Aadam AA, Abe S. Endoscopic submucosal dissection for superficial esophageal cancer. Dis Esophagus. 2018;31:1–9.

Article  Google Scholar 

Kodama M, Kakegawa T. Treatment of superficial cancer of the esophagus: a summary of responses to a questionnaire on superficial cancer of the esophagus in Japan. Surgery. 1998;123:432–9.

Article  CAS  PubMed  Google Scholar 

Igaki H, Kato H, Tachimori Y, Daiko H, Fukaya M, Yajima S, et al. Clinicopathologic characteristics and survival of patients with clinical Stage I squamous cell carcinomas of the thoracic esophagus treated with three-field lymph node dissection. Eur J Cardiothorac Surg. 2001;20:1089–94.

Article  CAS  PubMed  Google Scholar 

Song SY, Choi W, Shin SS, Lee SW, Do Ahn S, Kim JH, et al. Fractionated stereotactic body radiation therapy for medically inoperable stage I lung cancer adjacent to central large bronchus. Lung Cancer. 2009;66:89–93.

Article  PubMed  Google Scholar 

Kawaguchi G, Sasamoto R, Abe E, Ohta A, Sato H, Tanaka K, et al. The effectiveness of endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer. Radiat Oncol. 2015;10:1–7.

Article  CAS  Google Scholar 

Mochizuki Y, Saito Y, Tsujikawa T, Fujiyama Y, Andoh A. Combination of endoscopic submucosal dissection and chemoradiation therapy for superficial esophageal squamous cell carcinoma with submucosal invasion. Exp Ther Med. 2011;2:1065–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Minashi K, Nihei K, Mizusawa J, Takizawa K, Yano T, Ezoe Y, et al. Efficacy of endoscopic resection and selective chemoradiotherapy for stage I esophageal squamous cell carcinoma. Gastroenterology. 2019;157:382–90.

Article  PubMed  Google Scholar 

Nihei K, Minashi K, Yano T, Shimoda T, Fukuda H, Muto M, et al. Final analysis of diagnostic endoscopic resection followed by selective chemoradiotherapy for stage I esophageal cancer: JCOG0508. Gastroenterology. 2022;164:296–9.

Article  PubMed  Google Scholar 

Li R, Yang Z, Shao F, Cheng H, Wen Y, Sun S, et al. Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes. Nat Commun. 2021;12:1–15.

Google Scholar 

Yanai Y, Hayashi T, Tsuyama S, Nasu M, Hashimoto T, Kajiyama Y, et al. Clinicopathological and mutational analysis of esophageal basaloid squamous cell carcinoma. Virchows Arch. 2022;481:477–87.

Article  CAS  PubMed  Google Scholar 

Kitagawa Y, Uno T, Oyama T, Kato K, Kato H, Kawakubo H, et al. Esophageal cancer practice guidelines 2017 edited by the Japan Esophageal Society: part 1. Esophagus. 2019;16:1–24.

Article  PubMed  Google Scholar 

Wang Y, Zhu L, Xia W, Wang F. Anatomy of lymphatic drainage of the esophagus and lymph node metastasis of thoracic esophageal cancer. Cancer Manag Res. 2018;10:6295–303.

Article  PubMed  PubMed Central  Google Scholar 

Yoshimizu S, Yoshio T, Ishiyama A, Tsuchida T, Horiuchi Y, Omae M, et al. Long-term outcomes of combined endoscopic resection and chemoradiotherapy for esophageal squamous cell carcinoma with submucosal invasion. Dig Liver Dis. 2018;50:833–8.

Article  PubMed  Google Scholar 

Shimizu Y, Kato M, Yamamoto J, Nakagawa S, Tsukagoshi H, Fujita M, et al. EMR combined with chemoradiotherapy: a novel treatment for superficial esophageal squamous-cell carcinoma. Gastrointest Endosc. 2004;59:199–204.

Article  PubMed  Google Scholar 

Suzuki G, Yamazaki H, Aibe N, Masui K, Sasaki N, Shimizu D, et al. Endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer: choice of new approach. Radiat Oncol. 2018;13:1–8.

Article  Google Scholar 

Koterazawa Y, Nakamura T, Oshikiri T, Kanaji S, Tanaka S, Ishida T, et al. A comparison of the clinical outcomes of esophagectomy and chemoradiotherapy after noncurative endoscopic submucosal dissection for esophageal squamous cell carcinoma. Surg Today. 2018;48:783–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hamada K, Ishihara R, Yamasaki Y, Hanaoka N, Yamamoto S, Arao M, et al. Efficacy and safety of endoscopic resection followed by chemoradiotherapy for superficial esophageal squamous cell carcinoma: a retrospective study. Clin Transl Gastroenterol. 2017;8:e110–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ishikura S, Nihei K, Ohtsu A, Boku N, Hironaka S, Mera K, et al. Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol Off J Am Soc Clin Oncol. 2003;21:2697–702.

Article  CAS  Google Scholar 

Kato K, Muro K, Minashi K, Ohtsu A, Ishikura S, Boku N, et al. Phase II study of chemoradiotherapy with 5-fluorouracil and cisplatin for Stage II-III esophageal squamous cell carcinoma: JCOG trial (JCOG 9906). Int J Radiat Oncol Biol Phys. 2011;81:684–90.

Article  CAS  PubMed  Google Scholar 

Xu C, Guo L, Liao Z, Wang Y, Liu X, Zhao S, et al. Heart and lung doses are independent predictors of overall survival in esophageal cancer after chemoradiotherapy. Clin Transl Radiat Oncol. 2019;17:17–23.

PubMed  PubMed Central  Google Scholar 

Groot C, Beukema JC, Langendijk JA, van der Laan HP, van Luijk P, van Melle JP, et al. Radiation-induced myocardial fibrosis in long-term esophageal cancer survivors. Int J Radiat Oncol Biol Phys. 2021;110:1013–21.

Article  PubMed  Google Scholar 

Pao TH, Chang WL, Chiang NJ, Chang JSM, Lin CY, Lai WW, et al. Cardiac radiation dose predicts survival in esophageal squamous cell carcinoma treated by definitive concurrent chemotherapy and intensity modulated radiotherapy. Radiat Oncol (Lond Eng). 2020;15:221.

Article  CAS  Google Scholar 

Takeuchi H, Ito Y, Machida R, Kato K, Onozawa M, Minashi K, et al. A single-arm confirmatory study of definitive chemoradiation therapy including salvage treatment for clinical stage II/III esophageal squamous cell carcinoma (JCOG0909 study). Int J Radiat Oncol Biol Phys. 2022;114:454–62.

Article  PubMed  Google Scholar