Topical vancomycin powder for the prevention of surgical site infections in spinal deformity surgery: a systematic review and meta-analysis

Zhou J et al (2020) Incidence of surgical site infection after spine surgery: a systematic review and meta-analysis. Spine 45(3):208–216

Article  PubMed  Google Scholar 

Li Y, Glotzbecker M, Hedequist D (2012) Surgical site infection after pediatric spinal deformity surgery. Curr Rev Musculoskelet Med 5(2):111–119

Article  PubMed  PubMed Central  Google Scholar 

Warner SJ et al (2017) Epidemiology of deep surgical site infections after pediatric spinal fusion surgery. Spine 42(3):E163-e168

Article  PubMed  Google Scholar 

Hedequist D et al (2009) Failure of attempted implant retention in spinal deformity delayed surgical site infections. Spine 34(1):60–64

Article  PubMed  Google Scholar 

Di Silvestre M et al (2011) Late-developing infection following posterior fusion for adolescent idiopathic scoliosis. Eur Spine J 20:121–127

Article  PubMed Central  Google Scholar 

Anderson PA et al (2017) Prevention of surgical site infection in spine surgery. Neurosurgery 80(3s):S114-s123

Article  PubMed  Google Scholar 

Olsen MA et al (2008) Risk factors for surgical site infection following orthopaedic spinal operations. J Bone Joint Surg Am 90(1):62–69

Article  PubMed  Google Scholar 

Xing D et al (2013) A methodological, systematic review of evidence-based independent risk factors for surgical site infections after spinal surgery. Eur Spine J 22(3):605–615

Article  PubMed  Google Scholar 

Rudic TN et al (2023) Surgical Site infection after primary spinal fusion surgery for adolescent idiopathic scoliosis: An analysis of risk factors from a nationwide insurance database. Spine 48(8):e101–e106

PubMed  Google Scholar 

Wang M et al (2022) Incidence, management and outcome of delayed deep surgical site infection following spinal deformity surgery: 20-year experience at a single institution. Global Spine J 12(6):1141–1150

Article  PubMed  Google Scholar 

Haller JM et al (2019) Intrawound vancomycin powder associated with reduced surgical site infection in rib-based distraction surgery. J Pediatr Orthop 39(9):e703–e707

Article  PubMed  Google Scholar 

van Herwijnen B et al (2016) An intraoperative irrigation regimen to reduce the surgical site infection rate following adolescent idiopathic scoliosis surgery. Ann R Coll Surg Engl 98(5):320–323

Article  PubMed  PubMed Central  Google Scholar 

van Rhee MA, de Klerk LW, Verhaar JA (2007) Vacuum-assisted wound closure of deep infections after instrumented spinal fusion in six children with neuromuscular scoliosis. Spine J 7(5):596–600

Article  PubMed  Google Scholar 

Barker Ii FG et al (2002) Efficacy of prophylactic antibiotic therapy in spinal surgery: a meta-analysis. Neurosurgery 51(2):391–401

Article  Google Scholar 

Watters WC et al (2009) Antibiotic prophylaxis in spine surgery: an evidence-based clinical guideline for the use of prophylactic antibiotics in spine surgery. Spine J 9(2):142–146

Article  PubMed  Google Scholar 

Chiang H-Y et al (2014) Effectiveness of local vancomycin powder to decrease surgical site infections: a meta-analysis. Spine J 14(3):397–407

Article  PubMed  Google Scholar 

Lemans JVC et al (2019) Intrawound treatment for prevention of surgical site infections in instrumented spinal surgery: a systematic comparative effectiveness review and meta-analysis. Glob Spine J 9(2):219–230

Article  Google Scholar 

Sathish M, Girinivasan C (2021) Is use of topical vancomycin in pediatric spine surgeries a safe option in the prevention of surgical site infections? A meta-analysis and systematic review of the literature. Glob Spine J 11(5):774–781

Article  Google Scholar 

Armaghani SJ et al (2014) Safety of topical vancomycin for pediatric spinal deformity: nontoxic serum levels with supratherapeutic drain levels. Spine 39(20):1683–1687

Article  PubMed  Google Scholar 

Li S et al (2019) Meta-analysis of topical vancomycin powder for microbial profile in spinal surgical site infections. Eur Spine J 28(12):2972–2980

Article  PubMed  Google Scholar 

Luo H et al (2022) Intraoperative vancomycin powder to reduce surgical site infections after posterior spine surgery: a systematic review and meta-analysis. EFORT Open Rev 7(2):109–121

Article  PubMed  PubMed Central  Google Scholar 

Shaffer A et al (2023) Perioperative prophylaxis for surgical site infections in pediatric spinal surgery: a systematic review and network meta-analysis. J Neurosurg Pediatr 31(1):43–51

Article  PubMed  Google Scholar 

Rocos B et al (2023) Antibiotic use in adult spine deformity surgery: results from the AO spine surveillance of the management of patients with adult spine deformity. Glob Spine J. https://doi.org/10.1177/21925682231201240

Article  Google Scholar 

Shu L et al (2023) Prophylactic application of vancomycin powder in preventing surgical site infections after spinal surgery. World Neurosurg 171:e542–e553

Article  PubMed  Google Scholar 

Mallet C et al (2022) Does the use of intrawound povidone-iodine irrigation and local vancomycin powder impact surgical site infection rate in adolescent idiopathic scoliosis surgery? Eur Spine J 31(11):3020–3028

Article  PubMed  Google Scholar 

Roberto RF et al (2021) Povidone-iodine irrigation combined with Vancomycin powder lowers infection rates in pediatric deformity surgery. Spine Deform 9(5):1315–1321

Article  PubMed  PubMed Central  Google Scholar 

Shinohara K et al (2024) Intrawound vancomycin powder reduces delayed deep surgical site infections following posterior spinal fusion for adolescent idiopathic scoliosis. Spine. https://doi.org/10.1097/BRS.0000000000004980

Article  PubMed  Google Scholar 

Theologis AA et al (2014) Local intrawound vancomycin powder decreases the risk of surgical site infections in complex adult deformity reconstruction: a cost analysis. Spine 39(22):1875–1880

Article  PubMed  Google Scholar 

Thompson GH et al (2018) Does vancomycin powder decrease surgical site infections in growing spine surgery?: a preliminary study. J Bone Joint Surg Am 100(6):466–471

Article  PubMed  Google Scholar 

Meza BC, Talwar D, Flynn JM (2020) Measures to reduce end-of-case wound contamination: the impact of intra-wound vancomycin powder and betadine irrigation on surgical site infections in posterior spinal fusion. Spine Deform 8(1):45–50

Article  PubMed  Google Scholar 

Martin JR et al (2014) Experience with intrawound vancomycin powder for spinal deformity surgery. Spine 39(2):177–184

Article  PubMed  Google Scholar 

Liu N et al (2015) Comparison of intrawound vancomycin utility in posterior instrumented spine surgeries between patients with tumor and nontumor patients. Spine 40(20):1586–1592

Article  PubMed  Google Scholar 

Horan TC et al (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13(10):606–608

Article  CAS  PubMed  Google Scholar 

Wang X et al (2023) Surgical site infection in spinal surgery: a bibliometric analysis. J Orthop Surg Res 18(1):337

Article  PubMed  PubMed Central  Google Scholar 

Flynn JM et al (2013) VEPTR to treat nonsyndromic congenital scoliosis: a multicenter, mid-term follow-up study. J Pediatr Orthop 33(7):679–684

Article  PubMed  Google Scholar 

Garg S et al (2014) Wound complications of vertical expandable prosthetic titanium rib incisions. Spine 39(13):E777–E781

Article  PubMed 

Comments (0)

No login
gif