Does Scheduled Low-Dose Short-Term NSAID (Ketorolac) Modulate Cytokine Levels After Orthopaedic Polytrauma? A Secondary Analysis of a Randomized Clinical Trial

aDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA;

bDr Bing Zhang Department of Statistics, University of Kentucky, Lexington, KY;

cOrthoVirginia and Liberty University, Lynchburg, VA;

dDepartment of Trauma and Acute Care Surgery, University of Kentucky, Lexington, KY;

ePharmacy Practice & Science Department, University of Kentucky, Lexington, KY;

fDepartment of Orthopaedic Surgery & Sports Medicine, University of Kentucky, Lexington, KY; and

gUS Army Institute of Surgical Research, San Antonio, TX.

Reprints: Jeffrey A. Foster, MD, Department of Orthopaedic Surgery, Massachusetts General Hospital, Yawkey Outpatient Center, 3C 55 Fruit St., Boston, MA 02114 (e-mail: [email protected]).

This project described was aided by a grant from the Orthopaedic Trauma Association and was supported by the National Institutes of Health (NIH) National Center for Advancing Translational Sciences through grant number UL1TR001998. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

The authors report no conflict of interest.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jorthotrauma.com).

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