Innovative nanoparticle strategies for treating oral cancers

Hakim SG, Su YR. Study and treatment of oral squamous cell carcinoma-insights and perspectives. Cancers (Basel) 2023;15(20).

Cheng Y, Wang L, Zhang S, Jian W, Zeng B, Liang L, Deng Z. The investigation of Nfκb inhibitors to block cell proliferation in OSCC cells lines. Curr Med Chem. 2024.

Yuan W, Tan T, Lu L, Lu C, Zhang Y, Liu B. Surfeit 4 regulates aerobic glycolysis to enhanced proliferation, tumor stemness, invasion, and metastasis in oral squamous cell carcinoma. CytoJournal. 2024;21:60.

Article  PubMed  PubMed Central  Google Scholar 

Miller KD, Nogueira L, Devasia T, Mariotto AB, Yabroff KR, Jemal A, Kramer J, Siegel RL. Cancer treatment and survivorship statistics, 2022. CA Cancer J Clin. 2022;72(5):409–36.

Article  PubMed  Google Scholar 

Pan Z, Zhang X, Xie W, Cui J, Wang Y, Zhang B, Du L, Zhai W, Sun H, Li Y. Revisited and innovative perspectives of oral ulcer: from biological specificity to local treatment. Front Bioeng Biotechnol. 2024;12:1335377.

Article  PubMed  PubMed Central  Google Scholar 

Yao Y, Zhou Y, Liu L, Xu Y, Chen Q, Wang Y, Wu S, Deng Y, Zhang J, Shao A. Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance. Front Mol Biosci. 2020;7:193.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Patra JK, Das G, Fraceto LF, Campos EVR, Rodriguez-Torres MDP, Acosta-Torres LS, Diaz-Torres LA, Grillo R, Swamy MK, Sharma S, et al. Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnology. 2018;16(1):71.

Article  PubMed  PubMed Central  Google Scholar 

Fathi-Karkan S, Heidarzadeh M, Narmi MT, Mardi N, Amini H, Saghati S, Abrbekoh FN, Saghebasl S, Rahbarghazi R, Khoshfetrat AB. Exosome-loaded microneedle patches: promising factor delivery route. Int J Biol Macromol. 2023;243: 125232.

Article  CAS  PubMed  Google Scholar 

Hameed Y, Nabi-Afjadi M, Gu Y, Wu L. Cell membrane-coated nanoparticles for cancer therapy. Cancer Insight. 2023;2(1):145–62.

Google Scholar 

Zhang Y, Wu Y, Du H, Li Z, Bai X, Wu Y, Li H, Zhou M, Cao Y, Chen X. Nano-drug delivery systems in oral cancer therapy: recent developments and prospective. Pharmaceutics. 2023;16(1):7.

Article  PubMed  PubMed Central  Google Scholar 

Ketabat F, Pundir M, Mohabatpour F, Lobanova L, Koutsopoulos S, Hadjiiski L, Chen X, Papagerakis P, Papagerakis S. Controlled drug delivery systems for oral cancer treatment-current status and future perspectives. Pharmaceutics. 2019;11(7).

Fathi-karkan S, Zeeshan M, Qindeel M, Malekshah RE, Rahdar A, Ferreira LFR. NPs loaded with zoledronic acid as an advanced tool for cancer therapy. J Drug Deliv Sci Technol. 2023;87: 104805.

Article  CAS  Google Scholar 

Vyas K, Rathod M, Patel MM. Insight on nano drug delivery systems with targeted therapy in treatment of oral cancer. Nanomed Nanotechnol Biol Med. 2023;49:102662.

Article  CAS  Google Scholar 

Date T, Nimbalkar V, Kamat J, Mittal A, Mahato RI, Chitkara D. Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics. J Control Release. 2018;271:60–73.

Article  CAS  PubMed  Google Scholar 

Calixto G, Bernegossi J, Fonseca-Santos B, Chorilli M. Nanotechnology-based drug delivery systems for treatment of oral cancer: a review. Int J Nanomed. 2014:3719–3735.

Zlotogorski A, Dayan A, Dayan D, Chaushu G, Salo T, Vered M. Nutraceuticals as new treatment approaches for oral cancer: II. Green tea extracts and resveratrol. Oral Oncol. 2013;49(6):502–6.

Article  CAS  PubMed  Google Scholar 

Masuelli L, Di Stefano E, Fantini M, Mattera R, Benvenuto M, Marzocchella L, Sacchetti P, Focaccetti C, Bernardini R, Tresoldi I. Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas. Oncotarget. 2014;5(21):10745.

Article  PubMed  PubMed Central  Google Scholar 

Far BF, Maleki-Baladi R, Fathi-Karkan S, Babaei M, Sargazi S. Biomedical applications of cerium vanadate nanoparticles: a review. J Mater Chem B. 2024;12(3):609–36.

Article  Google Scholar 

Gao Y, Wang Y, Jiang J, Wei P, Sun H. Triggered “on/off” luminescent polypeptide bowl‐shaped nanoparticles for selective lighting of tumor cells. Small 2025:2411432.

Dang Y, Guan J. Nanoparticle-based drug delivery systems for cancer therapy. Smart Mater Med. 2020;1:10–9.

Article  PubMed  PubMed Central  Google Scholar 

Niza E, Ocana A, Castro-Osma J, Bravo I, Alonso-Moreno C. Polyester polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment. Cancers. 2021;13:3387.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Torres-Martinez Z, Delgado Y, Ferrer-Acosta Y, Suarez-Arroyo IJ, Joaquín-Ovalle FM, Delinois LJ, Griebenow K. Key genes and drug delivery systems to improve the efficiency of chemotherapy. Cancer Drug Resistance. 2021;4(1):163.

CAS  PubMed  PubMed Central  Google Scholar 

Cheng S-H, Li F-C, Souris JS, Yang C-S, Tseng F-G, Lee H-S, Chen C-T, Dong C-Y, Lo L-W. Visualizing dynamics of sub-hepatic distribution of nanoparticles using intravital multiphoton fluorescence microscopy. ACS Nano. 2012;6(5):4122–31.

Article  CAS  PubMed  Google Scholar 

Iavicoli I, Fontana L, Nordberg G. The effects of nanoparticles on the renal system. Crit Rev Toxicol. 2016;46(6):490–560.

Article  CAS  PubMed  Google Scholar 

Lila ASA, Kiwada H, Ishida T. The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage. J Control Release. 2013;172(1):38–47.

Article  PubMed  Google Scholar 

Agrahari V, Agrahari V. Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities. Drug Discov Today. 2018;23(5):974–91.

Article  PubMed  Google Scholar 

Kumarasamy RV, Natarajan PM, Umapathy VR, Roy JR, Mironescu M, Palanisamy CP. Clinical applications and therapeutic potentials of advanced nanoparticles: a comprehensive review on completed human clinical trials. Front Nanotechnol. 2024;6.

Tian H, Zhang T, Qin S, Huang Z, Zhou L, Shi J, Nice EC, Xie N, Huang C, Shen Z. Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies. J Hematol Oncol. 2022;15(1):132.

Article  PubMed  PubMed Central  Google Scholar 

Liu X, He F, Liu M. New opportunities of stimulus-responsive smart nanocarriers in cancer therapy. Nano Mater Sci. 2024.

Chehelgerdi M, Chehelgerdi M, Allela OQB, Pecho RDC, Jayasankar N, Rao DP, Thamaraikani T, Vasanthan M, Viktor P, Lakshmaiya N, et al. Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation. Mol Cancer. 2023;22(1):169.

Article  PubMed  PubMed Central  Google Scholar 

Yu B, Tai HC, Xue W, Lee LJ, Lee RJ. Receptor-targeted nanocarriers for therapeutic delivery to cancer. Mol Membr Biol. 2010;27(7):286–98.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu M, Fang X, Yang Y, Wang C. Peptide-enabled targeted delivery systems for therapeutic applications. Front Bioeng Biotechnol. 2021;9.

Stimphil E, Nagesetti A, Guduru R, Stewart T, Rodzinski A, Liang P, Khizroev S. Physics considerations in targeted anticancer drug delivery by magnetoelectric nanoparticles. Appl Phys Rev. 2017;4(2).

Gavas S, Quazi S, Karpiński TM. Nanoparticles for cancer therapy: current progress and challenges. Nanoscale Res Lett. 2021;16(1):173.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu C, Wang M, Zhang H, Li C, Zhang T, Liu H, Zhu S, Chen J. Tumor microenvironment and immunotherapy of oral cancer. Eur J Med Res. 2022;27(1):198.

Article  PubMed  PubMed Central  Google Scholar 

Babu S, Manavalan MJ, Jasmine Sh, Krishnan M. Tumor microenvironment in oral squamous cell carcinoma: implications for novel therapies. Oral Oncol Rep. 2024;12:100666.

Article  Google Scholar 

Wright K, Ly T, Kriet M, Czirok A, Thomas SM. Cancer-associated fibroblasts: master tumor microenvironment modifiers. Cancers (Basel). 2023;15(6).

Wu F, Yang J, Liu J, Wang Y, Mu J, Zeng Q, Deng S, Zhou H. Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer. Signal Transduct Target Ther. 2021;6(1):218.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xue VW, Chung JY, Córdoba CAG, Cheung AH, Kang W, Lam EW, Leung KT, To KF, Lan HY, Tang PM. Transforming growth factor-β: a multifunctional regulator of cancer immunity. Cancers (Basel). 2020;12(11).

Batlle E, Massagué J. Transforming growth factor-β signaling in immunity and cancer. Immunity. 2019;50(4):924–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sarkar M, Nguyen T, Gundre E, Ogunlusi O, El-Sobky M, Giri B, Sarkar TR. Cancer-associated fibroblasts: the chief architect in the tumor microenvironment. Front Cell Dev Biol. 2023;11:1089068.

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