De Courcy L, Bezak E, Marcu LG (2020) Gender-dependent radiotherapy: the next step in personalised medicine? Crit Rev Oncol Hematol 147:102881. https://doi.org/10.1016/j.critrevonc.2020.102881

Article  PubMed  Google Scholar 

Alsbeih G, Al-Meer RS, Al-Harbi N, Bin Judia S, Al-Buhairi M, Venturina NQ, Moftah B (2016) Gender bias in individual radiosensitivity and the association with genetic polymorphic variations. Radiother Oncol 119:236–243. https://doi.org/10.1016/j.radonc.2016.02.034

Article  PubMed  Google Scholar 

Barnett GC, Coles CE, Elliott RM, Baynes C, Luccarini C, Conroy D, Wilkinson JS, Tyrer J, Misra V, Platte R, Gulliford SL, Sydes MR, Hall E, Bentzen SM, Dearnaley DP, Burnet NG, Pharoah PD, Dunning AM, West CM (2012) Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. Lancet Oncol 13:65–77. https://doi.org/10.1016/S1470-2045(11)70302-3

Article  CAS  PubMed  Google Scholar 

Huynh TTM, Aass HCD, Falk RS, Astrup GL, Helland Å, Bjøro T, Bjordal K, Dale E, Hellebust TP, Herlofson BB, Malinen E, Kiserud CE, Osnes T, Amdal CD (2023) Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy. J Cancer Surviv 17:1082–1093. https://doi.org/10.1007/s11764-022-01273-1

Article  CAS  PubMed  Google Scholar 

Cui L, Chen Z, Zeng F, Jiang X, Han X, Yuan X, Wu S, Feng H, Lin D, Lu W, Liu X, Peng X, Yu B (2023) Impact of sex on treatment-related adverse effects and prognosis in nasopharyngeal carcinoma. BMC Cancer 23(1):1146. https://doi.org/10.1186/s12885-023-11564-0

Article  CAS  PubMed Central  PubMed  Google Scholar 

van Erning FN, Greidanus NEM, Verhoeven RHA, Buijsen J, de Wilt HW, Wagner D, Creemers GJ (2023) Gender differences in tumor characteristics, treatment and survival of colorectal cancer: a population-based study. Cancer Epidemiol 86:102441. https://doi.org/10.1016/j.canep.2023.102441

Article  PubMed  Google Scholar 

Zhou J, Wang Z, Chen X, Li Q (2023) Gender differences in psychosocial outcomes and coping strategies of patients with colorectal cancer: a systematic review. Healthcare 11(18):2591. https://doi.org/10.3390/healthcare11182591

Article  PubMed Central  PubMed  Google Scholar 

Jacobs-Lawson JM, Schumacher MM, Hughes T, Arnold S (2010) Gender differences in psychosocial responses to lung cancer. Gend Med 7:137–148. https://doi.org/10.1016/j.genm.2010.03.002

Article  PubMed  Google Scholar 

Csuka SI, Rohánszky M, Konkolÿ Thege B (2024) Gender differences in the predictors of quality of life in patients with cancer: a cross-sectional study. Eur J Oncol Nurs 68:102492. https://doi.org/10.1016/j.ejon.2023.102492

Article  PubMed  Google Scholar 

Yao Z, Fang L, Yu Y, Zhang Z, Zheng W, Li Z, Li Y, Zhao Y, Hu T, Zhang Z, Hu B (2019) Gender-disease interaction on brain cerebral metabolism in cancer patients with depressive symptoms. BMC Psychiatry 19(1):14. https://doi.org/10.1186/s12888-018-2002-6

Article  PubMed Central  PubMed  Google Scholar 

De Felice F, Locati LD, Ronchi S, Thariat J, Orlandi E (2022) Quality of life and financial toxicity after (chemo)radiation therapy in head and neck cancer: are there any sex- or gender-related differences? Tumori 108:522–525. https://doi.org/10.1177/03008916221078885

Article  PubMed  Google Scholar 

Heidari S, Babor TF, De Castro P, Tort S, Curno M (2016) Sex and gender equity in research: rationale for the SAGER guidelines and recommended use. Res Integr Peer Rev 1:2. https://doi.org/10.1186/s41073-016-0007-6 (Erratum in: Res Integr Peer Rev. 2024 Dec 20;9(1):15. https://doi.org/10.1186/s41073-024-00155-7)

Article  PubMed Central  PubMed  Google Scholar 

Dahill A, Al-Nakishbandi H, Cunningham KB, Humphris GM, Lowe D, Rogers SN (2020) Loneliness and quality of life after head and neck cancer. Br J Oral Maxillofac Surg 58:959–965. https://doi.org/10.1016/j.bjoms.2020.04.041

Article  CAS  PubMed  Google Scholar 

Hammermüller C, Hinz A, Dietz A, Wichmann G, Pirlich M, Berger T, Zimmermann K, Neumuth T, Mehnert-Theuerkauf A, Wiegand S (2021) Depression, anxiety, fatigue, and quality of life in a large sample of patients suffering from head and neck cancer in comparison with the general population. BMC Cancer 21:1–11. https://doi.org/10.1186/s12885-020-07773-6

Article  Google Scholar 

Fan CY, Chao HL, Lin CS, Huang WY, Chen CM, Lin KT, Lin CL, Kao CH (2018) Risk of depressive disorder among patients with head and neck cancer: a nationwide population-based study. Head Neck 40:312–323. https://doi.org/10.1002/hed.24961

Article  PubMed  Google Scholar 

Mugge L, Mansour TR, Crippen M, Alam Y, Schroeder J (2020) Depression and glioblastoma, complicated concomitant diseases: a systemic review of published literature. Neurosurg Rev 43:497–511. https://doi.org/10.1007/s10143-018-1017-2

Article  PubMed  Google Scholar 

Robles P, Fiest KM, Frolkis AD (2015) The worldwide incidence and prevalence of primary brain tumors: a systematic review and meta-analysis. Neuro Oncol 17:776–783. https://doi.org/10.1093/neuonc/nou283

Article  PubMed  Google Scholar 

Qaderi SM, van der Heijden JAG, Verhoeven RHA, de Wilt JHW, Custers JAE, PLCRC study group (2021) Trajectories of health-related quality of life and psychological distress in patients with colorectal cancer: a population-based study. Eur J Cancer 158(34666216):144–155. https://doi.org/10.1016/j.ejca.2021.08.050

Article  PubMed  Google Scholar 

Phelan SM, Griffin JM, Jackson GL, Zafar SY, Hellerstedt W, Stahre M, Nelson D, Zullig LL, Burgess DJ, van Ryn M (2013) Stigma, perceived blame, self-blame, and depressive symptoms in men with colorectal cancer. Psychooncology 22:65–73. https://doi.org/10.1002/pon.2048

Article  PubMed  Google Scholar 

Tagliaferri L, Mancini S, Lancellotta V, Dinapoli L, Capocchiano N, Cornacchione P, Scalise S, Autorino R, Campitelli M, Ferdinando Colloca G, Fionda B, Rovirosa A, Macchia G, Ferrandina G, Gambacorta MA (2023) The impact of HAPPY (humanity assurance protocol in Interventional radiotherapy) on the psychological well-being of gynecological cancer patients. Curr Radiopharm. https://doi.org/10.2174/0118744710247426230925054848

Article  Google Scholar 

Casà C, Dinapoli L, Marconi E, Chiesa S, Cornacchione P, Beghella Bartoli F, Bracci S, Salvati A, Scalise S, Colloca GF, Chieffo DPR, Gambacorta MA, Valentini V, Tagliaferri L (2023) Integration of art and technology in personalized radiation oncology care: experiences, evidence, and perspectives. Front Public Health 23(11):1056307. https://doi.org/10.3389/fpubh.2023.1056307

Article  Google Scholar 

Dinapoli L, Chiesa S, Dinapoli N, Gatta R, Beghella Bartoli F, Bracci S, Mazzarella C, Sanfilippo MZ, Sabatino G, Gaudino S, Della Pepa GM, Frascino V, Valentini V, Balducci M (2021) Personalised support of brain tumour patients during radiotherapy based on psychological profile and quality of life. Support Care Cancer 29:4555–4563. https://doi.org/10.1007/s00520-021-06000-7

Article  PubMed  Google Scholar 

Dinapoli L, Massaccesi M, Colloca G, Tenore A, Dinapoli N, Valentini V (2019) Efficacy of an eye movement desensitization and reprocessing (EMDR) intervention for a head and neck cancer patient with intolerable anxiety undergoing radiotherapy. Psychooncology 28:647–649. https://doi.org/10.1002/pon.5000

Article  PubMed  Google Scholar 

Wang GL, Hsu SH, Feng AC, Chiu CY, Shen JF, Lin YJ, Cheng CC (2011) The HADS and the DT for screening psychosocial distress of cancer patients in Taiwan. Psychooncology 20:639–646. https://doi.org/10.1002/pon.1952

Article  CAS  PubMed  Google Scholar 

Grassi L, Johansen C, Annunziata MA, Capovilla E, Costantini A, Gritti P, Torta R, Bellani M, Italian Society of Psycho-Oncology Distress Thermometer Study Group (2013) Screening for distress in cancer patients: a multicenter, nationwide study in Italy. Cancer 119:1714–1721. https://doi.org/10.1002/cncr.27902

Article  PubMed  Google Scholar 

Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361–370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x

Article  CAS  PubMed  Google Scholar 

Moorey S, Greer S, Watson M, Gorman C, Rowden L, Tunmore R, Robertson B, Bliss J (1991) The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer. Br J Psychiatry 158:255–259. https://doi.org/10.1192/bjp.158.2.255

Article  CAS  PubMed  Google Scholar 

Chiesa S, Marconi E, Dinapoli N, Sanfilippo MZ, Ruggiero A, Mastronuzzi A, Panza G, Serra A, Massaccesi M, Cacchione A, Beghella Bartoli F, Chieffo DPR, Gambacorta MA, Valentini V, Balducci M (2021) The Multidimensional Assessment for Pediatric Patients in Radiotherapy (M.A.P.-RT) Tool for Customized Treatment Preparation: RADAR Project. Front Oncol 29(1):621690. https://doi.org/10.3389/fonc.2021.621690

Article  Googl