LncRNA XIST/miR-455-3p/HOXC4 axis promotes breast cancer development by activating TGF-β/SMAD signaling pathway

Ahmadpour ST, Orre C, Bertevello PS, Mirebeau-Prunier D, Dumas JF, Desquiret-Dumas V (2023) Breast Cancer Chemoresistance: insights into the Regulatory Role of lncRNA. Int J Mol Sci 24. https://doi.org/10.3390/ijms242115897

Akrida I, Mulita F, Plachouri KM, Benetatos N, Maroulis I, Papadaki H (2023) Epithelial to mesenchymal transition (EMT) in metaplastic breast cancer and phyllodes breast tumors. Med Oncol (Northwood Lond Engl) 41:20. https://doi.org/10.1007/s12032-023-02259-4

Article  CAS  Google Scholar 

Alsadi N, Yasavoli-Sharahi H, Mueller R, Cuenin C, Chung F, Herceg Z, Matar C (2023) Protective mechanisms of Polyphenol-Enriched Blueberry Preparation in preventing inflammation in the skin against UVB-Induced damage in an animal model. Antioxid (Basel Switzerland) 13. https://doi.org/10.3390/antiox13010025

Azizidoost S, Ghaedrahmati F, Sheykhi-Sabzehpoush M, Uddin S, Ghafourian M, Mousavi Salehi A, Keivan M, Cheraghzadeh M, Nazeri Z, Farzaneh M, Khoshnam SE (2023) The role of LncRNA MCM3AP-AS1 in human cancer. Clin Translational Oncology: Official Publication Federation Span Oncol Soc Natl Cancer Inst Mexico 25:33–47. https://doi.org/10.1007/s12094-022-02904-w

Article  CAS  Google Scholar 

Baljon KJ, Ramaiah P, Saleh EAM, Al-Dolaimy F, Al-Dami FH, Gandla K, Alkhafaji AT, Abbas AHR, Alsaalamy AH, Bisht YS (2023) LncRNA PVT1: as a therapeutic target for breast cancer. Pathol Res Pract 248:154675. https://doi.org/10.1016/j.prp.2023.154675

Article  CAS  PubMed  Google Scholar 

Casalino L, Talotta F, Matino I, Verde P (2023) FRA-1 as a Regulator of EMT and metastasis in breast Cancer. Int J Mol Sci 24. https://doi.org/10.3390/ijms24098307

de Bessa Garcia SA, Araújo M, Pereira T, Mouta J, Freitas R (2020) HOX genes function in breast Cancer development. Biochim et Biophys acta Reviews cancer 1873:188358. https://doi.org/10.1016/j.bbcan.2020.188358

Article  CAS  Google Scholar 

Drabsch Y, ten Dijke P (2011) TGF-β signaling in breast cancer cell invasion and bone metastasis. J Mammary Gland Biol Neoplasia 16:97–108. https://doi.org/10.1007/s10911-011-9217-1

Article  PubMed  PubMed Central  Google Scholar 

Fahad Ullah M (2019) Breast Cancer: current perspectives on the Disease Status. Adv Exp Med Biol 1152:51–64. https://doi.org/10.1007/978-3-030-20301-6_4

Article  CAS  PubMed  Google Scholar 

Fan C, Wang Q, Kuipers TB, Cats D, Iyengar PV, Hagenaars SC, Mesker WE, Devilee P, Tollenaar R, Mei H, Ten Dijke P (2023a) LncRNA LITATS1 suppresses TGF-β-induced EMT and cancer cell plasticity by potentiating TβRI degradation. EMBO J 42:e112806. https://doi.org/10.15252/embj.2022112806

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan C, González-Prieto R, Kuipers TB, Vertegaal ACO, van Veelen PA, Mei H, Ten Dijke P (2023b) The lncRNA LETS1 promotes TGF-β-induced EMT and cancer cell migration by transcriptionally activating a TβR1-stabilizing mechanism. Sci Signal 16:eadf1947. https://doi.org/10.1126/scisignal.adf1947

Article  CAS  PubMed  Google Scholar 

Fang J, Huang C, Ke J, Li J, Zhang W, Xue H, Chen J (2020) lncRNA TTN-AS1 facilitates proliferation, invasion, and epithelial-mesenchymal transition of breast cancer cells by regulating miR-139-5p/ZEB1 axis. J Cell Biochem 121:4772–4784. https://doi.org/10.1002/jcb.29700

Article  CAS  PubMed  Google Scholar 

Farzaneh M, Nasrolahi A, Ghaedrahmati F, Masoodi T, Najafi S, Sheykhi-Sabzehpoush M, Dari MAG, Radoszkiewicz K, Uddin S, Azizidoost S, Khoshnam SE (2023) Potential roles of lncRNA-XIST/miRNAs/mRNAs in human cancer cells. Clin Translational Oncology: Official Publication Federation Span Oncol Soc Natl Cancer Inst Mexico 25:2015–2042. https://doi.org/10.1007/s12094-023-03110-y

Article  CAS  Google Scholar 

Feng J, Zhang J, Li Y, Cheng W, Liu Y, Chen Z, Duan Y, Yu T, Hu A, Wang T, Zhang H, Li M, Rong Z, Ma F, Guo B (2023) Inhibition of lncRNA PCAT19 promotes breast cancer proliferation. Cancer Med 12:11971–11982. https://doi.org/10.1002/cam4.5872

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX (2020) Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways. Acta Pharmacol Sin 41:670–677. https://doi.org/10.1038/s41401-019-0324-7

Article  CAS  PubMed  Google Scholar 

Ghafouri-Fard S, Esmaeili M, Taheri M (2020) H19 lncRNA: roles in tumorigenesis. Biomed Pharmacotherapy = Biomedecine Pharmacotherapie 123:109774. https://doi.org/10.1016/j.biopha.2019.109774

Article  CAS  Google Scholar 

Guo J, Liu C, Wang W, Liu Y, He H, Chen C, Xiang R, Luo Y (2018) Identification of serum mir-1915-3p and mir-455-3p as biomarkers for breast cancer. PLoS ONE 13:e0200716. https://doi.org/10.1371/journal.pone.0200716

Article  CAS  PubMed  PubMed Central  Google Scholar 

He CP, Jiang XC, Chen C, Zhang HB, Cao WD, Wu Q, Ma C (2021) The function of lncRNAs in the pathogenesis of osteoarthritis. Bone Joint Res 10:122–133. https://doi.org/10.1302/2046-3758.102.Bjr-2020-0228.R1

Article  PubMed  PubMed Central  Google Scholar 

He C, Liu Y, Li J, Zheng X, Liang J, Cui G, Chang H (2022) LncRNA RPSAP52 promotes cell proliferation and inhibits cell apoptosis via modulating miR-665/STAT3 in gastric cancer. Bioengineered 13:8699–8711. https://doi.org/10.1080/21655979.2022.2054754

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hua G, Zeng ZL, Shi YT, Chen W, He LF, Zhao GF (2021) LncRNA XIST contributes to Cisplatin Resistance of Lung Cancer cells by promoting Cellular Glycolysis through Sponging miR-101-3p. Pharmacology 106:498–508. https://doi.org/10.1159/000512621

Article  CAS  PubMed  Google Scholar 

Huang Q, Wu L, Wang Y, Kong X, Xiao X, Huang Q, Li M, Zhai Y, Shi F, Zhao R, Zhong J, Xiong L (2022) Caveolin-1-deficient fibroblasts promote migration, invasion, and stemness via activating the TGF-β/Smad signaling pathway in breast cancer cells. Acta Biochim Biophys Sin 54:1587–1598. https://doi.org/10.3724/abbs.2022150

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Z, Zhen S, Jin L, Chen J, Han Y, Lei W, Zhang F (2023a) miRNA-1260b promotes breast Cancer Cell Migration and Invasion by Downregulating CCDC134. Curr Gene Ther 23:60–71. https://doi.org/10.2174/1566523222666220901112314

Article  CAS  PubMed  Google Scholar 

Huang X, Jia Z, Li X, Hu Z, Yu X, Xia J (2023b) Asiaticoside hampers epithelial-mesenchymal transition by promoting PPARG expression and suppressing P2RX7-mediated TGF-β/Smad signaling in triple-negative breast cancer. Phytother Res 37:1771–1786. https://doi.org/10.1002/ptr.7692

Article  CAS  PubMed  Google Scholar 

Hur H, Lee JY, Yun HJ, Park BW, Kim MH (2014) Analysis of HOX gene expression patterns in human breast cancer. Mol Biotechnol 56:64–71. https://doi.org/10.1007/s12033-013-9682-4

Article  CAS  PubMed  Google Scholar 

Ji X, Tian X, Feng S, Zhang L, Wang J, Guo R, Zhu Y, Yu X, Zhang Y, Du H, Zablotskii V, Zhang X (2023) Intermittent F-actin perturbations by magnetic fields inhibit breast Cancer metastasis. Res (Washington DC) 6:0080. https://doi.org/10.34133/research.0080

Article  CAS  Google Scholar 

Katsura C, Ogunmwonyi I, Kankam HK, Saha S (2022) Breast cancer: presentation, investigation and management. British journal of hospital medicine (London, England: 2005) 83:1–7. https://doi.org/10.12968/hmed.2021.0459

Lei S, Zheng R, Zhang S, Wang S, Chen R, Sun K, Zeng H, Zhou J, Wei W (2021) Global patterns of breast cancer incidence and mortality: a population-based cancer registry data analysis from 2000 to 2020. Cancer Commun (London England) 41:1183–1194. https://doi.org/10.1002/cac2.12207

Article  Google Scholar 

Li X, Li Y, Yu X, Jin F (2020) Identification and validation of stemness-related lncRNA prognostic signature for breast cancer. J Translational Med 18:331. https://doi.org/10.1186/s12967-020-02497-4

Article  CAS  Google Scholar 

Li N, Chen XJ, Zeng YH, Zeng LP, Hu K, Chen LJ (2022a) Silencing of lncRNA CRNDE attenuates nonsmall-cell lung cancer progression by mediating the miR-455-3p/HDAC2 axis. Kaohsiung J Med Sci 38:749–760. https://doi.org/10.1002/kjm2.12558

Article  CAS  PubMed  Google Scholar 

Li Z, Li M, Xia P, Wang L, Lu Z (2022b) Targeting long non-coding RNA PVT1/TGF-β/Smad by p53 prevents glioma progression. Cancer Biol Ther 23:225–233. https://doi.org/10.1080/15384047.2022.2042160

Article  CAS  PubMed  PubMed Central 

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