Comparative Evaluation of Upfront Surgery and Neoadjuvant Chemotherapy Followed by Surgery in Locally Advanced Oral Squamous Cell Carcinoma

Dhar H, Vaish R, D’Cruz AK (2020) Management of locally advanced oral cancers. Oral Oncol 105:104662

Article  PubMed  Google Scholar 

Huang SH, Osullivan B (2017) Overview of the 8th edition TNM Classification for Head and Neck Cancer. Curr Treat Options Oncol. 18(7):40

Article  PubMed  Google Scholar 

Singh MP, Misra S, Rathanaswamy SP, Gupta S, Tewari BN, Bhatt ML et al (2015) Clinical profile and epidemiological factors of oral cancer patients from North India. Natl J Maxillofac Surg. 6(1):21–4

Article  PubMed  PubMed Central  Google Scholar 

Pulte D, Brenner H (2010) Changes in survival in head and neck cancers in the late 20th and early 21st century: a period analysis. Oncologist 15:994–1001

Article  PubMed  PubMed Central  Google Scholar 

Alzahrani R, Obaid A, Al-Hakami H, Alshehri A, Al-Assaf H, Adas R et al (2020) Locally advanced oral cavity cancers: what is the optimal care? Cancer Control. 27(1):1073274820920727

Article  PubMed  PubMed Central  Google Scholar 

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68(6):394–424

Article  PubMed  Google Scholar 

de Oliveira TB, Marta GN, de Castro JG, Kowalski LP (2021) Induction chemotherapy for advanced oral cavity cancer. Curr Oncol Rep 23(11):129

Article  PubMed  Google Scholar 

Foote RL, Gilbert J, Gillison ML, et al. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Head and Neck Cancers; 2018. https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf. Accessed July 25, 2023.

Hanna GJ, Haddad RI, Lorch JH (2013) Induction chemotherapy forlocoregionally advanced head and neck cancer: past, present, future? Oncologist 18:288–293

Article  PubMed  PubMed Central  Google Scholar 

Licitra L, Grandi C, Guzzo M et al (2003) Primary chemotherapy in resectable oral cavity squamous cell cancer: a randomized controlled trial. J Clin Oncol 21(2):327–333

Article  CAS  PubMed  Google Scholar 

Zhong LP, Zhang CP, Ren GX et al (2013) Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma. J Clin Oncol 31(6):744–751

Article  CAS  PubMed  Google Scholar 

Patil VM, Prabhash K, Noronha V et al (2014) Neoadjuvant chemotherapy followed by surgery in very locally advanced technically unresectable oral cavity cancers. Oral Oncol 50(10):1000–1004

Article  CAS  PubMed  Google Scholar 

Amin MB, E.S., Greene FL et al. (207) AJCC Cancer Staging Manual. 8th ed. Springer International Publishing: American Joint Commission on Cancer; 2017, New York

Bernier J, Cooper JS, Pajak TF, van Glabbeke M, Bourhis J, Forastiere A et al (2005) Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501). Head Neck 27(10):843–850

Article  PubMed  Google Scholar 

Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R et al (2009) New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 45(2):228–47

Article  CAS  PubMed  Google Scholar 

Bossi P, Lo Vullo S, Guzzo M et al (2014) Preoperative chemotherapy in advanced resectable OCSCC: long-term results of a randomized phase III trial. Ann Oncol 25(2):462–466

Article  CAS  PubMed  Google Scholar 

Marta GN, Riera R, Bossi P et al (2015) Induction chemotherapy prior to surgery with or without postoperative radiotherapy for oral cavity cancer patients: systematic review and meta-analysis. Eur J Cancer 51(17):2596–2603

Article  PubMed  Google Scholar 

Sadighi S, Keyhani A, Harirchi I et al (2015) Neoadjuvant chemotherapy for locally advanced squamous carcinoma of oral cavity: a pilot study. Acta Med Iran 53(6):380–386

PubMed  Google Scholar 

Rudresha A, Chaudhuri T, Lakshmaiah K et al (2017) Induction chemotherapy in locally advanced T4b oral cavity squamous cell cancers: a regional cancer center experience. Indian J Cancer 54(1):35

Article  CAS  PubMed  Google Scholar 

Joshi A, Patil VM, Noronha V et al (2013) Is there a role of induction chemotherapy followed by resection in T4b oral cavity cancers? Indian J Cancer 50(4):349

Article  CAS  PubMed  Google Scholar 

Rudresha A, Chaudhuri T, Lakshmaiah K et al (2017) Induction chemotherapy in technically unresectable locally advanced T4a oral cavity squamous cell cancers: experience from a regional cancer center of South India. Indian J Med Paediatr Oncol 38(4):490

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thiagarajan S, Dhar H, Bhattacharjee A et al (2020) Patterns of failure and outcomes in cT4 Oral squamous cell carcinoma (OSCC) undergoing upfront surgery in comparison to Neo-Adjuvant Chemotherapy (NACT) followed by surgery: a matched pair analysis. Oral Oncol 100:104455

Article  PubMed  Google Scholar 

Lacas B, Carmel A, Landais C et al (2021) MACH-NC Collaborative Group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group. Radiother Oncol 156:281–293

Article  PubMed  PubMed Central  Google Scholar 

Pai PS, Vaidya AD, Prabhash K et al (2013) Oral metronomic scheduling of anticancer therapy-based treatment compared to existing standard of care in locally advanced oral squamous cell cancers: a matched-pair analysis. Indian J Cancer 50:135–141

Article  CAS  PubMed  Google Scholar 

Patil VM, Noronha V, Joshi A, Banavali SD, Muddu V, Prabhash K (2016) Preoperative chemotherapy and metronomic scheduling of chemotherapy in locally advanced oral cancers. Oncology 91(Suppl 1):35–40

Article  PubMed  Google Scholar 

Vermorken JB, Remenar E, van Herpen C et al (2007) Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. N Engl J Med 357:1695–1704

Article  CAS  PubMed  Google Scholar 

Posner MR, Hershock DM, Blajman CR et al (2007) Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med 357:1705–1715

Article  CAS  PubMed  Google Scholar 

Haddad R, O’Neill A, Rabinowits G et al (2013) Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial. Lancet Oncol 14:257–264

Article  CAS  PubMed  Google Scholar 

Cohen EEW, Karrison TG, Kocherginsky M et al (2014) Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer. J Clin Oncol 32:2735–2743

Article  CAS  PubMed  PubMed Central  Google Scholar 

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