Advances in Pharmacology and Pharmacy Vol. 13(3), pp. 333 - 341
DOI: 10.13189/app.2025.130305
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Kuchi Manjeera 1,2, Raja Sundararajan 2,*
1 Department of Pharmacology, CMR College of Pharmacy, Kandlakoya, Medchal, Hyderabad, Telangana, 501401, India
2 Department of Pharmaceutical Chemistry, GITAM School of Pharmacy, GITAM (Deemed to be University), India

ABSTRACT

Numerous diseases, such as cancer, diabetes mellitus, aging, arthritis are linked to free radicals. Antioxidant therapy has become increasingly important in the management of several illnesses. Diabetes mellitus is an intricate metabolic ailment characterized by insistent hyperglycemia that interferes with protein, lipid and carbohydrate metabolism. Therefore, using a variety of conventional in vitro models, a modern investigation sought to investigate the antioxidant and antidiabetic properties of Indigofera prostrata. The methanol extracts of Indigofera prostrata were assessed in this endeavor for their ability to block radicals via the use of superoxide radical action, DPPH, lipid peroxidation assay, and the nitric oxide method. Numerous factors, including glucose diffusion, the inhibitory actions of alpha amylase, alpha glucosidase, and the ability of yeast cells to absorb glucose, were also used to measure the in vitro antidiabetic efficacy. When compared to conventional antioxidants, the revealed results of plant extracts demonstrated a higher capability for radical scavenging in relation to their antioxidant activity. Similarly, a variety of characteristics demonstrated that in vitro extracts of Indigofera prostrata had excellent antidiabetic action. In summary, Indigofera prostrata has strong anti-oxidant and antidiabetic qualities.

KEYWORDS
Methanol Extract, In vitro Antioxidant and Antidiabetic Properties, Indigofera prostrata

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Kuchi Manjeera , Raja Sundararajan , "In vitro Antioxidant & Antidiabetic Activity of Indigofera prostrata," Advances in Pharmacology and Pharmacy, Vol. 13, No. 3, pp. 333 - 341, 2025. DOI: 10.13189/app.2025.130305.

(b). APA Format:
Kuchi Manjeera , Raja Sundararajan (2025). In vitro Antioxidant & Antidiabetic Activity of Indigofera prostrata. Advances in Pharmacology and Pharmacy, 13(3), 333 - 341. DOI: 10.13189/app.2025.130305.