Longhi MS, Moss A, Jiang ZG, Robson SC (2017) Purinergic signaling during intestinal inflammation. J Mol Med (Berl) 95:915–925. https://doi.org/10.1007/s00109-017-1545-1
Article CAS PubMed Google Scholar
King BF (2015) Purinergic signalling in the enteric nervous system (An overview of current perspectives). Autonomic Neurosci : basic & clinical 191:141–147. https://doi.org/10.1016/j.autneu.2015.05.005
Burnstock G (2014) Purinergic signalling in the gastrointestinal tract and related organs in health and disease. Purinergic Signal 10:3–50. https://doi.org/10.1007/s11302-013-9397-9
Article CAS PubMed Google Scholar
Galligan JJ, Bertrand PP (1994) ATP mediates fast synaptic potentials in enteric neurons. J Neurosci : Off J Soc Neurosci 14:7563–7571
Bertrand PP, Bornstein JC (2002) ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors. J Neurosci 22:4767–4775. https://doi.org/10.1523/jneurosci.22-12-04767.2002
Article CAS PubMed PubMed Central Google Scholar
Bornstein JC, Hendriks R, Furness JB, Trussell DC (1999) Ramifications of the axons of AH-neurons injected with the intracellular marker biocytin in the myenteric plexus of the guinea pig small intestine. J Comp Neurol 314:437–451. https://doi.org/10.1002/cne.903140303
LePard K, Messori E, Galligan J (1997) Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: Distribution and pharmacology. Gastroenterology 113:1522–1534. https://doi.org/10.1053/gast.1997.v113.pm9352854
Article CAS PubMed Google Scholar
Xiang Z, Burnstock G (2005) Distribution of P2Y2 receptors in the guinea pig enteric nervous system and its coexistence with P2X2 and P2X3 receptors, neuropeptide Y, nitric oxide synthase and calretinin. Histochem Cell Biol 124:379–390. https://doi.org/10.1007/s00418-005-0043-7
Article CAS PubMed Google Scholar
Xiang Z, Burnstock G (2006) Distribution of P2Y6 and P2Y12 receptor: their colocalization with calbindin, calretinin and nitric oxide synthase in the guinea pig enteric nervous system. Histochem Cell Biol 125:327–336. https://doi.org/10.1007/s00418-005-0071-3
Article CAS PubMed Google Scholar
Hu H-Z, Gao N, Zhu MX et al (2003) Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous system. J Physiol 550:493–504. https://doi.org/10.1113/jphysiol.2003.041731
Article CAS PubMed PubMed Central Google Scholar
Gao N, Hu H, Zhu MX et al (2006) The P2Y1 purinergic receptor expressed by enteric neurones in guinea-pig intestine. Neurogastroenterol Motil 18:316–323. https://doi.org/10.1111/j.1365-2982.2005.00754.x
Article CAS PubMed Google Scholar
Hwang SJ, Blair PJ, Durnin L et al (2012) P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit. J Physiology 590:1957–1972. https://doi.org/10.1113/jphysiol.2011.224634
Kurahashi M, Mutafova-Yambolieva V, Koh SD, Sanders KM (2014) Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles. Am J Physiol Cell Physiol 307:C561–C570. https://doi.org/10.1152/ajpcell.00080.2014
Article CAS PubMed PubMed Central Google Scholar
Baker SA, Hennig GW, Ward SM, Sanders KM (2015) Temporal sequence of activation of cells involved in purinergic neurotransmission in the colon. J Physiol 593:1945–1963. https://doi.org/10.1113/jphysiol.2014.287599
Article CAS PubMed PubMed Central Google Scholar
Lavoie EG, Gulbransen BD, Martín-Satué M et al (2011) Ectonucleotidases in the digestive system: focus on NTPDase3 localization. Am J Physiol-gastr L 300:G608–G620. https://doi.org/10.1152/ajpgi.00207.2010
Grubišić V, Perez-Medina AL, Fried DE et al (2019) NTPDase1 and -2 are expressed by distinct cellular compartments in the mouse colon and differentially impact colonic physiology and function after DSS colitis. Am J Physiol-gastr L 317:G314–G332. https://doi.org/10.1152/ajpgi.00104.2019
Gulbransen BD, Bashashati M, Hirota SA et al (2012) Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis. Nat Med 18:600–604. https://doi.org/10.1038/nm.2679
Article CAS PubMed PubMed Central Google Scholar
Brown IAM, McClain JL, Watson RE et al (2016) Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide. Cmgh Cell Mol Gastroenterol Hepatol 2:77–91. https://doi.org/10.1016/j.jcmgh.2015.08.007
Scott BM, Gutiérrez-Vázquez C, Sanmarco LM et al (2021) Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease. Nat Med 27:1212–1222. https://doi.org/10.1038/s41591-021-01390-x
Article CAS PubMed Google Scholar
Kimball BC, Mulholland MW (1996) Enteric glia exhibit P2U receptors that increase cytosolic calcium by a phospholipase C-Dependent mechanism. J Neurochem 66:604–612. https://doi.org/10.1046/j.1471-4159.1996.66020604.x
Article CAS PubMed Google Scholar
Gulbransen BD, Sharkey KA (2009) Purinergic neuron-to-glia signaling in the enteric nervous system. Gastroenterology 136:1349–1358. https://doi.org/10.1053/j.gastro.2008.12.058
Article CAS PubMed Google Scholar
Gomes P, Chevalier J, Boesmans W et al (2009) ATP-dependent paracrine communication between enteric neurons and glia in a primary cell culture derived from embryonic mice. Neurogastroenterol Motil 21:870-e62. https://doi.org/10.1111/j.1365-2982.2009.01302.x
Article CAS PubMed Google Scholar
Ahmadzai MM, Seguella L, Gulbransen BD (2021) Circuit-specific enteric glia regulate intestinal motor neurocircuits. Proc Natl Acad Sci 118:e2025938118. https://doi.org/10.1073/pnas.2025938118
Article CAS PubMed PubMed Central Google Scholar
Zeisel A, Hochgerner H, Lönnerberg P et al (2018) Molecular architecture of the mouse nervous system. Cell 174:999-1014.e22. https://doi.org/10.1016/j.cell.2018.06.021
Article CAS PubMed PubMed Central Google Scholar
May-Zhang AA, Tycksen E, Southard-Smith AN et al (2020) Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes In Situ. Gastroenterology. https://doi.org/10.1053/j.gastro.2020.09.032
Drokhlyansky E, Smillie CS, Wittenberghe NV et al (2020) The human and mouse enteric nervous system at single-cell resolution. Cell 182:1606-1622.e23. https://doi.org/10.1016/j.cell.2020.08.003
Article CAS PubMed PubMed Central Google Scholar
von Kügelgen I, Hoffmann K (2016) Pharmacology and structure of P2Y receptors. Neuropharmacology 104:50–61. https://doi.org/10.1016/j.neuropharm.2015.10.030
Jin J, Kunapuli SP (1998) Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. Proc Natl Acad Sci 95:8070–8074. https://doi.org/10.1073/pnas.95.14.8070
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