Anti-inflammatory potential of aconitine produced by endophytic fungus Acremonium alternatum

Aidoo DB, Konja D, Henneh IT, Ekor M (2021) Protective effect of bergapten against human erythrocyte hemolysis and protein denaturation in vitro. Int J Inflam 2021:1–7. https://doi.org/10.1155/2021/1279359

Article  CAS  Google Scholar 

Akhtar MF, Khan K, Saleem A et al (2021) Chemical characterization and anti-arthritic appraisal of Monotheca Buxifolia methanolic extract in complete Freund’s adjuvant-induced arthritis in Wistar rats. Inflammopharmacology 29:393–408. https://doi.org/10.1007/s10787-020-00783-7

Article  CAS  PubMed  Google Scholar 

Al-Lamki RS, Wang J, Skepper JN et al (2001) Expression of tumor necrosis factor receptors in normal kidney and rejecting renal transplants. Lab Investig 81:1503–1515. https://doi.org/10.1038/labinvest.3780364

Article  CAS  PubMed  Google Scholar 

Alam A, Khan AA (2020) Argemone mexicana L.: a weed with versatile medicinal and pharmacological applications. Ann Phytomedicine Int J. https://doi.org/10.21276/ap.2020.9.1.29. 9:

Article  Google Scholar 

Alam MB, Hossain MS, Haque ME (2011) Antioxidant and anti-inflammatory activities of the leaf extract of Brassica nigra. Int J Pharm Sci Res 2:303–310

Google Scholar 

Ali MF, Mahmud S, Mohiuddin RB et al (2023) Screening of preliminary phytochemicals, molecular identification, and antimicrobial and anti-inflammatory activity of Justicia Gendarussa. Evidence-Based Complement Altern Med 2023:1–8. https://doi.org/10.1155/2023/6885353

Article  Google Scholar 

Allen GC, Flores-Vergara MA, Krasynanski S et al (2006) A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide. Nat Protoc 1:2320–2325. https://doi.org/10.1038/nprot.2006.384

Article  CAS  PubMed  Google Scholar 

Ananthi T, Chitra M (2013) Screening of invitro anti-inflammatory activity of Michelia Champaca Linn. Flowers. Asian J Pharm Clin Res 6:1–15

Google Scholar 

Asif HM, Zafar F, Ahmad K et al (2023) Synthesis, characterization and evaluation of anti-arthritic and anti-inflammatory potential of curcumin loaded chitosan nanoparticles. Sci Rep 13:10274. https://doi.org/10.1038/s41598-023-37152-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Badavenkatappa GS, Nelson VK, Peraman R (2023) Tinospora Sinensis(Lour.) Merr alkaloid rich extract induces colon cancer cell death via ROS mediated, mTOR dependent apoptosis pathway: an in-vitro study. BMC Complement Med Ther 23:33. https://doi.org/10.1186/s12906-023-03849-5

Article  CAS  Google Scholar 

Bandgar BP, Patil SA, Gacche RN et al (2010) Synthesis and biological evaluation of nitrogen-containing chalcones as possible anti-inflammatory and antioxidant agents. Bioorg Med Chem Lett 20:730–733. https://doi.org/10.1016/j.bmcl.2009.11.068

Article  CAS  PubMed  Google Scholar 

Bowerbank SL, Gallidabino MD, Dean JR (2022) Plant poisons in the garden: a human risk management. Separations 9:308. https://doi.org/10.3390/separations9100308

Article  CAS  Google Scholar 

Bukhari IA, Pivac N, Alhumayyd MS et al (2013) The analgesic and anticonvulsant effects of piperine in mice. J Physiol Pharmacol 64:789–794

CAS  PubMed  Google Scholar 

Chaitanya RS, Sandhya S et al (2011) HRBC membrane stabilizing property of root, stem and leaf of Glochidion Velutinum. Int J Rsearch Pharamaceutical Biomed Sci 2:256–259

Google Scholar 

Chan KY, Mohamad K, Ooi AJA et al (2012) Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton Polyandrus Merr. Fitoterapia 83:961–967. https://doi.org/10.1016/j.fitote.2012.04.018

Article  CAS  PubMed  Google Scholar 

Chen Y, Zhang L, Zou G et al (2020) Anti-inflammatory activities of alkaloids from the mangrove endophytic fungus phomopsis sp SYSUQYP-23. Bioorg Chem 97:103712. https://doi.org/10.1016/j.bioorg.2020.103712

Article  CAS  PubMed  Google Scholar 

Deng J, Han J, Chen J et al (2021) Comparison of analgesic activities of aconitine in different mice pain models. PLoS ONE 16:e0249276. https://doi.org/10.1371/journal.pone.0249276

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deng L, He S, Guo N et al (2023) Molecular mechanisms of ferroptosis and relevance to inflammation. Inflamm Res 72:281–299. https://doi.org/10.1007/s00011-022-01672-1

Article  CAS  PubMed  Google Scholar 

Dey P, Kundu A, Kumar A et al (2020) Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids). Recent advances in Natural products Analysis. Elsevier, pp 505–567

dos Reis JBA, Lorenzi AS, do Vale HMM (2022) Methods used for the study of endophytic fungi: a review on methodologies and challenges, and associated tips. Arch Microbiol 204:675. https://doi.org/10.1007/s00203-022-03283-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elawady ME, Hamed AA, Alsallami WM et al (2023) Bioactive metabolite from endophytic Aspergillus versicolor SB5 with anti-acetylcholinesterase, anti-inflammatory and antioxidant activities: in vitro and in silico studies. Microorganisms 11:1062. https://doi.org/10.3390/microorganisms11041062

Elghaffar RYA, Amin BH, Hashem AH et al (2022) Promising endophytic Alternaria alternata from leaves of Ziziphus spina-christi: phytochemical analyses, antimicrobial and antioxidant activities. Appl Biochem Biotechnol 194:3984–4001. https://doi.org/10.1007/s12010-022-03959-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fadhil S, Reza MH, Rouhollah G, Reza VRM (2008) Spectrophotometric determination of total alkaloids in Peganum harmala L. using bromocresol green. Res J Phytochem 675

Félix-Silva J, Souza T, Camara RBBG et al (2014) In vitro anticoagulant and antioxidant activities of Jatropha gossypiifolia L. (Euphorbiaceae) leaves aiming therapeutical applications. BMC Complement Altern Med 14:405. https://doi.org/10.1186/1472-6882-14-405

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fibrich B, Gao X, Puri A et al (2020) In vitro antioxidant, anti-inflammatory and skin permeation of Myrsine africana and its isolated compound myrsinoside B. Front Pharmacol 10. https://doi.org/10.3389/fphar.2019.01410

Gao Y, Fan H, Nie A et al (2022) Aconitine: a review of its pharmacokinetics, pharmacology, toxicology and detoxification. J Ethnopharmacol 293:115270. https://doi.org/10.1016/j.jep.2022.115270

Article  CAS  PubMed  Google Scholar 

Graz B, Willcox ML, Diakite C et al (2010) Argemone mexicana decoction versus artesunate-amodiaquine for the management of malaria in Mali: policy and public-health implications. Trans R Soc Trop Med Hyg 104:33–41. https://doi.org/10.1016/j.trstmh.2009.07.005

Article  CAS  PubMed  Google Scholar 

Guo C, He L, Hu N et al (2022) Aconiti Lateralis Radix Praeparata lipid-soluble alkaloids alleviates IL-1β-induced inflammation of human fibroblast-like synoviocytes in rheumatoid arthritis by inhibiting NF-κB and MAPKs signaling pathways and inducing apoptosis. Cytokine 151:155809. https://doi.org/10.1016/j.cyto.2022.155809

Article  CAS  PubMed  Google Scholar 

Haeggström JZ, Newcomer ME (2023) Structures of leukotriene biosynthetic enzymes and development of new therapeutics. Annu Rev Pharmacol Toxicol 63:407–428. https://doi.org/10.1146/annurev-pharmtox-051921-085014

Article  CAS  PubMed  Google Scholar 

Hagel JM, Facchini PJ (2013) Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world. Plant Cell Physiol 54:647–672. https://doi.org/10.1093/pcp/pct020

Article  CAS  PubMed  Google Scholar 

Hortelano S, Través PG, Zeini M et al (2003) Sustained nitric oxide delivery delays nitric oxide-dependent apoptosis in macrophages: contribution to the physiological function of activated macrophages. J Immunol 171:6059–6064. https://doi.org/10.4049/jimmunol.171.11.6059

Article  CAS  PubMed  Google Scholar 

Jablonski JE, Schlesser JE, Mariappagoudar P (2006) HPLC-UV method for nicotine, strychnine, and aconitine in dairy products. J Agric Food Chem 54:7460–7465. https://doi.org/10.1021/jf061115a

Article  CAS  PubMed  Google Scholar 

Jacob J, Babu BM, Mohan MC et al (2018) Inhibition of proinflammatory pathways by bioactive fraction of Tinospora cordifolia. Inflammopharmacology 26:531–538. https://doi.org/10.1007/s10787-017-0319-2

Article  CAS  PubMed 

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