US Preventive Services Task Force, Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, et al. Risk Assessment, genetic counseling, and genetic testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2019;322:652–65.

Article  Google Scholar 

Childers CP, Childers KK, Maggard-Gibbons M, Macinko J. National Estimates of Genetic Testing in Women with a history of breast or ovarian Cancer. J Clin Oncol. 2017;35:3800–6.

Article  PubMed  PubMed Central  Google Scholar 

Parente DJ. BRCA-Related Cancer Genetic Counseling is indicated in many women seeking primary care. J Am Board Fam Med. 2020;33:885–93.

Article  PubMed  Google Scholar 

Linfield DT, Rothberg MB, Pfoh ER, Noss R, Cassard L, Powers JC, et al. Primary care physician referral practices regarding BRCA1/2 genetic counseling in a major health system. Breast Cancer Res Treat. 2022;195:153–60.

Article  CAS  PubMed  Google Scholar 

Haverfield EV, Esplin ED, Aguilar SJ, Hatchell KE, Ormond KE, Hanson-Kahn A, et al. Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study. BMC Med. 2021;19:199.

Article  PubMed  PubMed Central  Google Scholar 

Daly MB, Pal T, Maxwell KN, Churpek J, Kohlmann W, AlHilli Z, et al. NCCN Guidelines® insights: Genetic/Familial High-Risk Assessment: breast, ovarian, and pancreatic, Version 2.2024. J Natl Compr Canc Netw. 2023;21:1000–10.

Article  CAS  PubMed  Google Scholar 

Domchek SM, Friebel TM, Singer CF, Evans DG, Lynch HT, Isaacs C, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA. 2010;304:967–75.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Buchanan AH, Manickam K, Meyer MN, Wagner JK, Hallquist MLG, Williams JL, et al. Correction to: early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants. Genet Med. 2021;23:2470.

Article  PubMed  PubMed Central  Google Scholar 

ASCO Releases Rapid Guideline Recommendation Update for Certain Patients With Hereditary Breast Cancer [Internet]. ASCO. 2021 [cited 2023 May 8]. https://old-prod.asco.org/about-asco/press-center/news-releases/asco-releases-rapid-guideline-recommendation-update-certain

Therkildsen C, Jensen LH, Rasmussen M, Bernstein I. An update on Immune Checkpoint Therapy for the treatment of Lynch Syndrome. Clin Exp Gastroenterol. 2021;14:181–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hereditary Cancer Syndromes and Risk Assessment. ACOG COMMITTEE OPINION SUMMARY, number 793. Obstet Gynecol. 2019;134:1366–7.

Article  Google Scholar 

U.S. Preventive Services Task Force. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: recommendation statement. Ann Intern Med. 2005;143:355–61.

Article  Google Scholar 

Hampel H, Bennett RL, Buchanan A, Pearlman R, Wiesner GL, Guideline Development Group, American College of Medical Genetics and Genomics Professional Practice and Guidelines Committee and National Society of Genetic Counselors Practice Guidelines Committee. A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. Genet Med. 2015;17:70–87.

Article  PubMed  Google Scholar 

Katz SJ, Ward KC, Hamilton AS, Mcleod MC, Wallner LP, Morrow M, et al. Gaps in receipt of clinically indicated genetic Counseling after diagnosis of breast Cancer. J Clin Oncol. 2018;36:1218–24.

Article  PubMed  PubMed Central  Google Scholar 

Kurian AW, Ward KC, Abrahamse P, Bondarenko I, Hamilton AS, Deapen D, et al. Time trends in receipt of Germline Genetic Testing and results for women diagnosed with breast Cancer or ovarian Cancer, 2012–2019. J Clin Oncol. 2021;39:1631–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kurian AW, Abrahamse P, Furgal A, Ward KC, Hamilton AS, Hodan R, et al. Germline Genetic Test after Cancer Diagnosis JAMA. 2023;330:43–51.

CAS  PubMed  Google Scholar 

Chun DS, Berse B, Venne VL, DuVall SL, Filipski KK, Kelley MJ, et al. BRCA testing within the Department of Veterans affairs: concordance with clinical practice guidelines. Fam Cancer. 2017;16:41–9.

Article  PubMed  Google Scholar 

Harding B, Webber C, Ruhland L, Dalgarno N, Armour CM, Birtwhistle R, et al. Primary care providers’ lived experiences of genetics in practice. J Community Genet. 2019;10:85–93.

Article  PubMed  Google Scholar 

Evenson SA, Hoyme HE, Haugen-Rogers JE, Larson EA, Puumala SE. Patient and physician perceptions of genetic testing in primary care. S D Med. 2016;69:487–93.

PubMed  Google Scholar 

Bombard Y, Ginsburg GS, Sturm AC, Zhou AY, Lemke AA. Digital health-enabled genomics: opportunities and challenges. Am J Hum Genet. 2022;109:1190–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dusic EJ, Theoryn T, Wang C, Swisher EM, Bowen DJ, EDGE Study Team. Barriers, interventions, and recommendations: improving the genetic testing landscape. Front Digit Health. 2022;4:961128.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Son Y, Lim MC, Seo SS, Kang S, Park SY. Completeness of pedigree and family cancer history for ovarian cancer patients. J Gynecol Oncol. 2014;25:342–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arun BK, Peterson SK, Sweeney LE, Bluebond RD, Tidwell RSS, Makhnoon S, et al. Increasing referral of at-risk women for genetic counseling and BRCA testing using a screening tool in a community breast imaging center. Cancer. 2021;128:94–102.

Article  PubMed  Google Scholar 

Shore ND, Lenz L, Flake DD, Meek S, Davis T, Copeland K, et al. Hereditary cancer risk assessment in the community urology practice setting. J Clin Orthod. 2022;40:278–278.

Google Scholar 

Hessock M, Brewer T, Hutson S, Anderson J. Use of a standardized Tool to identify women at risk for Hereditary breast and ovarian. Nurs Womens Health. 2021;25:187–97.

Article  PubMed  Google Scholar 

Rao SK, Thomas KA, Singh R, Biltibo E, Lammers PE, Wiesner GL. Increased ease of access to genetic counseling for low-income women with breast cancer using a point of care screening tool. J Community Genet. 2021;12:129–36.

Article  PubMed  PubMed Central  Google Scholar 

Nazareth S, Hayward L, Simmons E, Snir M, Hatchell KE, Rojahn S, et al. Hereditary Cancer Risk using a genetic Chatbot before Routine Care visits. Obstet Gynecol. 2021;138:860–70.

PubMed  PubMed Central  Google Scholar 

Bucheit L, Johansen Taber K, Ready K. Validation of a digital identification tool for individuals at risk for hereditary cancer syndromes. Hered Cancer Clin Pract. 2019;17:2.

Article  PubMed  PubMed Central  Google Scholar 

Wu RR, Myers RA, Neuner J, McCarty C, Haller IV, Harry M, et al. Implementation-effectiveness trial of systematic family health history based risk assessment and impact on clinical disease prevention and surveillance activities. BMC Health Serv Res. 2022;22:1486.

Article  PubMed  PubMed Central  Google Scholar 

Cohn WF, Ropka ME, Pelletier SL, Barrett JR, Kinzie MB, Harrison MB, et al. Health Heritage© a web-based tool for the collection and assessment of family health history: initial user experience and analytic validity. Public Health Genomics. 2010;13:477–91.

Article  CAS  PubMed  Google Scholar 

Shi J, Morgan KL, Bradshaw RL, Jung S-H, Kohlmann W, Kaphingst KA, et al. Identifying patients who meet Criteria for Genetic Testing of Hereditary Cancers based on structured and Unstructured Family Health History Data in the Electronic Health Record: Natural Language Processing Approach. JMIR Med Inf. 2022;10:e37842.

Article  Google Scholar 

Henderson V, Ganschow P, Wang C, Hoskins KF. Population screening to identify women at risk for hereditary breast cancer syndromes: the path forward or the road not taken? Cancer. 2022;128:30–3.

Article  PubMed  Google Scholar 

Nazareth S, Nussbaum RL, Siglen E, Wicklund CA. Chatbots & artificial intelligence to scale genetic information delivery. J Genet Couns. 2021;30:7–10.

Article  PubMed  Google Scholar 

Smith C, Caleshu C, Bonadies D, Denton JJ. Use of digital health tools with point-of-care testing improves acce