Angori S, Lobo J, Moch H (2022) Papillary renal cell carcinoma: current and controversial issues. Curr Opin Urol 32(4):344–351. https://doi.org/10.1097/MOU.0000000000001000
Article PubMed PubMed Central Google Scholar
Williamson SR, Hartmann A, Hes O et al (2022) Papillary renal cell carcinoma. In: WHO classification of tumours editorial board. Urinary and male genital tumours, vol 8, 5th edn. International Agency for Research on Cancer, Lyon (France), pp 47–49 https://publications.iarc.fr/610
Mancilla-Jimenez R, Stanley RJ, Blath RA (1976) Papillary renal cell carcinoma: a clinical, radiologic, and pathologic study of 34 cases. Cancer 38:2469–2480. https://doi.org/10.1002/1097-0142(197612)38:6<2469::aid-cncr2820380636>3.0.co;2-r
Article CAS PubMed Google Scholar
Delahunt B, Eble JN (1997) Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol 10:537–544
Mejean A, Hopirtean V, Bazin JP et al (2003) Prognostic factors for the survival of patients with papillary renal cell carcinoma: meaning of histological typing and multifocality. J Urol 170(3):764–767. https://doi.org/10.1097/01.ju.0000081122.57148.ec
Allory Y, Ouazana D, Boucher E et al (2003) Papillary renal cell carcinoma. Prognostic value of morphological subtypes in a clinicopathologic study of 43 cases. Virchows Arch 442(4):336–342. https://doi.org/10.1007/s00428-003-0787-1
Delahunt B, Eble JN, McCredie MR et al (2001) Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases. Hum Pathol 32(6):590–595. https://doi.org/10.1053/hupa.2001.24984
Article CAS PubMed Google Scholar
Klatte T, Pantuck AJ, Said JW et al (2009) Cytogenetic and molecular tumor profiling for type 1 and type 2 papillary renal cell carcinoma. Clin Cancer Res 15(4):1162–1169. https://doi.org/10.1158/1078-0432.CCR-08-1229
Article CAS PubMed Google Scholar
Sukov WR, Lohse CM, Leibovich BC et al (2012) Clinical and pathological features associated with prognosis in patients with papillary renal cell carcinoma. J Urol 187(1):54–59. https://doi.org/10.1016/j.juro.2011.09.053
Le X, Wang X-B, Zhao H et al (2020) Comparison of clinicopathologic parameters and oncologic outcomes between type 1 and type 2 papillary renal cell carcinoma. BMC Urol 20(1):148. https://doi.org/10.1186/s12894-020-00716-0
Article CAS PubMed PubMed Central Google Scholar
Polifka I, Agaimy A, Herrmann E et al (2019) High proliferation rate and TNM stage but not histomorphological subtype are independent prognostic markers for overall survival in papillary renal cell carcinoma. Hum Pathol 83:212–223. https://doi.org/10.1016/j.humpath.2018.08.006
Article CAS PubMed Google Scholar
Linehan WM, Spellman P, Ricketts C et al (2016) Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med 374(2):135–145. https://doi.org/10.1056/NEJMoa1505917
Article CAS PubMed Google Scholar
Chevarie-Davis M, Riazalhosseini Y, Arseneault M et al (2014) The morphologic and immunohistochemical spectrum of papillary renal cell carcinoma: study including 132 cases with pure type 1 and type 2 morphology as well as tumors with overlapping features. Am J Surg Pathol 38(7):887–894. https://doi.org/10.1097/PAS.0000000000000247
Saleeb RM, Plant P, Tawedrous E et al (2018) Integrated phenotypic/genotypic analysis of papillary renal cell carcinoma subtypes: identification of prognostic markers, cancer-related pathways, and implications for therapy. Eur Urol Focus 4(5):740–748. https://doi.org/10.1016/j.euf.2016.09.002
Saleeb RM, Brimo F, Farag M et al (2017) Toward biological subtyping of papillary renal cell carcinoma with clinical implications through histologic, immunohistochemical, and molecular analysis. Am J Surg Pathol 41(12):1618–1629. https://doi.org/10.1097/PAS.0000000000000962
Murugan P, Jia L, Dinatale RG et al (2022) Papillary renal cell carcinoma: a single institutional study of 199 cases addressing classification, clinicopathologic and molecular features, and treatment outcome. Mod Pathol 35(6):825–835. https://doi.org/10.1038/s41379-021-00990-9
Article CAS PubMed Google Scholar
Yang C, Shuch B, Kluger H et al (2020) High WHO/ISUP grade and unfavorable architecture, rather than typing of papillary renal cell carcinoma, may be associated with worse prognosis. Am J Surg Pathol 44:582–593. https://doi.org/10.1097/PAS.0000000000001455
Xiong S, Zhu W, Li X et al (2021) Whether histologic subtyping affect the oncological outcomes of patients with papillary renal cell carcinoma: evidence from a systematic review and meta-analysis. Transl Androl Urol 10(8):3255–3266. https://doi.org/10.21037/tau-21-329
Article PubMed PubMed Central Google Scholar
Pignot G, Elie C, Conquy S et al (2007) Survival analysis of 130 patients with papillary renal cell carcinoma: prognostic utility of type 1 and type 2 subclassification. Urology 69(2):230–235. https://doi.org/10.1016/j.urology.2006.09.052
Trpkov K, Hes O, Williamson SR et al (2021) New developments in existing WHO entities and evolving molecular concepts: the Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol 34(7):1392–1424. https://doi.org/10.1038/s41379-021-00779-w
Przybycin CG (2024) Papillary renal cell carcinoma: evolving classification by combined morphologic and molecular means. Adv Anat Pathol 31(3):147–156. https://doi.org/10.1097/PAP.0000000000000434
Article CAS PubMed Google Scholar
Wang Q, Zhang Y, Zhang B et al (2022) Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinoma. Nat Commun 13(1):31. https://doi.org/10.1038/s41467-021-27660-3
Article CAS PubMed PubMed Central Google Scholar
Al-Obaidy KI, Saleeb RM, Trpkov K et al (2022) Recurrent KRAS mutations are early events in the development of papillary renal neoplasm with reverse polarity. Mod Pathol 35(9):1279–1286. https://doi.org/10.1038/s41379-022-01018-6
Article CAS PubMed Google Scholar
Molinié V, Balaton A, Rotman S et al (2006) Alpha-methyl CoA racemase expression in renal cell carcinomas. Hum Pathol 37(6):698–703. https://doi.org/10.1016/j.humpath.2006.01.012
Article CAS PubMed Google Scholar
Jedlitschky G, Hoffmann U, Kroemer HK (2006) Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition. Expert Opin Drug Metabol Toxicol 2:351–366. https://doi.org/10.1517/17425255.2.3.351
Saleeb RM, Brimo F, Gao Y et al (2022) ABCC2 expression in papillary renal cell carcinoma provides better prognostic stratification than WHO/ISUP nucleolar grade. Hum Pathol 120:57–70. https://doi.org/10.1016/j.humpath.2021.12.006
Article CAS PubMed Google Scholar
Castillo VF, Masoomian M, Trpkov K et al (2023) ABCC2 brush-border expression predicts outcome in papillary renal cell carcinoma: a multi-institutional study of 254 cases. Histopathology 83(6):949–958. https://doi.org/10.1111/his.15042
Muriithi W, Macharia LW, Heming CP et al ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance. Cancer Biol Med 17(2):253–269. https://doi.org/10.20892/j.issn.2095-3941.2019.0284
Saleeb RM, Farag M, Lichner Z et al (2018) Modulating ATP binding cassette transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapy. Mol Oncol 12(10):1673–1688. https://doi.org/10.1002/1878-0261.12346
Comments (0)