Beebe DC, Holekamp NM, Shui YB (2010) Oxidative damage and the prevention of age-related cataracts. Ophthalmic Res 44(3):155–165

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao X, Song Y, Huang LL, Tian YJ, Wang XL, Hua LY (2022) M(6)a transferase METTL3 regulates endothelial-mesenchymal transition in diabetic retinopathy via lncRNA SNHG7/KHSRP/MKL1 axis. Genomics 114(6):110498

Article  CAS  PubMed  Google Scholar 

Cataract (2015) Nat Rev Dis Primers 1:15045

Article  Google Scholar 

Gao P, Cao M (2023) Cannabinoid receptor 2-centric molecular feedback loop drives necroptosis in diabetic heart injuries. Circulation 147(2):158–174

Article  CAS  PubMed  Google Scholar 

He M, Wang W, Huang W (2017) Variations and trends in health burden of visual impairment due to cataract: a global analysis. Invest Ophthalmol Vis Sci 58(10):4299–4306

Article  PubMed  Google Scholar 

Hu J, Lin Y (2020) Fusarium infection alters the m(6)A-modified transcript landscape in the cornea. Exp Eye Res 200:108216

Article  CAS  PubMed  Google Scholar 

Hu Q, Xu T, Zhang W, Huang C (2022) Bach2 regulates B cell survival to maintain germinal centers and promote B cell memory. Biochem Biophys Res Commun 618:86–92

Article  CAS  PubMed  Google Scholar 

Huang C, Geng H, Boss I, Wang L, Melnick A (2014) Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation. Blood 123(7):1012–1020

Article  CAS  PubMed  PubMed Central  Google Scholar 

Igarashi K, Kurosaki T, Roychoudhuri R (2017) BACH transcription factors in innate and adaptive immunity. Nat Rev Immunol 17(7):437–450

Article  CAS  PubMed  Google Scholar 

Itoh-Nakadai A, Matsumoto M, Kato H, Sasaki J, Uehara Y, Sato Y et al (2017) A Bach2-Cebp gene regulatory network for the commitment of multipotent hematopoietic progenitors. Cell Rep 18(10):2401–2414

Article  CAS  PubMed  Google Scholar 

Jia R, Chai P, Wang S, Sun B, Xu Y, Yang Y (2019) M(6)a modification suppresses ocular melanoma through modulating HINT2 mRNA translation. Mol Cancer 18(1):161

Article  PubMed  PubMed Central  Google Scholar 

Jiang Y, Zhang X, Zhang X, Zhao K, Zhang J, Yang C et al (2021) Comprehensive analysis of the transcriptome-wide m6A methylome in Pterygium by MeRIP sequencing. Front Cell Dev Biol 9:670528

Article  PubMed  PubMed Central  Google Scholar 

Jiang L, Liu X, Hu X, Gao L, Zeng H, Wang X et al (2022) METTL3-mediated m(6)a modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy. Mol Ther 30(4):1721–1740

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jing FY, Zhou LM, Ning YJ, Wang XJ, Zhu YM (2021) The biological function, mechanism, and clinical significance of m6A RNA modifications in head and neck carcinoma: a systematic review. Front Cell Dev Biol 9:683254

Article  PubMed  PubMed Central  Google Scholar 

Kawamoto M, Kohi S, Abe T, Dbouk M, Macgregor-Das A, Koi C et al (2022) Endoplasmic stress-inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: a case-control study and meta-analysis. Int J Cancer 150(7):1123–1133

Article  CAS  PubMed  Google Scholar 

Li SX, Yan W, Liu JP, Zhao YJ, Chen L (2021) Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 - mediated m(6)a level of STAT2 mRNA. Mol Immunol 139:10–22

Article  CAS  PubMed  Google Scholar 

Li D, He J, Fang C, Zhang Y, He M, Zhang Z et al (2023a) METTL3 regulates osteoclast biological behaviors via iNOS/NO-mediated mitochondrial dysfunction in inflammatory conditions. Int J Mol Sci 24(2):1403

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li R, Zhu H, Li Q, Tang J, Jin Y, Cui H (2023b) METTL3-mediated m6A modification of has_circ_0007905 promotes age-related cataract progression through miR-6749-3p/EIF4EBP1. PeerJ 11:e14863

Article  PubMed  PubMed Central  Google Scholar 

Li X, Peng X, Zhou X, Li M, Chen G, Shi W et al (2023c) Small extracellular vesicles delivering lncRNA WAC-AS1 aggravate renal allograft ischemia–reperfusion injury by inducing ferroptosis propagation. Cell Death Differ 30(9):2167–2186

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu YC, Wilkins M, Kim T, Malyugin B, Mehta JS (2017) Cataracts Lancet 390(10094):600–612

Article  PubMed  Google Scholar 

Liu X, Su K, Kuang S, Fu M, Zhang Z (2020) Mir-16-5p and mir-145-5p trigger apoptosis in human gingival epithelial cells by down-regulating BACH2. Int J Clin Exp Pathol 13(5):901–911

CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Gu C, Li X, Wang T, Yu L (2021) Involvement of METTL3/m(6)Adenosine and TGFβ/Smad3 signaling on Tenon’s fibroblasts and in a rabbit model of glaucoma surgery. J Mol Histol 52(6):1129–1144

Article  CAS  PubMed  Google Scholar 

Ma DY, Liu JX, Wang LD, Zhi XY, Luo L, Zhao JY et al (2023) GSK-3β-dependent Nrf2 antioxidant response modulates ferroptosis of lens epithelial cells in age-related cataract. Free Radic Biol Med 204:161–176

Article  CAS  PubMed  Google Scholar 

Ma L, Chang X, Gao J, Zhang Y, Chen Y, Zhou H et al (2024) METTL3 boosts mitochondrial fission and induces cardiac fibrosis after ischemia/reperfusion injury. Int J Biol Sci 20(2):433–445

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marinkovic DV, Marinkovic JN, Erdös EG, Robinson CJ (1977) Purification of carboxypeptidase B from human pancreas. Biochem J 163(2):253–260

Article  CAS  PubMed  PubMed Central  Google Scholar 

Muto A, Tashiro S, Nakajima O, Hoshino H, Takahashi S, Sakoda E et al (2004) The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429(6991):566–571

Article  CAS  PubMed  Google Scholar 

Napier BA, Brubaker SW, Sweeney TE (2016) Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity. J Exp Med 213(11):2365–2382

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pousette A, Fernstad R, Sköldefors H, Carlström K (1988) Novel assay for pancreatic cellular damage: 1. Characterization of protein profiles in human pancreatic cytosol and purification and characterization of a pancreatic specific protein. Pancreas 3(4):421–426

Article  CAS  PubMed  Google Scholar 

Sheng H, Li Z, Su S, Sun W, Zhang X, Li L et al (2020) YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation. Carcinogenesis 41(5):541–550

Article  CAS  PubMed  Google Scholar 

Son J, Ding H, Farb TB, Efanov AM, Sun J, Gore JL et al (2021) BACH2 inhibition reverses β cell failure in type 2 diabetes models. J Clin Invest 131(24):e153876

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun D, Cui H, Rong L, Ma T, Li X, Ye Z et al (2024) Sestrin2 protects human lens epithelial cells (HLECs) against apoptosis in cataracts formation: interaction between endoplasmic reticulum (ER) stress and oxidative stress (OS) is involved. Curr Eye Res