Advances in Pharmacology and Pharmacy Vol. 13(3), pp. 377 - 389
DOI: 10.13189/app.2025.130309
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Pameshwar Kumar , Aarti Tiwari , Gulshan Athbhaiya , Pradeep Kumar Samal *
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), India

ABSTRACT

This study aims to investigate the hypolipidemic effects of an aqueous extract from the leaves of Raphanus sativus var. longipinnatus using rat models. Hyperlipidaemia, a condition caused by a high-fat diet, was produced in Wistar albino rats through the continuous administration of such food. During this period, weight growth and changes to the serum lipid profile were observed. It specifically indicated a reduction in high-density lipoprotein levels and an increase in total cholesterol (185±0.96), triglycerides (281±1.2), low-density lipoprotein (123±2.0), and very low-density lipoprotein (57±1.4). Atorvastatin administered at a dosage of 10 mg/kg served as the reference medication for the standardisation process. Following a 14-day testing period, rats administered 300 mg/kg of leaf extract exhibited a significant alteration in their weight. A significant increase (P

KEYWORDS
Raphanus sativus, Extract, Hyperlipidemia, Atorvastatin, Lipoprotein

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Pameshwar Kumar , Aarti Tiwari , Gulshan Athbhaiya , Pradeep Kumar Samal , "Hypolipidemic Action of Leaf Extracts of Raphanus sativus var. Longipinnatus in High Fat Diet Induced Rats," Advances in Pharmacology and Pharmacy, Vol. 13, No. 3, pp. 377 - 389, 2025. DOI: 10.13189/app.2025.130309.

(b). APA Format:
Pameshwar Kumar , Aarti Tiwari , Gulshan Athbhaiya , Pradeep Kumar Samal (2025). Hypolipidemic Action of Leaf Extracts of Raphanus sativus var. Longipinnatus in High Fat Diet Induced Rats. Advances in Pharmacology and Pharmacy, 13(3), 377 - 389. DOI: 10.13189/app.2025.130309.