Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh

United Nations General Assembly. Transforming Our World: The 2030 Agenda for Sustainable Development (A/RES/70/1).; 2015. Accessed August 2, 2023. https://www.refworld.org/docid/57b6e3e44.html.

Blencowe, H. et al. Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010. Pediatr. Res. 74, 17–34 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Lee, A. C. C. et al. Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr. Res. 74, 50–72 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Lawn, J. E. et al. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting. Lancet 401, 1707–1719 (2023).

Article  PubMed  Google Scholar 

GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 396, 1204–1222 (2020).

Article  Google Scholar 

Chico, R. M. et al. Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review. JAMA 307, 2079–2086 (2012).

Article  CAS  PubMed  Google Scholar 

Collier, S. A., Rasmussen, S. A., Feldkamp, M. L. & Honein, M. A. National Birth Defects Prevention Study. Prevalence of self-reported infection during pregnancy among control mothers in the National Birth Defects Prevention Study. Birth Defects Res. Part A Clin. Mol. Teratol. 85, 193–201 (2009).

Article  CAS  Google Scholar 

Darmstadt, G. L. et al. 60 Million non-facility births: who can deliver in community settings to reduce intrapartum-related deaths? Int. J. Gynaecol. Obstet. 107, S89–S112 (2009).

Article  PubMed  PubMed Central  Google Scholar 

Lawn, J. E. et al. Two million intrapartum-related stillbirths and neonatal deaths: where, why, and what can be done? Int. J. Gynaecol. Obstet. 107, S5–S18 (2009). S19.

Article  PubMed  Google Scholar 

Black, R. E. et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet 382, 427–451 (2013).

Article  PubMed  Google Scholar 

Kozuki, N. et al. Short Maternal Stature Increases Risk of Small-for-Gestational-Age and Preterm Births in Low- and Middle-Income Countries: Individual Participant Data Meta-Analysis and Population Attributable Fraction. J. Nutr. 145, 2542–2550 (2015).

Article  CAS  PubMed  Google Scholar 

Shamim, A. A. et al. Plasma zinc, vitamin B(12) and α-tocopherol are positively and plasma γ-tocopherol is negatively associated with Hb concentration in early pregnancy in north-west Bangladesh. Public Health Nutr. 16, 1354–1361 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Vohr, B. R., Poggi Davis, E., Wanke, C. A. & Krebs, N. F. Neurodevelopment: The Impact of Nutrition and Inflammation During Preconception and Pregnancy in Low-Resource Settings. Pediatrics 139, S38–S49 (2017).

Article  PubMed  Google Scholar 

Méndez Leal, A. S. et al. Maternal early life stress is associated with pro-inflammatory processes during pregnancy. Brain Behav. Immun. 109, 285–291 (2023).

Article  PubMed  Google Scholar 

Sävman, K., Blennow, M., Gustafson, K., Tarkowski, E. & Hagberg, H. Cytokine response in cerebrospinal fluid after birth asphyxia. Pediatr. Res. 43, 746–751 (1998).

Article  PubMed  Google Scholar 

Foster-Barber, A., Dickens, B. & Ferriero, D. M. Human perinatal asphyxia: correlation of neonatal cytokines with MRI and outcome. Dev. Neurosci. 23, 213–218 (2001).

Article  CAS  PubMed  Google Scholar 

Leviton, A. et al. The relationship between early concentrations of 25 blood proteins and cerebral white matter injury in preterm newborns: the ELGAN study. J. Pediatr. 158, 897–903.e1 (2011).

Article  CAS  PubMed  Google Scholar 

Wu, Y. W. et al. Chorioamnionitis and cerebral palsy in term and near-term infants. JAMA 290, 2677–2684 (2003).

Article  CAS  PubMed  Google Scholar 

Volpe, J. J. Dysmaturation of premature brain: importance, cellular mechanisms, and potential interventions. Pediatr. Neurol. 95, 42–66 (2019).

Article  PubMed  Google Scholar 

Liddelow, S. A. et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature 541, 481–487 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Volpe, J. J. Microglia: Newly discovered complexity could lead to targeted therapy for neonatal white matter injury and dysmaturation. J. Neonatal Perinat. Med. 12, 239–242 (2019).

Article  CAS  Google Scholar 

Volpe, J. J., Kinney, H. C., Jensen, F. E. & Rosenberg, P. A. The developing oligodendrocyte: key cellular target in brain injury in the premature infant. Int J. Dev. Neurosci. 29, 423–440 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hagberg, H. et al. The role of inflammation in perinatal brain injury. Nat. Rev. Neurol. 11, 192–208 (2015).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Volpe, J. J. Neurobiology of periventricular leukomalacia in the premature infant. Pediatr. Res. 50, 553–562 (2001).

Article  CAS  PubMed  Google Scholar 

Inder, T. E., Anderson, N. J., Spencer, C., Wells, S. & Volpe, J. J. White matter injury in the premature infant: a comparison between serial cranial sonographic and MR findings at term. AJNR Am. J. Neuroradiol. 24, 805–809 (2003).

PubMed  PubMed Central  Google Scholar 

Volpe, J. J. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol. 8, 110–124 (2009).

Article  PubMed  PubMed Central  Google Scholar 

Dammann, O. & O’Shea, T. M. Cytokines and perinatal brain damage. Clin. Perinatol. 35, 643–663 (2008).

Article  PubMed  PubMed Central  Google Scholar 

McAdams, R. M. & Juul, S. E. The role of cytokines and inflammatory cells in perinatal brain injury. Neurol. Res. Int. 2012, 561494 (2012).

PubMed  PubMed Central  Google Scholar 

Back, S. A. White matter injury in the preterm infant: pathology and mechanisms. Acta. Neuropathol. 134, 331–349 (2017).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kuban, K. C. K. et al. Systemic inflammation and cerebral palsy risk in extremely preterm infants. J. Child Neurol. 29, 1692–1698 (2014).

Article  PubMed  PubMed Central  Google Scholar 

O’Shea, T. M. et al. Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infants. J. Pediatr. 160, 395–401.e4 (2012).

Article  PubMed  Google Scholar 

O’Shea, T. M. et al. Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants. Brain Behav. Immun. 29, 104–112 (2013).

Article  PubMed  PubMed Central  Google Scholar 

O’Shea, T. M. et al. Elevated blood levels of inflammation-related proteins are associated with an attention problem at age 24 mo in extremely preterm infants. Pediatr. Res. 75, 781–787 (2014).

Article  PubMed  PubMed Central  Google Scholar 

Leviton, A. et al. Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week. Early Hum. Dev. 87, 325–330 (2011).

Article  CAS  PubMed  Google Scholar 

Bartha, A. I. et al. Neonatal encephalopathy: association of cytokines with MR spectroscopy and outcome. Pediatr. Res. 56, 960–966 (2004).

Article  CAS  PubMed  Google Scholar 

Lee, A. C. C. et al. National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010. Lancet Glob. Health 1, e26–e36 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Arifeen, S. E. et al. The effect of cord cleansing with chlorhexidine on neonatal mortality in rural Bangladesh: a community-based, cluster-randomised trial. Lancet 379, 1022–1028 (2012).

Article  PubMed  Google Scholar 

AMANHI (Alliance for Maternal and Newborn Health Improvement). et al. Development and validation of a simplified algorithm for neonatal gestational age assessment - protocol for the Alliance for Maternal Newborn Health Improvement (AMANHI) prospective cohort study. J. Glob. Health 7, 021201 (2017).

Article  Google Scholar 

Villar, J. et al. International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. Lancet 384, 857–868 (2014).

Article  PubMed  Google Scholar 

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