symptoms are common in chronic spontaneous urticaria and linked to active and uncontrolled disease: results from the chronic urticaria registry. J Allergy Clin Immunol Pract. 2024;12:1890–e18993.
Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, et al. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled receptors drives Non-histaminergic itch. Immunity. 2019;50:1163–e11715.
Article CAS PubMed PubMed Central Google Scholar
Asero R, Marzano AV, Ferrucci S, Lorini M, Carbonelli V, Cugno M. Co-occurrence of IgE and IgG autoantibodies in patients with chronic spontaneous urticaria. Clin Exp Immunol. 2020;200:242–9.
Article CAS PubMed PubMed Central Google Scholar
Kühn H, Kolkhir P, Babina M, Düll M, Frischbutter S, Fok JS, et al. Mas-related G protein-coupled receptor X2 and its activators in dermatologic allergies. J Allergy Clin Immunol. 2021;147:456–69.
Lerner L, Babina M, Zuberbier T, Stevanovic K. Beyond Allergies-Updates on the role of Mas-Related G-Protein-Coupled receptor X2 in chronic urticaria and atopic dermatitis. Cells. 2024;13:220.
Article CAS PubMed PubMed Central Google Scholar
Elieh-Ali-Komi D, Metz M, Kolkhir P, Kocatürk E, Scheffel J, Frischbutter S, et al. Chronic urticaria and the pathogenic role of mast cells. Allergol Int. 2023;72:359–68.
Article CAS PubMed Google Scholar
Larenas-Linnemann D. Biomarkers of autoimmune chronic spontaneous urticaria. Curr Allergy Asthma Rep. 2023;23:655–64.
Article CAS PubMed Google Scholar
Zhou B, Li J, Liu R, Zhu L, Peng C. The role of crosstalk of immune cells in pathogenesis of chronic spontaneous urticaria. Front Immunol. 2022;13:879754.
Article CAS PubMed PubMed Central Google Scholar
Matsubara D, Yanase Y, Ishii K, Takahagi S, Tanaka A, Ozawa K, et al. Basophils activation of patients with chronic spontaneous urticaria in response to C5a despite failure to respond to IgE-mediated stimuli. Front Immunol. 2022;13:994823.
Article CAS PubMed PubMed Central Google Scholar
Mostmans Y, De Smedt K, Feoli F, Waelput W, De Maertelaer V, Olemans C, et al. Elevated cutaneous expression of stem cell factor in chronic spontaneous urticaria: a prospective cohort study. Clin Exp Dermatol. 2024;49:1659–67.
Yanase Y, Takahagi S, Ozawa K, Hide M. The role of coagulation and complement factors for mast cell activation in the pathogenesis of chronic spontaneous urticaria. Cells. 2021;10:1759.
Article CAS PubMed PubMed Central Google Scholar
Asero R. Mechanisms of Histamine release from mast cells beyond the high affinity IgE receptor in severe chronic spontaneous urticaria. Immunol Lett. 2024;265:1–4.
Article CAS PubMed Google Scholar
Carvalho RFda, Nilsson S, Harvima G. Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation. Exp Dermatol. 2010;19:117–22.
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