Armstrong TS, Grant R, Gilbert MR, Lee JW, Norden AD (2016) Epilepsy in glioma patients: mechanisms, management, and impact of anticonvulsant therapy: table 1. Neuro Oncol 18:779–789. https://doi.org/10.1093/neuonc/nov269

Article  CAS  PubMed  Google Scholar 

Balducci L, Colloca G, Cesari M, Gambassi G (2010) Assessment and treatment of elderly patients with cancer. Surg Oncol 19:117–123. https://doi.org/10.1016/j.suronc.2009.11.008

Article  PubMed  Google Scholar 

Bauchet L, Zouaoui S, Darlix A, Menjot de Champfleur N, Ferreira E, Fabbro M, Kerr C, Taillandier L (2014) Assessment and treatment relevance in elderly glioblastoma patients. Neuro Oncol 16:1459–1468. https://doi.org/10.1093/neuonc/nou063

Article  CAS  PubMed  PubMed Central  Google Scholar 

Borger V, Hamed M, Ilic I, Potthoff A-L, Racz A, Schäfer N, Güresir E, Surges R, Herrlinger U, Vatter H, Schneider M, Schuss P (2021) Seizure outcome in temporal glioblastoma surgery: lobectomy as a supratotal resection regime outclasses conventional gross-total resection. J Neurooncol 152:339–346. https://doi.org/10.1007/s11060-021-03705-x

Article  PubMed  PubMed Central  Google Scholar 

Climans SA, Brandes AA, Cairncross JG, Ding K, Fay M, Laperriere N, Menten J, Nishikawa R, O’Callaghan CJ, Perry JR, Phillips C, Roa W, Wick W, Winch C, Mason WP (2020) Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients. J Neurooncol 149:65–71. https://doi.org/10.1007/s11060-020-03573-x

Article  CAS  PubMed  Google Scholar 

Durnford AJ, Rodgers W, Kirkham FJ, Mullee MA, Whitney A, Prevett M, Kinton L, Harris M, Gray WP (2011) Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients. Seizure 20:809–812. https://doi.org/10.1016/j.seizure.2011.08.004

Article  PubMed  Google Scholar 

Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM (2017) Operational classification of seizure types by the international league against epilepsy: position paper of the ILAE commission for classification and terminology. Epilepsia 58:522–530. https://doi.org/10.1111/epi.13670

Article  PubMed  Google Scholar 

Fried LP, Hall WJ (2008) Editorial: leading on behalf of an aging society. J Am Geriatr Soc 56:1791–1795. https://doi.org/10.1111/j.1532-5415.2008.01939.x

Article  PubMed  Google Scholar 

Hanna C, Lawrie TA, Rogozińska E, Kernohan A, Jefferies S, Bulbeck H, Ali UM, Robinson T, Grant R (2020) Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis. Cochrane Database Syst Rev 2020. https://doi.org/10.1002/14651858.CD013261.pub2

Henriksson R, Asklund T, Poulsen HS (2011) Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review. J Neurooncol 104:639–646. https://doi.org/10.1007/s11060-011-0565-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ius T, Pauletto G, Tomasino B, Maieron M, Budai R, Isola M, Cesselli D, Lettieri C, Skrap M (2020) Predictors of postoperative seizure outcome in low grade glioma: from volumetric analysis to molecular stratification. Cancers (Basel) 12:397. https://doi.org/10.3390/cancers12020397

Article  PubMed  Google Scholar 

Jo J, Nevel K, Sutyla R, Smolkin M, Lopes MB, Schiff D (2021) Predictors of early, recurrent, and intractable seizures in low-grade glioma. Neurooncol Pract 8:40–47. https://doi.org/10.1093/nop/npaa054

Article  PubMed  Google Scholar 

Klingenschmid J, Krigers A, Kerschbaumer J, Thomé C, Pinggera D, Freyschlag CF (2022) Surgical management of malignant glioma in the elderly. Front Oncol 12. https://doi.org/10.3389/fonc.2022.900382

Krigers A, Klingenschmid J, Cosar T, Moser P, Thomé C, Freyschlag CF (2022) Age-dependent impact of concomitant radio-chemotherapy and MGMT promotor methylation on PFS and OS in patients with IDH wild-type glioblastoma: the real-life data. Cancers (Basel) 14:6180. https://doi.org/10.3390/cancers14246180

Article  CAS  PubMed  Google Scholar 

Laperriere N, Weller M, Stupp R, Perry JR, Brandes AA, Wick W, van den Bent MJ (2013) Optimal management of elderly patients with glioblastoma. Cancer Treat Rev 39:350–357. https://doi.org/10.1016/j.ctrv.2012.05.008

Article  PubMed  Google Scholar 

Lorimer CF, Saran F, Chalmers AJ, Brock J (2016) Glioblastoma in the elderly - how do we choose who to treat? J Geriatr Oncol 7:453–456. https://doi.org/10.1016/j.jgo.2016.07.005

Article  PubMed  Google Scholar 

Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97–109. https://doi.org/10.1007/s00401-007-0243-4

Article  PubMed  PubMed Central  Google Scholar 

Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131:803–820. https://doi.org/10.1007/s00401-016-1545-1

Article  PubMed  Google Scholar 

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23:1231–1251. https://doi.org/10.1093/neuonc/noab106

Article  CAS  PubMed  PubMed Central  Google Scholar 

Minniti G, Lombardi G, Paolini S (2019) Glioblastoma in elderly patients: current management and future perspectives. Cancers (Basel) 11:336. https://doi.org/10.3390/cancers11030336

Article  CAS  PubMed  Google Scholar 

Mor V, Laliberte L, Morris JN, Wiemann M (1984) The karnofsky performance status scale. An examination of its reliability and validity in a research setting. Cancer 53:2002–2007. https://doi.org/10.1002/1097-0142(19840501)53:9<2002::aid-cncr2820530933>3.0.co;2-w

Article  CAS  PubMed  Google Scholar 

Ostrom QT, Price M, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS (2022) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2015–2019. Neuro Oncol 24:v1–v95. https://doi.org/10.1093/neuonc/noac202

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pallud J, Audureau E, Blonski M, Sanai N, Bauchet L, Fontaine D, Mandonnet E, Dezamis E, Psimaras D, Guyotat J, Peruzzi P, Page P, Gal B, Párraga E, Baron M-H, Vlaicu M, Guillevin R, Devaux B, Duffau H, Taillandier L, Capelle L, Huberfeld G (2014) Epileptic seizures in diffuse low-grade gliomas in adults. Brain 137:449–462. https://doi.org/10.1093/brain/awt345

Article  PubMed  Google Scholar 

Pallud J, Roux A, Moiraghi A, Aboubakr O, Elia A, Guinard E, Oppenheim C, Tauziede-Espariat A, Parraga E, Gavaret M, Chrètien F, Huberfeld G, Zanello M (2024) Characteristics and prognosis of tumor-related epilepsy during tumor evolution in patients with IDH wild-type glioblastoma. Neurology 102:e207902. https://doi.org/10.1212/WNL.0000000000207902

Article  CAS  PubMed  Google Scholar 

Rilinger RG, Guo L, Sharma A, Volovetz J, Thompson NR, Grabowski M, Lobbous M, Dhawan A (2024) Tumor-related epilepsy in high-grade glioma: a large series survival analysis. J Neurooncol. https://doi.org/10.1007/s11060-024-04787-z

Article  PubMed  PubMed Central  Google Scholar 

Rilinger RG, Guo L, Sharma A, Volovetz J, Thompson NR, Grabowski M, Lobbous M, Dhawan A (2024) Tumor-related epilepsy in high-grade glioma: a large series survival analysis. J Neurooncol 170:153–160. https://doi.org/10.1007/s11060-024-04787-z

Article  PubMed  PubMed Central  Google Scholar 

Roberts M, Northmore T, Shires J, Taylor P, Hayhurst C (2018) Diffuse low grade glioma after the 2016 WHO update, seizure characteristics, imaging correlates and outcomes. Clin Neurol Neurosurg 175:9–15. https://doi.org/10.1016/j.clineuro.2018.10.001

Article  PubMed  Google Scholar 

Rossi J, Cavallieri F, Bassi MC, Venturelli F, Toschi G, Di Rauso G, Lucchi C, Donati B, Rizzi R, Russo M, Bondavalli M, Iaccarino C, Pavesi G, Neri A, Biagini G, Ciarrocchi A, Rossi PG, Pisanello A, Valzania F (2024) To be or not to be: the dilemma over the prognostic role of epilepsy at presentation in patients with glioblastoma – a systematic review and meta-analysis. BMC Cancer 24:1488. https://doi.org/10.1186/s12885-024-13249-8

Article  PubMed  PubMed Central  Google Scholar