Patterns of incident Burkitt lymphoma during the HIV epidemic among the Black African and White population in South Africa

Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, et al. Burkitt’s lymphoma. Lancet. 2012;379:1234–44.

Article  PubMed  Google Scholar 

Gastwirt JP, Roschewski M. Management of adults with Burkitt lymphoma. Clin Adv Hematol Oncol. 2018;16:812–22.

PubMed  Google Scholar 

Mbulaiteye SM, Devesa SS. Burkitt lymphoma incidence in five continents. Hemato. 2022;3:434–53.

Article  Google Scholar 

López C, Burkhardt B, Chan JKC, Leoncini L, Mbulaiteye SM, Ogwang MD, et al. Burkitt lymphoma. Nat Rev Dis Primers. 2022;8:78.

Mbulaiteye SM, Anderson WF, Bhatia K, Rosenberg PS, Linet MS, Devesa SS. Trimodal age-specific incidence patterns for Burkitt lymphoma in the United States, 1973-2005. Int J Cancer. 2010;126:1732–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dhokotera T, Bohlius J, Spoerri A, Egger M, Ncayiyana J, Olago V, et al. The burden of cancers associated with HIV in the South African public health sector, 2004-2014: a record linkage study. Infect Agent Cancer. 2019;14:1–12.

Article  Google Scholar 

Hernández-Ramírez RU, Shiels MS, Dubrow R, Engels EA. Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study. Lancet HIV. 2017;4:e495–504.

Article  PubMed  PubMed Central  Google Scholar 

Mdletshe N, Nel A, Shires K, Mowla S. HIV Nef enhances the expression of oncogenic c-MYC and activation-induced cytidine deaminase in Burkitt lymphoma cells, promoting genomic instability. Infect Agent Cancer. 2020;15:54.

Felli MP, Mowla S, Alves L, Rios S, Mapekula L, Mdletshe N, et al. HIV-1 transactivator of transcription (Tat) co-operates with AP-1 factors to enhance c-MYC transcription. Front Cell Dev Biol. 2021;9:693706.

Martorelli D, Muraro E, Mastorci K, Dal Col J, Faè DA, Furlan C, et al. A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting. Int J Cancer. 2015;137:1374–85.

Article  CAS  PubMed  Google Scholar 

Engels EA, Pfeiffer RM, Goedert JJ, Virgo P, Mcneel TS, Scoppa SM, et al. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS. 2006;20:1645–54.

Article  PubMed  Google Scholar 

Shiels MS, Engels EA, Linet MS, Clarke CA, Li J, Hall HI, et al. The epidemic of non-Hodgkin lymphoma in the United States: disentangling the effect of HIV, 1992-2009. Cancer Epidemiol Biomark Prev. 2013;22:1069–78.

Article  Google Scholar 

Gibson TM, Morton LM, Shiels MS, Clarke CA, Engels EA. Risk of non-Hodgkin lymphoma subtypes in HIV-infected people during the HAART era: a population-based study. AIDS. 2014;28:2313–8.

Article  CAS  PubMed  Google Scholar 

Orem J, Mbidde EK, Lambert B, de Sanjose S, Weiderpass E. Burkitt’s lymphoma in Africa, a review of the epidemiology and etiology. Afr Health Sci. 2007;7:166–75.

PubMed  PubMed Central  Google Scholar 

Simbayi L, Zuma K, Zungu N, Moyo S, Marinda E, Jooste S, et al. South African national HIV prevalence, incidence, behaviour and communication survey, 2017. Cape Town: HSRC Press; 2019.

Sengayi‐Muchengeti M, Singh E, Chen WC, Bradshaw D, de Villiers CB, Newton R, et al. Thirteen cancers associated with HIV infection in a Black South African cancer patient population (1995‐2016). Int J Cancer. 2023;152:183–94.

Article  PubMed  Google Scholar 

Wiggill T, Mayne E, Perner Y, Vaughan J. Changing patterns of lymphoma in the antiretroviral therapy era in Johannesburg, South Africa. J Acquir Immune Defic Syndr 2021;88:252–60.

Article  CAS  PubMed  Google Scholar 

Mburu W, Devesa SS, Check D, Shiels MS, Mbulaiteye SM. Incidence of Burkitt lymphoma in the United States during 2000 to 2019. Int J Cancer. 2023;153:1182–91.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singh E, Ruff P, Babb C, Sengayi M, Beery M, Khoali L, et al. Establishment of a cancer surveillance programme: the South African experience. Lancet Oncol. 2015;16:e414–21.

Article  PubMed  PubMed Central  Google Scholar 

Singh E, Underwood JM, Nattey C, Babb C, Sengayi M, Kellett P. South African National Cancer Registry: effect of withheld data from private health systems on cancer incidence estimates. South Afr Med J. 2015;105:107–9.

Article  CAS  Google Scholar 

Little RJA, Rubin DB. The analysis of social science data with missing values. Socio Methods Res. 1989;18:292–326.

Article  Google Scholar 

Statistics South Africa. Service standards. 2023. https://www.statssa.gov.za/?page_id=5365.

Johnson LF, Meyer-Rath G, Dorrington RE, Puren A, Seathlodi T, Zuma K, et al. The effect of HIV programs in South Africa on national HIV incidence trends, 2000-2019. J Acquir Immune Defic Syndr. 2022;90:115–23.

Article  PubMed  Google Scholar 

South African National Department of Health. National consolidated guidelines for the management of HIV in adults, adolescents, children and infants and of prevention of mother-to-child transmission. National Department of Health. 2020.

Doll R, Payne P, Waterhouse J. Cancer incidence in five continents: a technical report. Berlin: Spinger-Verlag (for UICC); 1966.

Statistics South Africa. General Household Survey 2010. Statistics South Africa 2011.

Mbulaiteye SM, Anderson WF, Ferlay J, Bhatia K, Chang C, Rosenberg PS, et al. Pediatric, elderly, and emerging adult-onset peaks in Burkitt’s lymphoma incidence diagnosed in four continents, excluding Africa. Am J Hematol. 2012;87:573–8.

Article  PubMed  PubMed Central  Google Scholar 

Karim QA, Karim SSA. The evolving HIV epidemic in South Africa. Int J Epidemiol. 2002;31:37–40.

Article  Google Scholar 

Karim SSA, Churchyard GJ, Karim QA, Lawn SD. HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response. Lancet. 2009;374:921–33.

Puvaneswaran B, Shoba B. Misdiagnosis of tuberculosis in patients with lymphoma. South Afr Med J. 2012;103:32.

Article  CAS  Google Scholar 

Dunford A, Weinstock DM, Savova V, Schumacher SE, Cleary JP, Yoda A, et al. Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias. Nat Genet. 2017;49:10–6.

Article  CAS  PubMed  Google Scholar 

Thomas N, Dreval K, Gerhard DS, Hilton LK, Abramson JS, Ambinder RF, et al. Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma. Blood. 2023;141:904–16.

Article  CAS  PubMed  Google Scholar 

Richter J, John K, Staiger AM, Rosenwald A, Kurz K, Michgehl U, et al. Epstein–Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features. Br J Haematol. 2022;196:681–9.

Article  CAS  PubMed  Google Scholar 

Wong IKJ, Grulich AE, Poynten IM, Polizzotto MN, van Leeuwen MT, Amin J, et al. Time trends in cancer incidence in Australian people living with HIV between 1982 and 2012. HIV Med. 2022;23:134–45.

Article  PubMed  Google Scholar 

Park LS, Tate JP, Sigel K, Rimland D, Crothers K, Gibert C, et al. Time trends in cancer incidence in persons living with HIV/AIDS in the antiretroviral therapy era: 1997-2012. AIDS. 2016;30:1795–806.

Article  CAS  PubMed  Google Scholar 

Majaya E, Girdler-Brown BV, Muchengeti M, Singh E. The impact of the South African antiretroviral treatment programme on the age-standardised incidence rate of Kaposi sarcoma, 1999–2016: an interrupted time series analysis. Int J Infect Dis. 2021;102:20–7.

Article  PubMed  Google Scholar 

Stuart KV, Shepherd DJ, Lombard A, Hollhumer R, Muchengeti M. Incidence and epidemiology of conjunctival squamous cell carcinoma in relation to the HIV epidemic in South Africa: a 25-year analysis of the National Cancer Registry (1994–2018). Br J Ophthalmol. 2022;108:175–80.

Eltom MA, Jemal A, Mbulaiteye SM, Devesa SS, Biggar RJ. Trends in Kaposi’s sarcoma and non-Hodgkin’s lymphoma incidence in the United States from 1973 through 1998. J Natl Cancer Inst. 2002;94:1204–10.

Article  PubMed  Google Scholar 

Wang Y, Shen Z, He C, Xing X, Tan Z, Sang W. Global, regional, and national burden of Burkitt lymphoma from 1990 to 2021 and predictions to 2030: a systematic analysis for the Global Burden of Disease Study 2021. Blood Cancer J. 2024;14:154.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES. The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood. 2011;117:5019–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TFE, et al. A biologic definition of Burkitt’s lymphoma from transcriptional and genomic profiling. N Engl J Med. 2006;354:2419–30.

Article  CAS  PubMed  Google Scholar 

Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma E-J, et al. Molecular diagnosis of Burkitt’s lymphoma. N Engl J Med. 2006;354:2431–42.

Article 

Comments (0)

No login
gif