These authors contributed equally: Lanlin Hu, Mingxin Liu, Bo Tang.

These authors jointly supervised this work: Sijia Liu, Chuan Xu.

Yu-Yue Pathology Scientific Research Center, Chongqing, 400039, China

Lanlin Hu, Huani Wang & Chuan Xu

Jinfeng Laboratory, Chongqing, 401329, China

Lanlin Hu, Huani Wang & Chuan Xu

Department of Oncology & Cancer Institute, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China

Lanlin Hu, Bo Tang, Huani Wang, Dandan Wang & Chuan Xu

Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610042, China

Mingxin Liu

Cancer Center, Medical Research Institute, Southwest University, Chongqing, 400716, China

Xurui Li

Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China

Xurui Li

Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine & Guangxi Engineering Center in Biomedical Material for Tissue and Organ Regeneration & Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education, Guangxi Medical University, Nanning, 530021, China

Huasheng Xu & Sijia Liu

Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China

Dandan Wang & Chuan Xu